Navigation Links
Clinical trial underway: Miniature ultrasound device could revolutionize pain relief
Date:2/18/2010

It looks more like an iPod than a medical tool. But the latest miniature ultrasound device created by Cornell biomedical engineering graduate student George K. Lewis could one day introduce a whole new level of home therapy for arthritis, injury and other painful ailments.

The sleek blue-and-white device slips into a pocket and sends ultrasound waves deep into muscles via a coin-sized polystyrene pad. This is the transducer, which converts electrical energy into ultrasound.

Lewis hopes that this model possibly the world's smallest ultrasound device can hit the marketplace and find itself in the pockets of millions of people.

Since first publishing research about his pocket-sized devices in 2007, Lewis has continued to improve them, making them smaller and more efficient. He recently teamed with MBA student Bryant Guffey to form ZetrOZ Inc. to try and take the devices to the market.

And to give the systems medical legitimacy, Lewis a National Science Foundation fellow and a Cornell Presidential Life Sciences fellow has partnered with Cary Reid, a geriatrician at Weill Cornell Medical College's Irving Sherwood Wright Center on Aging, and Charles Henderson, senior research associate in the Department of Human Development, to prepare their first clinical trial. The study will focus on osteoarthritis patients to determine whether the devices can significantly reduce joint pain. The devices are likely useful for all types of arthritis, Lewis said.

Ultrasound is often used to relieve muscle and joint pain but requires patients to receive treatments in doctors' and physical therapists' offices. Lewis' mini-machine would allow people to receive such treatment at home and work.

Reid said that medications are the primary way to treat pain in older patients, but with age comes increased risk of complications. There is a "great need" to support research into non-drug therapies for pain, Reid said.

Lewis' latest prototype sends low-intensity energy in the form of ultrasound waves from the transducer into the body, which is gentle enough to be kept close to the skin for up to 10 hours.

The clinical study at Weill Cornell will be restricted to patients with osteoarthritis of the knee. Reid emphasized that for the study to be successful, participants must not only experience reduced pain, but also increased mobility.

"The most rigorous outcome or benchmark to judge this treatment is whether people change their overall level of activity as a consequence of it," Reid said.

Lewis and Guffey also hope to eventually demonstrate that the ultrasound device could be used for such groundbreaking therapies as muscle healing and even drug delivery. For example, Lewis hopes his device can affect treatment for the brain cancer glioblastoma, which is the subject of Lewis' Ph.D. thesis. After tumor removal surgery, a surgeon would place a dissolving drug wafer into the hole, and the ultrasound would help spread the drug to kill the remaining cancer.

However, to make new claims and get FDA approval will require additional clinical studies down the road, Lewis said.


'/>"/>

Contact: Blaine Friedlander
bpf2@cornell.edu
607-254-8093
Cornell University
Source:Eurekalert

Related medicine news :

1. Radiologists encouraged to look beyond cancer for clinically unseen diseases
2. Clinical depression linked to abnormal emotional brain circuits
3. Preclinical study suggests organ-transplant drug may aid in lupus fight
4. Provectus Pharmaceuticals, Inc. Begins Phase 2 Clinical Trial for Metastatic Melanoma
5. Good Clinical Practice Journal Awards: Winners Announced
6. Microsoft Helps Developers of Clinical User Interfaces Improve Efficiency, Patient Safety With Free Toolkit
7. Study Questions Dead-End Cancer Clinical Trials
8. Genomic Health Announces Multiple Studies on Oncotype DX(TM) Presented at 2007 American Society of Clinical Oncology (ASCO) Breast Cancer Symposium
9. Clinical trials present better alternatives for dialysis patients
10. Mirixa Debuts New Clinical Technology Solutions for Enhancing Patient Care
11. IMPACT initiative looks to improve patient participation in clinical trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... ... 05, 2016 , ... In an effort to increase public ... health promotion and research organization, declared May as “National Sunshine Month.” , ... in cultural behavior over the past several decades, Americans spend more time indoors ...
(Date:5/5/2016)... ... May 05, 2016 , ... The Wisconsin ... Lombardo, PT, DPT, MA, OCS, WCS, has been selected by the Wisconsin Physical ... The WPTA Private Practice Award is awarded annually to a member of the ...
(Date:5/4/2016)... ... ... “Less than 15% of organizations nationwide can be characterized as a Certified Service ... to participate and complete the training, we are very proud to have been recognized ... we invest in volunteer engagement, we can expect $3-$6 in return.” , Points ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... interview techniques, seeks to add a deeper understanding of the program, policy or ... and each answers different yet important questions. , In a new brief released ...
(Date:5/4/2016)... ... May 04, 2016 , ... Cirius, a provider of ... innovative Secure Messaging platform, which includes secure, private messaging, large file sharing, secure ... portfolio of patents around innovative features for securing, tracking, and controlling messages for ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... May 5, 2016 Research and Markets has ... in Top 5 EU Markets"  report to their offering.  ,     ... provides information on the current Positron Emission Tomography (PET) scanner ... (T5 EU), which includes France , ... Spain and the United Kingdom ...
(Date:5/5/2016)... Research and Markets has ... Lupus Erythematosus Market and Competitive Landscape Highlights ...      (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO )  ... Lupus Erythematosus Market and Competitive Landscape Highlights ... Lupus Erythematosus pipeline products, Systemic Lupus Erythematosus ...
(Date:5/4/2016)... ZIONA, Israel , May 4, 2016 ... BVXV) announced today that BiondVax,s CEO, Dr. Ron Babecoff ... in New York City . ... 10:30am at Pioneers 2016, a conference presented by Joseph ... Palace Hotel. The BiondVax presentation that Dr. Babecoff ...
Breaking Medicine Technology: