Navigation Links
Clues to Cell Death Could Fight Disease
Date:9/22/2007

Insights might produce treatments to kill off cancer cells, experts say

FRIDAY, Sept. 21 (HealthDay News) -- New information about a process called unplanned cell death, or necrosis, could help in the fight against heart disease, cancer, stroke and other life-threatening conditions, scientists say.

Necrosis is not the same as apoptosis -- natural, healthy programmed cell death. Necrosis is an unplanned cell death caused by outside factors, such as traumatic injury or infection.

It was long believed that the process of necrosis was chaotic and irreversible, note researchers at the University of Pittsburgh School of Medicine. But their new study suggests the process may actually be triggered as part of a regulated response to stress by a powerful protein called SRP-6. This protein can also potentially halt cell necrosis, the researchers explained.

It may be possible to harness SRP-6 to direct certain cells -- such as those in cancerous tumors -- to die off, or to save other kinds of cells, such as the degenerating neural cells that cause Alzheimer's and Parkinson's diseases.

The study appears in the Sept. 21 issue of Cell.

"For years, we believed that cell death related to a catastrophic insult such as stroke or heart attack that deprives tissue of oxygen couldn't really be treated, so we focused on strategies to prevent further damage by restoring blood flow as quickly as possible with clot busters and surgery," study senior author Dr. Gary A. Silverman, chief of newborn medicine in the department of pediatrics, said in a prepared statement.

"But our research indicates that necrosis can be interrupted and possibly repaired, even after the injury process is well underway. This insight has exciting implications for the management of heart disease, stroke and neurological illness," he said.

More information

For more on the life of the cell, head to the City University of New York.



-- Robert Preidt



SOURCE: University of Pittsburgh Schools of the Health Sciences, news release, Sept. 20, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New clues about immune system from leprosy microbes
2. New clues to maternal aggressive behavior
3. Monkeys offer genetic clues to adult blindness
4. Innovative yeast genome may handle Cancer Clues
5. Researchers Discover New Clues To Identify Tooth Decay
6. Leeches Provide Clues Regarding The Prevention Of Heart Disease
7. Excavations Reveal Clues Of Early Warfare
8. Sleeping Computers Yield Clues About Genetic Disorders
9. Transporter offers reliable clues for safer pain medicine
10. Clues To Identify Psychological Seizures
11. A Human Brain Gene Could Hold Clues On The Evolution Of Brain Capacity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... ... technology to revolutionize the emergency ambulance transport experience for the millions of people ... how Uber has disrupted the taxi industry through the use of technology. Now, ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Pixel Film ... Pro X. , "Film editors can give their videos a whole new perspective by ... Austin - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 ...
(Date:6/25/2016)... ... 25, 2016 , ... Experts from the American Institutes for ... Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR ... care planning, healthcare costs and patient and family engagement. , AIR researchers will ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, ... the latter, setting the bar too high can result in disappointment, perhaps even self-loathing. ... toward their goal. , Research from PsychTests.com reveals that behind the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Collagen Matrix, Inc., ("Collagen Matrix") ... manufacturing of collagen and mineral based medical devices ... Bill Messer has joined the company ... leverage the growing portfolio of oral surgery, neurosurgery, ... Bill joins the Collagen Matrix executive team as ...
(Date:6/24/2016)... Research and Markets has ... 2015-2025: Applications, Technologies, Forecasts" report to their ... Electronics, Smart Skin, Structural Health Monitoring, Composite Smart ... electronics involves electronic and/or electrical components and circuits ... structures such as vehicle bodies or conformally placed ...
(Date:6/24/2016)... Research and Markets has announced the ... Tests" report to their offering. ... The World Market for Companion Diagnostics covers the ... analysis in the report includes the following: ... Kits) by Region (N. America, EU, ROW), 2015-2020 , ...
Breaking Medicine Technology: