Navigation Links
Clot-Busting Therapy Under Review
Date:9/28/2009

Cardiologists looking at new generation of drugs as Plavix trial shows double dosage best for angioplasty

MONDAY, Sept. 28 (HealthDay News) -- Even as they digest the latest news on what dose of the clot-dissolving drug Plavix is best during angioplasty, cardiologists are looking at the next generation of clot-busters that could replace Plavix.

Clot-dissolving therapy was the big buzz among cardiologists at last week's Transcatheter Cardiovascular Therapeutics conference in San Francisco, according to Dr. Daniel I. Simon, a professor of cardiovascular research at Case Western Reserve University School of Medicine in Cleveland.

"What is the best dose of Plavix to be used in heart attacks?" Simon asked. "That is the number one question in cardiology."

But right behind that question is one about the role of two new antiplatelet agents -- prasugrel (Effient), which was approved by the U.S. Food and Drug Administration in July, and ticagrelor (Brilinta), which is expected to be submitted for FDA approval by the end of this year.

Trials have shown that both drugs can be more effective at keeping arteries open while reducing the risk of excess bleeding, which is the main hazard of Plavix (clopidogrel), Simon said.

"You have to balance the risk of bleeding, which is a safety issue, with efficacy, preventing heart attack and stroke," he said. "The more potent an antiplatelet agent you have, the more bleeding you might have. There are investigations that have been published showing that increasing the dose of clopidogrel can improve efficacy without more bleeding. We are trying to get to a sweet spot."

Platelets are the cells that clump together to form artery-blocking clots.

The latest of those trials, published in the Oct. 6 issue of the Journal of the American College of Cardiology, found that a 600-milligram dose of Plavix is more effective than a 300-milligram dose during angioplasty
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Clot-Busting Drug Offers New Approach to DVT
2. Researchers fine-tune clot-busting treatment for bleeding in brain
3. Clot-Busting Treatment Improves Bleeding Stroke Outcomes
4. Few Stroke Patients Get Clot-Busting Drug
5. Vision restoration therapy shown to improve brain activity in brain injured patients
6. HIV therapy in pregnancy-data support WHO recommendations
7. Family-based treatment more effective than supportive psychotherapy in treating bulimia
8. Trial to Test Gene Therapy for Angina in Women
9. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
10. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
11. Chemotherapy may be culprit for fatigue in breast cancer survivors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Clot-Busting Therapy Under Review
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... been successfully treated for their disease face the ... testicular) tissue is transplanted back into their bodies ... university hospitals in Israel. , Writing in Europes ... 22 April), the researchers say that hundreds of ...
... ,biological mechanism, that leads to adverse reactions identified, officials ... heparin products have now been found in at least ... ongoing surveillance measures to ensure the safety of the ... addition, officials said contaminated lots of the blood thinner ...
... stories of suffering from trauma victims causes serious psychological ... suggests. , In a study appearing in the May ... Investigator Joseph Boscarino, PhD, MPH and his co-researchers examined ... New York City social workers following the Sept. 11 ...
... highlights:, -- Record quarterly net sales of $668.2 million, up 13.4% year over year and ... share, up 12.5% over the same period last year, -- Record quarterly Catalysts segment income of $51.7 million resulting ... ... First Quarter ...
... OMCL ), a leading provider of system solutions ... quarter ended,March 31, 2008., GAAP results: Revenues for ... million or 7.2% from the fourth quarter of 2007 ... of 2007., First quarter 2008 net income as ...
... ISTA,Pharmaceuticals, Inc. (Nasdaq: ISTA ), today announced ... 30, 2008, after the U.S. markets,close. ISTA will host ... results at 4:30 p.m. Eastern Time on April 30., ... Canadian participants may,dial 866-362-5158; international participants may dial 617-597-5397. ...
Cached Medicine News:Health News:Cancer could return unless stored ovarian tissue undergoes adequate testing before re-implantation 2Health News:Cancer could return unless stored ovarian tissue undergoes adequate testing before re-implantation 3Health News:FDA: Contaminated Heparin Found in 10 Countries 2Health News:FDA: Contaminated Heparin Found in 10 Countries 3Health News:FDA: Contaminated Heparin Found in 10 Countries 4Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 2Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 3Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 4Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 5Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 6Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 7Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 8Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 9Health News:Albemarle Reports Record Quarterly Net Sales and Operating Results 10Health News:Omnicell Announces First Quarter 2008 Results 2Health News:Omnicell Announces First Quarter 2008 Results 3Health News:Omnicell Announces First Quarter 2008 Results 4Health News:Omnicell Announces First Quarter 2008 Results 5Health News:Omnicell Announces First Quarter 2008 Results 6Health News:Omnicell Announces First Quarter 2008 Results 7Health News:Omnicell Announces First Quarter 2008 Results 8Health News:Omnicell Announces First Quarter 2008 Results 9Health News:Omnicell Announces First Quarter 2008 Results 10Health News:Omnicell Announces First Quarter 2008 Results 11
(Date:12/15/2014)... 15, 2014  Stephen Squires, CEO and founder of ... Corp (OTCQB:QTMM), will be speaking at the launch ... on December 16th, 2014. The RCQM launch continues Rice ... attracting top faculty and students and by inviting the ... "We have a long association with ...
(Date:12/15/2014)... Government of Ghana has endorsed a project ... Terumo BCT to respond to the emerging Ebola crisis within ... system capacity to the citizens of Ghana . ... and Resilience Initiative (GERRI) is a multi-agency effort designed to: ... arrival of the Ebola epidemic , Provide new blood product ...
(Date:12/14/2014)... 2014  ChartSpan, a consumer platform for patients managing ... iPad medical app in the United States ... ChartSpan is an iPhone and iPad ... and send electronic healthcare records. The product was built ... of waiting for the healthcare system to deliver on ...
Breaking Medicine Technology:Quantum Materials CEO Stephen Squires to Speak at Rice Center for Quantum Materials Launch 2Quantum Materials CEO Stephen Squires to Speak at Rice Center for Quantum Materials Launch 3Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 2Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 3Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 4Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 5Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 6ChartSpan Becomes The Most Downloaded Medical App in America 2ChartSpan Becomes The Most Downloaded Medical App in America 3
... , , , , ... and development company, announced today that it has closed a $6.5M Series ... technology for CM-AT for autism. Phase III clinical trials are about to ... "The Series A funding will allow us to complete our clinical trials ...
... , LOS ANGELES, Aug. 7 A new ... any drug and sealed to the outer surface (episclera) of the ... of medicines for retinal and vitreous diseases, according to a new ... in The Vision Center at Children,s Hospital Los Angeles. Dr. Murphree ...
Cached Medicine Technology:Curemark Closes Series A Financing 2Tiny Cup Attached to Eye Improves Drug Delivery For Retinal Diseases 2Tiny Cup Attached to Eye Improves Drug Delivery For Retinal Diseases 3Tiny Cup Attached to Eye Improves Drug Delivery For Retinal Diseases 4
... and model 1488 active-fixation leads are among ... the unsurpassed handling advantages, performance, and reliability ... active-fixation leads. Implantable with a 7 F ... Tendril SDX lead is designed to lower ...
... Tendril SDX model 1688 and model 1488 ... extendable/retractable pacing leads, offering the unsurpassed handling ... Jude Medical's line of active-fixation leads. Implantable ... body diameter of the Tendril SDX lead ...
... battery-backed up, microprocessor based, quality instrument that monitors ... and displays a chart on its large panel ... or zoomed into and out of, so that ... months can be seen at one time. ...
... Aegis CheckPoint is an automated, wireless, ... and alert system for refrigerator, freezer, ... chart recorders, data loggers and manual ... on an existing PC and comes ...
Medicine Products: