Navigation Links
Cluster of Genes Tied to Alcoholism

Finding part of ongoing research to determine how they affect risk in people

TUESDAY, March 2 (HealthDay News) -- There may be an association between alcoholism and a cluster of genes on chromosome 11, according to researchers who analyzed the genomes of nearly 1,900 white and black Americans.

Both genetic and environmental factors contribute to alcoholism. So far, researchers have identified several genes associated with the disorder.

"Previous studies have looked at one or a few genes at a time, choosing the genes based upon hypotheses about possible mechanisms underlying differences in risk for alcoholism," study corresponding author Howard J. Edenberg, from Indiana University School of Medicine, said in a news release. "We chose to examine the entire genome, all the genes at once, as an unbiased approach that has the potential of uncovering previously unsuspected genes."

The study findings will be published in the May print issue of the journal Alcoholism: Clinical & Experimental Research.

"Although we did not find definitive evidence for the role of any one gene, we found suggestive evidence that a gene or genes in one region of chromosome 11 might be involved," Edenberg said.

"We also provided support for several genes that had been found by others. Identifying additional genes that might be related to the risk for alcoholism is an important starting point. Future studies will need to confirm their importance in other populations, to determine which aspect of the disease process they might impact, and to examine the mechanisms through which they work."

Edenberg said this study is one stage in a large ongoing research effort.

"We will be working with other groups to replicate our findings and test their findings," he added. "We will be examining the aspects of alcoholism risk that are related to variations in each gene we identify, and starting functional studies of how the genetic variations affect cells and tissues. We have also embarked on a large and prospective study of adolescents and young adults, to examine the effects of genetic variations on the development of alcoholism and related disorders."

More information

The U.S. National Institute on Alcohol Abuse and Alcoholism has more about genes and alcoholism.

-- Robert Preidt

SOURCE: Alcoholism: Clinical & Experimental Research, news release, March 1, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Oxygen Therapy May Relieve Cluster Headache Pain
2. Adolescents gambling a part of a cluster of problem behaviors
3. Racial Clusters Seem to Affect Access to Colon Care
4. Common migraine pain condition also prevalent in cluster headache
5. Weaver Popcorn Company Issues a Nationwide Precautionary Voluntary Recall of 12 oz. (340g) Trails End(R) Chocolatey Peanut Clusters
6. A Cluster of Veterans Deaths; By Fred A. Baughman Jr., MD
7. Singapore Is One of the Fastest Growing Bioclusters in Asia; Wave of Investments in Drug Discovery and Translational Research
8. FDA Narrowing Tainted Tomato Probe to One Cluster
9. SGI Introduces the SGI BioCluster Life Sciences Workflow Solution
10. Consortium Health Plans Cuts Down on Power Usage and Cooling in Its Data Center Using ONStors Green Clustered NAS Solution
11. New Treatment Explored for Cluster Headaches
Post Your Comments:
(Date:11/25/2015)... ... 2015 , ... Finnleo, a leader in the traditional and far-infrared sauna industry, ... far-infrared saunas. , For traditional saunas, Finnleo is offering 20% off ... and Finnleo uses only European Grade A Nordic White Spruce from sustainably grown trees. ...
(Date:11/25/2015)... Nairobi (PRWEB) , ... November 26, 2015 , ... ... African Union Commission (AUC), European Union (EU), ANDI Pan African Centres of Excellence, ... Nations Office in Nairobi (UNON) for the opening of the 5th African Network ...
(Date:11/25/2015)... ... November 25, 2015 , ... Lakeview Health, a Jacksonville-based ... celebrate their sobriety and show through pictures what a positive difference it makes. ... Thanksgiving with the hashtag #FacesOfGratitude on their Facebook, Twitter, and Instagram accounts. ...
(Date:11/25/2015)... Lake, IL (PRWEB) , ... November 25, 2015 , ... ... to announce a recent successful appellate decision obtained by Attorneys Francisco J. Botto and ... case Adcock v. Illinois Workers’ Compensation Comm’n, 2015 IL App (2d) 130884WC. , According ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... Beddit® has ... Beddit Classic sleep tracking systems. The new app features a more intuitive SleepScore™ that ... understand how well you slept. The SleepScore is created by a proprietary algorithm. Beddit ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Research and Markets ( ) has announced ... Outlook to 2019 - Rise in Cardiac Disorders and Growing ... to their offering. Boston ... scientific and others. --> The market ... Boston scientific and others. ...
(Date:11/26/2015)... 2015 ... the  "2016 Future Horizons and Growth ... Testing Market: Supplier Shares, Competitive Intelligence, ... --> ) has ... Future Horizons and Growth Strategies in ...
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Drug Monitoring (TDM) Market: Supplier Shares, ... Opportunities"  report to their offering.  ... the addition of the  "2016 Future ...
Breaking Medicine Technology: