Navigation Links
Cocaine exposure during pregnancy leads to impulsivity in male, not female, monkeys
Date:10/22/2009

WINSTON-SALEM, N.C. Adult male monkeys exposed to cocaine while in the womb have poor impulse control and may be more vulnerable to drug abuse than female monkeys, even a decade or more after the exposure, according to a new study by researchers at Wake Forest University School of Medicine. The findings could lead to a better understanding of human drug abuse.

The study was presented yesterday at the annual Society for Neuroscience meeting in Chicago.

"This is the first time that so many different measures of impulsivity, which is considered a risk factor for drug abuse, have been looked at in the same group of animals," said Lindsey Hamilton, lead investigator and a graduate student working in the laboratory of Michael Nader, Ph.D., a professor of physiology and pharmacology. "We're looking for ways to predict which individuals are going to take drugs during their lives. It was very surprising to see that, even more than a decade after the prenatal cocaine exposure, the monkeys ended up being more impulsive and possibly more susceptible to drug use. It was particularly interesting, however, that this effect was only seen in the males. Something is either protecting the females from the effects of the cocaine exposure in the womb or making the males more susceptible to the lasting effects."

For the study, researchers compared adult monkeys both male and female prenatally exposed to cocaine more than 15 years ago, to monkeys who were raised under similar conditions, but not exposed to cocaine during gestation. To determine if the animals differed in impulse control, they performed four tests. For one of the tests, the researchers gave the animals the choice between pushing a lever that delivered a single banana pellet reward immediately or a lever that delivered several banana pellets, but required the animals to wait up to five minutes before the reward was delivered.

"That's where we saw very large differences betwe
'/>"/>

Contact: Jessica Guenzel
jguenzel@wfubmc.edu
336-716-3487
Wake Forest University Baptist Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. New treatment effective in counteracting cocaine-induced symptoms
2. Drug Detection Kits Manufactured By IDenta Corp. Shown During French Television Broadcast (at TF1) - Product Aids French Police In Bust of 600 Kilograms Of Cocaine
3. Cocaine Use Dulls Brains Sensitivity to Rewards
4. $2.2M NIH grant to develop drugs to suppress cocaine cravings
5. Catalyst Pharmaceutical Partners Announces Positive Phase II Trial Results for Vigabatrin in the Treatment of Cocaine Addiction
6. Cocaines effects on brain metabolism may contribute to abuse
7. Use of Methamphetamine Among U.S. Workers and Job Applicants Drops 22 Percent in 2007 and Cocaine Use Slows Dramatically, Reports Quest Diagnostics
8. Subordinate monkeys more likely to choose cocaine over food
9. Animal research suggests new strategy for treating cocaine addiction
10. Gene therapy reduces cocaine use in rats
11. Gene Therapy in Rats Reduces Cocaine Use
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... Seeking to make it tougher for people to misuse ... Thursday approved a new hydrocodone tablet that,s designed to ... the brand name Vicodin -- is a powerful opioid ... dangerous addictions across the United States. The FDA ... an extended-release tablet to treat pain severe enough to ...
(Date:11/21/2014)... November 21, 2014 MLF Biotech, Inc. ... cats . Liv-Pro® Probiotics for Pets helps maintain digestive ... to a pet's intestinal flora after it experiences a ... , Liv-Pro Probiotics for Pets is a proprietary blend ... contains seven live active bacteria strains that are safe ...
(Date:11/21/2014)... NJ (PRWEB) November 21, 2014 The ... homemade, high calorie dishes, plenty of gravy and a ... could be the best time of year to begin ... Diet Doc has uncovered the secret to losing unhealthy, ... the fattening holiday recipes. , The insight to Diet ...
(Date:11/21/2014)... Lauderdale, Florida (PRWEB) November 21, 2014 ... for chronic headaches and other jaw-related symptoms, ... patients seeking relief from chronic head pain, neck pain, ... , “This year we have seen a 52% ... treated. Our network of over 300 doctors and their ...
(Date:11/21/2014)... Even with years of experience under his belt, Kirk ... growth, participating in two recent events for his State Farm ... networking event with the leaders of State Farm and thousands ... and greatest in insurance news and products for his clients. ... (Stacy, Anthony, Reina and Jacob) as exhibitors at the recent ...
Breaking Medicine News(10 mins):Health News:FDA Approves 'Abuse-Resistant' Narcotic Painkiller 2Health News:FDA Approves 'Abuse-Resistant' Narcotic Painkiller 3Health News:MLF Biotech Introduces Liv-Pro Probiotics for Pets 2Health News:Diet Doc Releases New Calorie Loading Diet Plans - the Perfect Way to Jump Start the Metabolism and Begin Weight Loss During Thanksgiving 2Health News:Diet Doc Releases New Calorie Loading Diet Plans - the Perfect Way to Jump Start the Metabolism and Begin Weight Loss During Thanksgiving 3Health News:Diet Doc Releases New Calorie Loading Diet Plans - the Perfect Way to Jump Start the Metabolism and Begin Weight Loss During Thanksgiving 4Health News:National Rise In Patients Seeking Headache Relief 2Health News:Kirk Martin Insurance Agency Goes Local and National with State Farm 2
... stroke patients have not had a great track record ... Zealand focused on Maori and Pacific populations shows how ... and families in charge can make a difference to ... in the journal Clinical Rehabilitation , which is ...
... , TUESDAY, Nov. 15 (HealthDay News) -- Dieters appear to ... weight-loss counseling, two different studies suggest. Even if that ... can translate to more weight loss, the experts found. Either ... studies will be presented this week at the American Heart ...
... Nov. 15 (HealthDay News) --,Pneumonia is the most common infection ... also revealed that most infections occur about two weeks after ... are slated to present their findings Tuesday at the American ... not what we expected to find," study author Dr. Michael ...
... screening may increase awareness of the dangers of smoking and ... November 2011 issue of Otolaryngology-Head and Neck Surgery . ... 80% of head and neck cancers could be curbed by ... to date have had little impact reducing these mortalities. ...
... Disease Control and Prevention (CDC) has awarded Mayo Clinic ... in Ethiopia. The five-year award will support Mayo Clinic ... develop online education courses that disseminate best practices and ... The HIV eCurriculum project will be led by ...
... process. An early sign that it has begun is high ... insulin-producing beta cells are able to compensate for the increased ... sugar levels remain normal. It is not until the capacity ... 2 diabetes becomes a fact. The latter stage generally goes ...
Cached Medicine News:Health News:Putting stroke patients in charge improves quality of life 2Health News:Putting stroke patients in charge improves quality of life 3Health News:Looking to Lose Weight? Get a 'Coach' 2Health News:Looking to Lose Weight? Get a 'Coach' 3Health News:Pneumonia Most Common Infection After Heart Surgery 2Health News:Population-specific community-based cancer screening may discourage smoking 2Health News:CDC and Prevention awards Mayo Clinic an international medical education grant 2Health News:Molecular link between diabetes and cancer described 2
(Date:11/21/2014)...  Abaxis, Inc. (NasdaqGS: ABAX ), a ... the medical, research, and veterinary markets worldwide and providing ... in the United States , announced ... acquire 100% of QCR & Trio Diagnostics Limited, a ... The transaction closed on November 17, 2014. ...
(Date:11/21/2014)... MELVILLE, N.Y. , Nov. 21, 2014 ... one of the world,s largest health care services companies, ... the world,s largest provider of health care products and ... today announced that the companies have entered into a ... comprehensive service and product offerings to office-based medical practices.  ...
(Date:11/21/2014)... BRYDGES, Ontario , Nov. 20, 2014 /PRNewswire/ ... monitor mounting solutions and reading room environment guidance, ... their newest musculoskeletal radiology reading room, which may ... room designs at Penn Medicine. ... by the American College of Radiology,s Imaging 3.0 ...
Breaking Medicine Technology:Abaxis Acquires UK-based Distribution Organization 2Abaxis Acquires UK-based Distribution Organization 3Abaxis Acquires UK-based Distribution Organization 4Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 2Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 3Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 4Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 5RedRick Technologies Helps Penn Radiology Implement New Radiology Reading Room Concepts 2RedRick Technologies Helps Penn Radiology Implement New Radiology Reading Room Concepts 3
... 2011 PDI, Inc. (Nasdaq: PDII ) ... DIAGRAM™ software platform to enable eDetail delivery on popular ... ® and iPhone ® (1) and Android™(2)-based phones. ... devices even faster than the general population, we are ...
... April 25, 2011 Pharmatek Laboratories, Inc., a ... pharmaceutical industry, announced that it has added spray ...  The company has purchased a Buchi B-290 Mini ... clinical manufacture.  This technology can be used for ...
Cached Medicine Technology:PDI Announces Group DCA's Launch of eDetailing Across Apple® and Android™ Mobile Devices 2Pharmatek Laboratories Adds Spray Drying to Drug Development Services 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: