Navigation Links
Clues to Cell Death Could Fight Disease
Date:9/22/2007

Insights might produce treatments to kill off cancer cells, experts say

FRIDAY, Sept. 21 (HealthDay News) -- New information about a process called unplanned cell death, or necrosis, could help in the fight against heart disease, cancer, stroke and other life-threatening conditions, scientists say.

Necrosis is not the same as apoptosis -- natural, healthy programmed cell death. Necrosis is an unplanned cell death caused by outside factors, such as traumatic injury or infection.

It was long believed that the process of necrosis was chaotic and irreversible, note researchers at the University of Pittsburgh School of Medicine. But their new study suggests the process may actually be triggered as part of a regulated response to stress by a powerful protein called SRP-6. This protein can also potentially halt cell necrosis, the researchers explained.

It may be possible to harness SRP-6 to direct certain cells -- such as those in cancerous tumors -- to die off, or to save other kinds of cells, such as the degenerating neural cells that cause Alzheimer's and Parkinson's diseases.

The study appears in the Sept. 21 issue of Cell.

"For years, we believed that cell death related to a catastrophic insult such as stroke or heart attack that deprives tissue of oxygen couldn't really be treated, so we focused on strategies to prevent further damage by restoring blood flow as quickly as possible with clot busters and surgery," study senior author Dr. Gary A. Silverman, chief of newborn medicine in the department of pediatrics, said in a prepared statement.

"But our research indicates that necrosis can be interrupted and possibly repaired, even after the injury process is well underway. This insight has exciting implications for the management of heart disease, stroke and neurological illness," he said.

More information

For more on the life of the cell, head to the

Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. New clues about immune system from leprosy microbes
2. New clues to maternal aggressive behavior
3. Monkeys offer genetic clues to adult blindness
4. Innovative yeast genome may handle Cancer Clues
5. Researchers Discover New Clues To Identify Tooth Decay
6. Leeches Provide Clues Regarding The Prevention Of Heart Disease
7. Excavations Reveal Clues Of Early Warfare
8. Sleeping Computers Yield Clues About Genetic Disorders
9. Transporter offers reliable clues for safer pain medicine
10. Clues To Identify Psychological Seizures
11. A Human Brain Gene Could Hold Clues On The Evolution Of Brain Capacity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... NY (PRWEB) May 28, 2015 The ... Care are proud to present Dr. Alicia Almendral as ... be a big part of the newly opened facility’s ... finest in modern cosmetic treatments. , Dr. Almendral is ... in the latest anti-aging and cosmetic enhancement techniques. Her ...
(Date:5/28/2015)... VA (PRWEB) May 28, 2015 ... the 351(k) Application Process, **FDAnews Webinar**, June 23, ... [http://www.fdanews.com/BiosimilarsApproval , On June 23, 2015, ... of two leading intellectual property attorneys from the ... Success Strategies for Biosimilars Approval: A Roadmap to ...
(Date:5/28/2015)... NJ (PRWEB) May 28, 2015 The Boys ... of $2,500 from Horizon Blue Cross Blue Shield of New ... golfer Natalie Gulbis, the club can receive much more support ... by Acer. , A former Boys & Girls Club member ... in Sacramento, California, Ms. Gulbis has accepted the Horizon Blue ...
(Date:5/28/2015)... AMVETS leaders this week congratulated AMVETS ... Davis of Newark, Del. AMVETS National Commander Larry Via ... the $10,000 sweepstakes grand prize. , AMVETS selected the ... around the country for prizes ranging from $500 to ... May 21 at the AMVETS National Headquarters in Lanham, ...
(Date:5/28/2015)... May 28, 2015 As the summer approaches, ... keep cool. It’s important to make safety a top priority, ... some swimming tips. , According to the Centers for Disease ... United States, not including boating incidents. Additionally, the National Safety ... children ages 1 to 4. , Amica is sharing ...
Breaking Medicine News(10 mins):Health News:Bella Diosa Med Spa Welcomes Botox Specialist to Yonkers Community 2Health News:FDAnews Announces — Success Strategies for Biosimilars Approval: A Roadmap to the 351(k) Application Process Webinar, June 23, 2015 2Health News:FDAnews Announces — Success Strategies for Biosimilars Approval: A Roadmap to the 351(k) Application Process Webinar, June 23, 2015 3Health News:Golf Pro Natalie Gulbis to Chip in with Horizon Blue Cross Blue Shield of New Jersey to Support Boys & Girls Club of Atlantic City 2Health News:Golf Pro Natalie Gulbis to Chip in with Horizon Blue Cross Blue Shield of New Jersey to Support Boys & Girls Club of Atlantic City 3Health News:AMVETS Announces Summer Sweepstakes Winners 2Health News:Splash! Amica Shares 6 Swimming Safety Tips 2
... muscle cells in blood vessels hasten the development of ... published online today in the journal Nature . ... of Cardiovascular Disease (GICD) in San Francisco, with key ... University of Rochester School of Medicine and Dentistry. ...
... Congress members ... citizens aware of the dilemmas and decisions to be made in regards to family health ... ... break, members of Congress will resume talks about health care reform for United States citizens. ...
... Taking simple precautions can help prevent pain and injury, ... baby boomers are not as young as they used to ... precautions are in order to stay injury-free. , ... protect themselves from injuries when exercising," Dr. Ray Monto, a ...
... in microbiology testing walks on four legs and says ... of the familiar woolly barnyard resident. A new study ... to be published July 3 in PLoS ONE ... and parasite-resistant, they,re also perfect blood donors for the ...
... DEBRECEN, Hungary, July 3 Bertalan Mesko, medical blogger ... e-guide for medical professionals focusing on how ... conferences are expensive and patients are also open to ... enter a virtual realm and organize medical presentations and ...
... will lead to treatments, , FRIDAY, July 3 (HealthDay News) ... flaw that may drive the rapid spread of relapsed lung ... treated. But most cases are not detected until the disease ... into remission, the disease often springs back more virulent than ...
Cached Medicine News:Health News:Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels 2Health News:Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels 3Health News:Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels 4Health News:Congress Resumes Health Care Talks After Independence Day Break 2Health News:Exercise Tips to Keep Boomers on Their Feet 2Health News:Rare sheep could be key to better diagnostic tests in developing world, says Stanford study 2Health News:Rare sheep could be key to better diagnostic tests in developing world, says Stanford study 3Health News:Cell Pathway May Be Key to Lung Cancer's Spread 2Health News:Cell Pathway May Be Key to Lung Cancer's Spread 3
(Date:5/28/2015)... SAN FRANCISCO, Calif. , May 28, 2015 /PRNewswire/ ... treatment of cancer, today announced that Sean McCarthy ... the upcoming Jefferies 2015 Global Healthcare Conference ... p.m. EDT on Tuesday, June 2, 2015. Dr. McCarthy ... the company,s Precision cancer immunotherapy and Probody drug conjugate ...
(Date:5/28/2015)... 28, 2015  Shareholder rights law firm Robbins ... officers and directors of Eleven Biotherapeutics, Inc. (NASDAQGM: EBIO) ... is a clinical-stage biopharmaceutical company that engages in ... treat eye diseases, primarily in the ... this press release on the law firm,s Shareholder ...
(Date:5/28/2015)... Eli Lilly and Company (NYSE: LLY ) and Incyte ... June 11 to discuss data from the first two pivotal ... two trials, RA-BEACON and RA-BUILD, will be presented on June ... in Rome, Italy . The ... Time. The live audio webcast can be accessed through a ...
Breaking Medicine Technology:Robbins Arroyo LLP Is Investigating the Officers and Directors of Eleven Biotherapeutics, Inc. (EBIO) on Behalf of Shareholders 2Lilly and Incyte Announce Webcast to Discuss Baricitinib Phase III Data 2Lilly and Incyte Announce Webcast to Discuss Baricitinib Phase III Data 3
... ... Clinical Duration, CAMBRIDGE, Mass., March 10 ... large, multicenter,observational study that investigated the long-term durability of,Carticel(R) (autologous cultured ... the articular cartilage of their,knee. These findings revealed that almost 90 ...
... The,Journal of the American College of Cardiology has ... Performance of PTCA in,Patients Without Documented Ischemia) as one ... in 2007, according to an article entitled,"Highlights of the ... al. (JACC,Vol. 51, No. 4, 2008 January 29, 2008:490-512), ...
Cached Medicine Technology:Genzyme Announces Presentation of New Positive Data on Carticel(R) 2Genzyme Announces Presentation of New Positive Data on Carticel(R) 3Genzyme Announces Presentation of New Positive Data on Carticel(R) 4Genzyme Announces Presentation of New Positive Data on Carticel(R) 5Genzyme Announces Presentation of New Positive Data on Carticel(R) 6JACC Identifies DEFER with 5-year Outcomes as Landmark Trial 2
... The Techne TC-512 has a graphical touch ... your experiments at the "touch of a ... Wide linear gradient, Touch Screen, Graphical Display, ... Performance, Versatile Block Format, Intuitive Programmin, Free ...
... Techne TC412 is a high performance, high sample ... Features & Benefits include: Flexible block format, ... 8 peltiers, PC networking. Includes a four ... 32 Techne cyclers can be connected and run ...
... a compact design for personal use, yet is able ... up to 32 samples simultaneously. It contains a heating ... to add mineral oil to prevent evaporation of the ... and up to 15 steps can be freely connected ...
... cycler is the smallest footprint two-bay thermal ... ever before. The Disciple instrument ... communications to a computer using a remote ... thermal cycler contains the latest in power ...
Medicine Products: