Navigation Links
Closing hole in the heart no better than drugs in preventing strokes
Date:3/16/2012

MAYWOOD, Il. -- Loyola University Medical Center is one of the major enrollers in a landmark clinical trial that found that plugging a hole in the heart works no better than drugs in preventing strokes.

The study is published in the New England Journal of Medicine. Loyola enrolled 24 patients, one of the highest patient enrolments in the multicenter trial, and more than any other Chicago-area hospital. Principal investigators at the Loyola site are stroke specialist Dr. Michael Schneck and interventional cardiologist Dr. Fred Leya.

About 1 in 4 adults has a small hole in the wall that separates the top two chambers of the heart. It's called a patent foramen ovale (PFO). For most people, a PFO poses no problems. But in some cases, a clot can pass through the hole, migrate to the brain and trigger a stroke.

The standard treatment is medication to prevent blood clots, typically aspirin or Coumadin. A newer treatment is to plug the hole with a device delivered by a catheter. The catheter is inserted into a blood vessel at the top of the leg and guided up to the heart. When the catheter reaches the PFO, the device is deployed, opening like an umbrella to plug the hole.

The clinical trial included 909 patients who had PFOs, and had previously suffered strokes or mini strokes called transient ischemic attacks (TIAs). They were randomly assigned to receive a PFO closure device plus blood thinners or drug therapy alone.

The closure device worked no better than drugs alone in preventing recurrent strokes or TIAs. Moreover, major vascular complications occurred in 3.2 percent of the closure group.

"Medical therapy is just as good as the device," Schneck said. "The larger lesson is that we have an impetus in the United States for doing procedures without first standing back and asking all the right questions."

Leya noted the clinical trial used an older version of a closure device. "I would like to see more research to determine if better devices will have better results," he said.
'/>"/>

Contact: Jim Ritter
jritter@lumc.edu
708-216-2445
Loyola University Health System
Source:Eurekalert

Related medicine news :

1. Labopharm announces closing of US$20 million public offering of units
2. Closing the science-to-policy gap in maternal and child health in Africa
3. 1 in 5 Parents Missed Work for H1N1 School Closings: Survey
4. U.S. Nursing Home Closings Hit Poor Neighborhoods Hardest: Study
5. Closing Schools Seems to Prevent Flus Spread
6. Fear of Antidepressants Keep Many From Disclosing Depression
7. Closing in on an ulcer- and cancer-causing bacterium
8. ICU Patients at Risk for Rare Heart Rhythm Problem
9. Cook With Love This Valentines Day With Heart-Smart Recipes
10. Study finds racial gaps continue in heart disease awareness
11. Highmark Foundation Awards $120,000 to the American Heart Association
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... ... February 13, 2016 , ... Good ... the first in the area to offer AngioPlex™ Optical Coherence Tomography (OCT) Angiography, ... such as macular degeneration, diabetic retinopathy, and other vascular conditions. , In just ...
(Date:2/13/2016)... ... , ... Hidden Cypress in Sun City is the place to be on March 3rd to ... Weniger will be hosting this educational seminar from 5:30 p.m. – 7:00 p.m. Exciting ... pricing on offers. In addition, prizes will be given away and light refreshments will be ...
(Date:2/13/2016)... California (PRWEB) , ... February 13, 2016 , ... Valentine’s ... landing a date for the big day. A great outfit, flawless hair, and a ... they might as well resign themselves to a night at home with Rover. (Actually, ...
(Date:2/13/2016)... Washington, D.C. (PRWEB) , ... February 13, 2016 ... ... joined with Faces and Voices of Recovery, the leading national organization representing the ... paper urging candidates for public office to include Family Recovery in policies addressing ...
(Date:2/13/2016)... ... February 13, 2016 , ... Many individuals looking to lead a ... multitude of reasons. IsoPasta by Isolator Fitness has delved into this niche allowing ... without the high-carb repercussions. IsoPasta has 30 grams of protein and only 7 ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... N.C. , Feb. 12, 2016  Clinical Affairs leaders at ... presence in emerging areas of the world. While some companies have ... lag in their clinical activity in countries such as ... China and India ... market products in those countries. --> China ...
(Date:2/12/2016)... 2016   National Community Pharmacists Association (NCPA) ... the following statement today in response to the detailed ... Centers for Medicare & Medicaid Services (CMS) and conducted ... and others: patient advocacy organizations and ... the full CMS analysis. Our initial reaction is that ...
(Date:2/12/2016)... 12, 2016  This month,s issue of the ... takes an in-depth look at various causes and consequences associated ... drug spending, which has generated significant public outrage and ... Laura E. Happe , PharmD, MPH. --> ... PharmD, MPH. --> In 2014 prescription drug ...
Breaking Medicine Technology: