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Clinical trial volunteers mostly indifferent -- but not blind to -- researchers' financial conflicts
Date:4/4/2008

he financial disclosure, and the perceived quality of the trials research.

More than two-thirds of the respondents were not at all surprised that the researcher or institution in which he or she worked might benefit financially from the hypothetical clinical trial, with respondents least surprised to learn that researchers got a per capita payment and most surprised to learn that the researcher owned stock.

Fifty-nine percent of the study respondents felt that the possibility of financial benefit did nothing to change their trust in the researcher or the institution, although 36 percent said their trust was diminished as a result of the disclosure.

Change in trust levels was not related to the disease the person had or the severity of the disease.

A disclosure that the researcher received per capita payments was least likely to change respondents level of trustwhereas a disclosure that the researcher held an equity interest was most likely to reduce trust, the study reported.

Sugarman and his colleagues say their results, published online April 2 in the Journal of General Internal Medicine, suggest that researchers and policymakers involved in clinical trials should probably pay close attention to the impact of financial disclosures on potential study subjects.


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Contact: Christen Brownlee
cbrownlee@jhmi.edu
410-955-7832
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

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