Navigation Links
Cockroach allergens in homes associated with prevalence of childhood asthma in some neighborhoods
Date:5/17/2011

May 17, 2011 -- In New York City, the prevalence of asthma among children entering school varies by neighborhood anywhere from 3% to 19%, and children growing up within walking distance of each other can have 2-3 fold differences in risk for having asthma. In the first comprehensive effort to understand what drives these localized differences, researchers at Columbia University's Mailman School of Public Health compared the household presence of cockroach, mouse, cat, dust mite and other allergens in neighborhoods with a high prevalence of asthma to that in low-prevalence neighborhoods. They found that cockroach, mouse and cat allergens were significantly higher in homes located in neighborhoods where asthma is more common and that children in these higher-exposure homes were more likely to be sensitized to cockroach antigens.

The full study is now online in the Journal of Clinical Immunology.

The researchers studied 239 children 7 to 8 years old who were recruited through the middle-income HIP Health Plan of New York, as part of the ongoing New York City Neighborhood Asthma and Allergy Study. A total of 120 children lived in high asthma prevalence neighborhoods and 119 were from low-prevalence areas. Based on a parent reported survey of symptoms, 128 were classified as having asthma and 111 were assigned to a control group.

Allergen exposure was measured by collecting and analyzing bed dust samples from the upper half of the children's beds. Sensitization was measured by screening blood samples for antibodies to various household allergens. Earlier studies of inner-city children have found that exposure and sensitization to cockroach and mouse allergens is associated with having asthma.

Researchers found that cockroach, mouse and cat allergens were more prevalent in the bed dust taken from homes in high asthma neighborhoods than low asthma neighborhoods, and that sensitivity to cockroach allergen was twice as common: 23.7% versus 10.8%. However, there was no significant difference by neighborhood in sensitization mouse and cat antigens.

"Our findings demonstrate the relevance of exposure and sensitization to cockroach, mouse, dust mite, and cat in an urban community and suggest that cockroach allergen exposure could contribute to the higher asthma prevalence observed in some New York City neighborhoods," said Matthew Perzanowski, PhD, associate professor of Environmental Health Sciences and senior author.

"Although the relationships between allergen levels and household demographics have been examined in the U. S. on a national level, an advantage to focusing on a single city is the decreasing likelihood of confounding by regional differences, such as building types or climate," he noted.

Dr. Perzanowski also stresses that in this study of middle-income families in New York City it was a child's neighborhood income that was more important in predicting the likelihood of exposure to pests in the home than family income.

"In summary, significant differences in allergen exposure in homes throughout New York City have been demonstrated with this unique study cohort:

  • cockroach allergen was higher in the homes of the high asthma prevalence neighborhoods,
  • cockroach sensitization was higher among children living in neighborhoods with high rates of asthma,
  • cockroach allergen exposure was associated with sensitization, and
  • cockroach sensitization was associated with increased risk for asthma.

These findings combined point to cockroach allergen exposure potentially leading to a higher prevalence of asthma in some urban neighborhoods," said Dr. Perzanowski.


'/>"/>

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health
Source:Eurekalert

Related medicine news :

1. Avoid Allergens to Reap the Rewards of Gardening
2. 1 in 7 U.S. Nursing Homes Cited for Poor Infection Control
3. Penn State to help brush up oral hygiene in nursing homes
4. When Pets Outlive Owners, Retirement Homes Offer Refuge
5. Medical Homes Help Kids Get Comprehensive Care
6. Common insecticide used in homes associated with delayed mental development of young children
7. Daily Pill Dispensers an Asset in Homes for Elderly: Study
8. Good Child Care May Help Make Up for Troubled Homes
9. Warm Homes in Winter May Contribute to Obesity Epidemic
10. New Devices Help Seniors Stay Longer in Their Own Homes
11. Mentally Ill in Nursing Homes Often Lack Advance Care Plans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... ... 2017 , ... EpiGentek , a Farmingdale, NY-based biotech ... methylation “gold rush” with their established portfolio of optimized assay kits that measure ... m6A , RNA methylation has received a new burst in interest as ...
(Date:3/27/2017)... ... March 27, 2017 , ... The Anaheim Hills office accelerates ... National Capital has added 10 new sales professionals over the past 6 months and ... 15 additional new hires over the course of 2017. , “This new office ...
(Date:3/27/2017)... ... March 27, 2017 , ... From 1999 to ... responsible for over 33,000 of the 52,404 drug-related deaths in 2015.(2) To combat ... which proposes a tax on prescription opioids to fund drug rehabilitation and prevention ...
(Date:3/25/2017)... ... March 25, 2017 , ... Norland at Swissray is pleased to announce ... large subjects. The ELITE DXA has an active scan window, which is more than ... to fit in the scan area could not undergo an accurate total body bone density ...
(Date:3/24/2017)... , ... March 24, 2017 , ... Digital Scientists, a ... to announce the opening of a Greenville, South Carolina location. The lab ... progress in Greenville. , “We’ve been working with South Carolina clients for years from ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... SAN DIEGO and VANCOUVER, British Columbia, March 27, ... SPHS ) (the "Company" or "Sophiris"), a clinical ... treatment of patients with urological diseases, today reported ... and key corporate highlights. Key ... in Clinical Development for Localized Prostate Cancer. During ...
(Date:3/27/2017)... FinancialBuzz.com News Commentary  ... According to a new report by Arcview Market Research, the legal cannabis ... to $6.7 billion and can be expected to grow at a 27 ... from $6.7 billion in 2016, to $22.6 billion in 2021. This more ... cannabis without a doctor,s recommendation. Voters in California , ...
(Date:3/27/2017)... /PRNewswire/ - INVICTUS MD STRATEGIES CORP. ("Invictus MD" or ... is pleased to announce it has received conditional approval ... TSX Venture Exchange.  Receiving the conditional ... significant achievements for Invictus-MD. Some of which include: ... Laboratories Inc. ("AB Labs"), a Licensed Producer under the ...
Breaking Medicine Technology: