Navigation Links
Closing hole in the heart no better than drugs in preventing strokes
Date:3/16/2012

MAYWOOD, Il. -- Loyola University Medical Center is one of the major enrollers in a landmark clinical trial that found that plugging a hole in the heart works no better than drugs in preventing strokes.

The study is published in the New England Journal of Medicine. Loyola enrolled 24 patients, one of the highest patient enrolments in the multicenter trial, and more than any other Chicago-area hospital. Principal investigators at the Loyola site are stroke specialist Dr. Michael Schneck and interventional cardiologist Dr. Fred Leya.

About 1 in 4 adults has a small hole in the wall that separates the top two chambers of the heart. It's called a patent foramen ovale (PFO). For most people, a PFO poses no problems. But in some cases, a clot can pass through the hole, migrate to the brain and trigger a stroke.

The standard treatment is medication to prevent blood clots, typically aspirin or Coumadin. A newer treatment is to plug the hole with a device delivered by a catheter. The catheter is inserted into a blood vessel at the top of the leg and guided up to the heart. When the catheter reaches the PFO, the device is deployed, opening like an umbrella to plug the hole.

The clinical trial included 909 patients who had PFOs, and had previously suffered strokes or mini strokes called transient ischemic attacks (TIAs). They were randomly assigned to receive a PFO closure device plus blood thinners or drug therapy alone.

The closure device worked no better than drugs alone in preventing recurrent strokes or TIAs. Moreover, major vascular complications occurred in 3.2 percent of the closure group.

"Medical therapy is just as good as the device," Schneck said. "The larger lesson is that we have an impetus in the United States for doing procedures without first standing back and asking all the right questions."

Leya noted the clinical trial used an older version of a closure device. "I would like to see more research to determine if better devices will have better results," he said.
'/>"/>

Contact: Jim Ritter
jritter@lumc.edu
708-216-2445
Loyola University Health System
Source:Eurekalert

Related medicine news :

1. Labopharm announces closing of US$20 million public offering of units
2. Closing the science-to-policy gap in maternal and child health in Africa
3. 1 in 5 Parents Missed Work for H1N1 School Closings: Survey
4. U.S. Nursing Home Closings Hit Poor Neighborhoods Hardest: Study
5. Closing Schools Seems to Prevent Flus Spread
6. Fear of Antidepressants Keep Many From Disclosing Depression
7. Closing in on an ulcer- and cancer-causing bacterium
8. ICU Patients at Risk for Rare Heart Rhythm Problem
9. Cook With Love This Valentines Day With Heart-Smart Recipes
10. Study finds racial gaps continue in heart disease awareness
11. Highmark Foundation Awards $120,000 to the American Heart Association
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2017)... ... 2017 , ... HYPERAMS, LLC announced it will perform the inventory ... Lima, Ohio. The sale began this week and the inventory is expected to sell ... uniforms, and medical accessories, including blood pressure cuffs, stethoscopes, CPR masks, as well as ...
(Date:5/28/2017)... ... May 28, 2017 , ... Viewers likely know Rob ... Emmy award-winner is also noted for his work on NBC’s The West Wing and ... host of the new series “Informed,” which puts the spotlight on important modern-day issues ...
(Date:5/27/2017)... Chicago, IL (PRWEB) , ... May 27, 2017 , ... ... dentistry. , Regardless of the talent of your dental team at presenting treatment, there ... Dental professionals invest a lot of time and money on best practices when it ...
(Date:5/26/2017)... ... May 26, 2017 , ... Mediaplanet is proud to announce ... in USA Today, which will educate readers on how to take care of all ... large focus is placed on melanoma. Dancing with the Stars professional, Witney Carson, shares ...
(Date:5/26/2017)... ... May 26, 2017 , ... ... new educational seminar to focus on current legislative activity and the latest regulatory ... at 1 p.m. Sunday, Sept. 10, and will continue through Monday, Sept. 11, ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... , May 9, 2017  Demonstrating its ... board of directors for the Pharmaceutical Research and ... for membership. Biopharmaceutical companies will now have to ... order to be eligible to join PhRMA. ... the board is sending a clear message that ...
(Date:5/8/2017)... NEW YORK , May 8, 2017 ... in the transition from fee for service reimbursement. Black ... April 2017. 1.       The Market for ... 77% of physician practices with 3 or ... Compliance Technology Solutions by Q4. "Given the magnitude of ...
(Date:5/6/2017)... , May 5, 2017  May is Stroke Awareness ... of the most important methods to prevent a stroke: ... Centers for Disease Control and Prevention, undetected and uncontrolled ... Omron, the global leader in personal heart health ... elimination of heart attack and stroke and is advancing ...
Breaking Medicine Technology: