Navigation Links
Clues to Cell Death Could Fight Disease
Date:9/22/2007

Insights might produce treatments to kill off cancer cells, experts say

FRIDAY, Sept. 21 (HealthDay News) -- New information about a process called unplanned cell death, or necrosis, could help in the fight against heart disease, cancer, stroke and other life-threatening conditions, scientists say.

Necrosis is not the same as apoptosis -- natural, healthy programmed cell death. Necrosis is an unplanned cell death caused by outside factors, such as traumatic injury or infection.

It was long believed that the process of necrosis was chaotic and irreversible, note researchers at the University of Pittsburgh School of Medicine. But their new study suggests the process may actually be triggered as part of a regulated response to stress by a powerful protein called SRP-6. This protein can also potentially halt cell necrosis, the researchers explained.

It may be possible to harness SRP-6 to direct certain cells -- such as those in cancerous tumors -- to die off, or to save other kinds of cells, such as the degenerating neural cells that cause Alzheimer's and Parkinson's diseases.

The study appears in the Sept. 21 issue of Cell.

"For years, we believed that cell death related to a catastrophic insult such as stroke or heart attack that deprives tissue of oxygen couldn't really be treated, so we focused on strategies to prevent further damage by restoring blood flow as quickly as possible with clot busters and surgery," study senior author Dr. Gary A. Silverman, chief of newborn medicine in the department of pediatrics, said in a prepared statement.

"But our research indicates that necrosis can be interrupted and possibly repaired, even after the injury process is well underway. This insight has exciting implications for the management of heart disease, stroke and neurological illness," he said.

More information

For more on the life of the cell, head to the City University of New York.



-- Robert Preidt



SOURCE: University of Pittsburgh Schools of the Health Sciences, news release, Sept. 20, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New clues about immune system from leprosy microbes
2. New clues to maternal aggressive behavior
3. Monkeys offer genetic clues to adult blindness
4. Innovative yeast genome may handle Cancer Clues
5. Researchers Discover New Clues To Identify Tooth Decay
6. Leeches Provide Clues Regarding The Prevention Of Heart Disease
7. Excavations Reveal Clues Of Early Warfare
8. Sleeping Computers Yield Clues About Genetic Disorders
9. Transporter offers reliable clues for safer pain medicine
10. Clues To Identify Psychological Seizures
11. A Human Brain Gene Could Hold Clues On The Evolution Of Brain Capacity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... ... 24, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... generation. Yisrayl makes an astounding statement when he says that the entire Bible ... Bible details the current times so plainly that anyone should be able to see ...
(Date:2/24/2017)... ... February 24, 2017 , ... Rosica Communications, a national ... , media relations, social media, content marketing and SEO, is now offering direct, ... an intuitive marketing automation platform. , Rosica will now offer the platform to ...
(Date:2/23/2017)... ... February 23, 2017 , ... On February 22, 2017 ... letter to withdraw previous guidance issued by the Obama Administration requiring schools ... in May 2016 by the Obama Administration came in response to a growing ...
(Date:2/23/2017)... ... February 23, 2017 , ... The American Cleft Palate-Craniofacial Association (ACPA) is ... KLS is a longtime supporter of the event. , "We are pleased that ... said Dr. Bob Havlik, 2017 ACPA President. "KLS Martin has a long track record ...
(Date:2/23/2017)... ... February 23, 2017 , ... EBSCO Information Services ... Institute for Health and Care Excellence (NICE) framework. The agreement allows purchasers ... (NHS) to search, order and purchase medical and healthcare-related content through GOBI ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... -- Research and Markets has announced the addition of ... Forecast to 2025" report to their offering. ... The Global Wireless Health Market ... the next decade to reach approximately $330.5 billion by 2025. ... all the given segments on global as well as regional levels ...
(Date:2/24/2017)... Physician General Dr. Rachel Levine ... Jennifer Smith commended South Central EMS today for ... naloxone, a life-saving overdose reversal drug. The recognition event ... and overdose survivor who was saved due to the ... significant part of fighting the opioid epidemic is making ...
(Date:2/24/2017)... 23, 2017 Report analyzes the worldwide markets for ... analytics for the US, Canada , ... Asia-Pacific , Latin America , ... for the period 2015 through 2022. Also, a six-year historic ... are derived from primary and secondary research. Company profiles are ...
Breaking Medicine Technology: