Navigation Links
Cluster of Genes Tied to Alcoholism
Date:3/2/2010

Finding part of ongoing research to determine how they affect risk in people

TUESDAY, March 2 (HealthDay News) -- There may be an association between alcoholism and a cluster of genes on chromosome 11, according to researchers who analyzed the genomes of nearly 1,900 white and black Americans.

Both genetic and environmental factors contribute to alcoholism. So far, researchers have identified several genes associated with the disorder.

"Previous studies have looked at one or a few genes at a time, choosing the genes based upon hypotheses about possible mechanisms underlying differences in risk for alcoholism," study corresponding author Howard J. Edenberg, from Indiana University School of Medicine, said in a news release. "We chose to examine the entire genome, all the genes at once, as an unbiased approach that has the potential of uncovering previously unsuspected genes."

The study findings will be published in the May print issue of the journal Alcoholism: Clinical & Experimental Research.

"Although we did not find definitive evidence for the role of any one gene, we found suggestive evidence that a gene or genes in one region of chromosome 11 might be involved," Edenberg said.

"We also provided support for several genes that had been found by others. Identifying additional genes that might be related to the risk for alcoholism is an important starting point. Future studies will need to confirm their importance in other populations, to determine which aspect of the disease process they might impact, and to examine the mechanisms through which they work."

Edenberg said this study is one stage in a large ongoing research effort.

"We will be working with other groups to replicate our findings and test their findings," he added. "We will be examining the aspects of alcoholism risk that are related to variations in each gene we identify, and starting functional studies of how the genetic variations affect cells and tissues. We have also embarked on a large and prospective study of adolescents and young adults, to examine the effects of genetic variations on the development of alcoholism and related disorders."

More information

The U.S. National Institute on Alcohol Abuse and Alcoholism has more about genes and alcoholism.



-- Robert Preidt



SOURCE: Alcoholism: Clinical & Experimental Research, news release, March 1, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Oxygen Therapy May Relieve Cluster Headache Pain
2. Adolescents gambling a part of a cluster of problem behaviors
3. Racial Clusters Seem to Affect Access to Colon Care
4. Common migraine pain condition also prevalent in cluster headache
5. Weaver Popcorn Company Issues a Nationwide Precautionary Voluntary Recall of 12 oz. (340g) Trails End(R) Chocolatey Peanut Clusters
6. A Cluster of Veterans Deaths; By Fred A. Baughman Jr., MD
7. Singapore Is One of the Fastest Growing Bioclusters in Asia; Wave of Investments in Drug Discovery and Translational Research
8. FDA Narrowing Tainted Tomato Probe to One Cluster
9. SGI Introduces the SGI BioCluster Life Sciences Workflow Solution
10. Consortium Health Plans Cuts Down on Power Usage and Cooling in Its Data Center Using ONStors Green Clustered NAS Solution
11. New Treatment Explored for Cluster Headaches
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... Rhinebeck, NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of ... of companies that call for a minimum wage raise to $12 an hour by 2020 ... wage. This will restore the lost value of the minimum wage, assure the wage floor ...
(Date:6/24/2016)... Georgia (PRWEB) , ... June 24, 2016 , ... ... awards today at the Clinical Decision Making in Emergency Medicine conference in Ponte ... have authored journal articles published in Emergency Medicine Practice and Pediatric ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions today ... cultivation and processing operations at its production facility, and opened its first two ... the manufacturer of a complete system of proactive air and surface purification solutions ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone ... executive with extensive sequencing and genomics experience, as Vice President of North American Capital ... will be responsible for leading the sales team in the commercialization of the HTG ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 The Biotechnology industry ... to present great opportunities to investors. Stock-Callers.com assesses the ... Corp. (NYSE: XON ), Vertex Pharmaceuticals Inc. ... ARNA ), and Regeneron Pharmaceuticals Inc. (NASDAQ: ... and receive your complimentary trade alerts at: ...
(Date:6/23/2016)... SAN DIEGO , June 23, 2016 /PRNewswire/ ... advancing programs that address medical conditions resulting from ... that it has appointed Greg Doyle ... member of Leading BioSciences, executive management team and ... officer and chief financial officer. He will provide ...
(Date:6/23/2016)... , June 23, 2016 Research ... Distribution in Europe 2016 Edition: The New Global Agenda " ... OTC Distribution in Europe ... that explores and tracks change. It identifies the driving factors ... for the consumer healthcare industry now and in the future. ...
Breaking Medicine Technology: