Navigation Links
Closer to an effective treatment for gum disease in smokers
Date:5/11/2009

Scientists in the USA have discovered why smokers may be more prone to chronic gum disease (periodontitis). One of the bacteria responsible for this infection responds to cigarette smoke changing its properties and the way it infects a smokers mouth.

The study published recently in the Society for Applied Microbiology journal Environmental Microbiology, showed that the bacterium Porphyromonas gingivalis adapts and changes its DNA and membrane proteins in response to cigarette smoke.

Several genes of P. gingivalis associated with its virulence (infectivity), detoxification, oxidative stress mechanisms and DNA repair are altered by exposure to cigarette smoke. As a result, the expression of a number of the proteins in the cell membrane is changed. This affects important characteristics of the bacterial cells themselves and how the immune system recognizes this pathogen.

This could explain why smokers are more likely to be resistant to treatment for periodontitis and are more susceptible to oral disease caused by infection with P. gingivalis.

Finding an effective treatment for smokers infected with P. gingivalis will be easier now that these changes in the bacterium's 'properties' have been identified.

University of Louisville researcher, Dr David Scott said: "It has long been known that smokers are more susceptible to periodontitis than are non-smokers. However, the reasons why are not so clear. Our study shows, for the first time, that components in cigarette smoke alter key characteristics of a major bacterial pathogen which, subsequently, changes how our immune system reacts to it. It may turn out that we need to develop alternate treatment plans for smokers and non-smokers".


'/>"/>

Contact: Lucy Collister
lcollister@wiley.com
44-186-547-6241
Wiley-Blackwell
Source:Eurekalert

Page: 1

Related medicine news :

1. Older Men Need to Take Closer Look for Melanomas
2. Getting Closer to Controlling Cancer Requires Funding More Laboratories and Commitment Beyond Two Years of New Stimulus, Weiner and Berg Assert in Denver Post Oped
3. UCSF Team Closer to Creating Safe Embryonic-Like Stem Cells
4. UCSF team closer to creating safe embryonic-like stem cells
5. Yale Plans Closer Look at Exercise and Cancer
6. University of Washington scientists one step closer to stopping bone loss during spaceflight
7. Scientists closer to understanding how to control high blood sugar
8. Muscular dystrophy mystery solved; Mizzou scientist moves closer to MD solution
9. Video: Pampers Together with Actress Salma Hayek Helps UNICEF Move Closer Toward Goal of Eliminating Deadly Tetanus Through Global One Pack = One Vaccine Campaign
10. Pelosi: SCHIP Vote Brings Us One Step Closer to Providing Health Care for 11 Million Children
11. Health Plans, Employers Take Closer Look at Costs and Expand Disease Management Initiatives in Response to Diabetes Prevalence Increase
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... certification process to promote standards of excellence for the field of eating disorders, ... March 22 – 25, 2018 in Orlando, Florida at the Omni Resort at ...
(Date:10/13/2017)... (PRWEB) , ... October 13, ... ... School of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, ... professionals on guideline updates for the primary prevention of cardiovascular diseases during ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , ... mock evacuation of the facility as part of a disaster drill on October 3rd. ... EMS and Shelton City Emergency Manager, as well as the Connecticut Long Term ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids ... sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited ... all ages; it is a non-competitive, non-timed event, which is all about having fun ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... --  Provista, a proven leader in the supply ... power, today announced a new resource area on Provistaco.com ... is the online home for case studies, articles on ... releases, slideshows and events. ... at their fingertips, viewers can also watch short videos ...
(Date:10/4/2017)...  South Korean-based healthcare product Development Company I.M. Lab ... Kickstarter. The device will educate the user about ,proper, ... efficiency compared to the dated and pricey CPR training ... of the compression for a more informed CPR training. ... raise $5,000. cprCUBE ...
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
Breaking Medicine Technology: