Navigation Links
Clues to Alzheimer's Spotted Earlier in Disease

Researchers found biomarkers in patients with only mild memory problems

WEDNESDAY, June 24 (HealthDay News) -- Biomarkers for Alzheimer's disease can be detected in the cerebrospinal fluid in the very early stages of the disease, a Swedish study suggests.

University of Gothenburg researchers analyzed cerebrospinal fluid (CSF) samples from 168 patients and found the typical pattern of biomarkers known as the "CSF AD profile" present in patients with mild memory problems, which is earlier than the illness could be detected by current tests.

"The earlier we can catch Alzheimer's disease, the more we can do for the patient," researcher Kaj Blennow said in a university news release. "The patients who had the typical changes in biomarker profile of the cerebrospinal fluid had a risk of deterioration that was 27 times higher than the control group. We could also see that all patients with mild cognitive impairment who deteriorated and developed Alzheimer's disease had these changes in the biomarker profile of their cerebrospinal fluid."

The study also found a relationship between the CFS AD profile and other typical signs of Alzheimer's, including the presence of the gene APOE e4 and deterioration of the area of the brain that controls memory.

Their discovery will have major significance "if the new type of pharmaceutical that can directly slow the progression of the disease proves to have a clinical effect," Blennow said. "It is important in this case to start treatment before the changes in the brain have become too severe," he added.

The study, which included patients from seven European countries, appears in the current issue of Lancet Neurology.

More information

The U.S. National Institute on Aging has more about the stages and symptoms of Alzheimer's disease.

-- Robert Preidt

SOURCE: University of Gothenburg, Sweden, news release, June 22, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Clues to Muscular Dystrophy Seen in Womb
2. Study gives clues to how adrenal cancer forms
3. Gene Gives Clues to Why Autism More Common in Boys
4. Singing brains offers epilepsy and schizophrenia clues
5. Genes Yield Clues to High Blood Pressure
6. Young Womens Breast Tissue Offers Clues to Cancer Risk
7. Potential lung disease biomarkers yield clues to COX-2 inhibitor side effects
8. Zebrafish offer clues to treatments for motor neurone disease
9. Cat Food-Linked Illness Yields Clues to MS
10. Brain Cells Give New Clues to Alzheimers
11. Clues Found to Brain Mechanism Behind Migraines
Post Your Comments:
Related Image:
Clues to Alzheimer's Spotted Earlier in Disease
(Date:6/26/2016)... ... ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect Plugin ... whole new perspective by using the title layers in ProSlice Levels to split-up ... Levels contains over 30 Different presets to choose from. FCPX users can ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the largest ... as the Medical Director of its new Mesquite-Samuell Farm facility. , “We are ... Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from reveals ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... LEXINGTON, Mass. , June 24, 2016   ... specialty pharmaceutical company developing innovative inhaled drugs, announced today ... when Russell Investments reconstituted its comprehensive set ... 2016. "This is an important milestone for ... "It will increase shareholder awareness of our progress in ...
(Date:6/23/2016)... HOUSTON , June 23, 2016  MedSource ... platform as its e-clinical software solution of choice.  ... the best possible value to their clients by ... nowEDC.  The preferred relationship establishes nowEDC as the ... pricing for MedSource,s full-service clients.  "nowEDC has long ...
(Date:6/23/2016)... Research and Markets has announced the addition ... Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, Binder, ... Forecast to 2021" report to their offering. ... excipients market is projected to reach USD 8.1 Billion ... forecast period 2016 to 2021. The ...
Breaking Medicine Technology: