Navigation Links
Clues to Cell Death Could Fight Disease
Date:9/22/2007

Insights might produce treatments to kill off cancer cells, experts say

FRIDAY, Sept. 21 (HealthDay News) -- New information about a process called unplanned cell death, or necrosis, could help in the fight against heart disease, cancer, stroke and other life-threatening conditions, scientists say.

Necrosis is not the same as apoptosis -- natural, healthy programmed cell death. Necrosis is an unplanned cell death caused by outside factors, such as traumatic injury or infection.

It was long believed that the process of necrosis was chaotic and irreversible, note researchers at the University of Pittsburgh School of Medicine. But their new study suggests the process may actually be triggered as part of a regulated response to stress by a powerful protein called SRP-6. This protein can also potentially halt cell necrosis, the researchers explained.

It may be possible to harness SRP-6 to direct certain cells -- such as those in cancerous tumors -- to die off, or to save other kinds of cells, such as the degenerating neural cells that cause Alzheimer's and Parkinson's diseases.

The study appears in the Sept. 21 issue of Cell.

"For years, we believed that cell death related to a catastrophic insult such as stroke or heart attack that deprives tissue of oxygen couldn't really be treated, so we focused on strategies to prevent further damage by restoring blood flow as quickly as possible with clot busters and surgery," study senior author Dr. Gary A. Silverman, chief of newborn medicine in the department of pediatrics, said in a prepared statement.

"But our research indicates that necrosis can be interrupted and possibly repaired, even after the injury process is well underway. This insight has exciting implications for the management of heart disease, stroke and neurological illness," he said.

More information

For more on the life of the cell, head to the City University of New York.



-- Robert Preidt



SOURCE: University of Pittsburgh Schools of the Health Sciences, news release, Sept. 20, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New clues about immune system from leprosy microbes
2. New clues to maternal aggressive behavior
3. Monkeys offer genetic clues to adult blindness
4. Innovative yeast genome may handle Cancer Clues
5. Researchers Discover New Clues To Identify Tooth Decay
6. Leeches Provide Clues Regarding The Prevention Of Heart Disease
7. Excavations Reveal Clues Of Early Warfare
8. Sleeping Computers Yield Clues About Genetic Disorders
9. Transporter offers reliable clues for safer pain medicine
10. Clues To Identify Psychological Seizures
11. A Human Brain Gene Could Hold Clues On The Evolution Of Brain Capacity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can now ... and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings ... The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle ... chronic pain and the benefits of holistic treatments, Serenity Recovery Center of ... Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, ... and the Road To Recovery® program to drive cancer patients to and from their ... to ensure the highest quality of life and ongoing independence. Getting to and ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations at ... Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical Systems ... "Company"), which develops, markets and sells medical devices and ... , signed a strategic cooperation agreement with Hongyuan Supply ... Supply Chain") on June 20, 2016, to develop Dehaier,s ... strategic cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s ...
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... report to their offering. ... failure, it replaces the function of kidneys by removing the ... the treatment helps to keep the patient body,s electrolytes such ... Increasing number of ESRD patients & substantial healthcare expenditure on ...
Breaking Medicine Technology: