Navigation Links
Clinical trial seeks to determine whether platelet-rich plasma can ease the pain of osteoarthritis
Date:3/22/2011

For years, doctors have used platelet-rich plasma, or PRP, to promote healing after surgery. Now, Rush University Medical Center is studying whether PRP can help relieve knee pain in patients with mild to moderate osteoarthritis.

PRP contains growth factors that promote cell proliferation and is prepared from the patient's own blood tissue. It has received popular attention recently because of its use in treating sports injuries in professional athletes, but the jury is still out on whether it is effective.

"There have been few controlled clinical trials, and results are inconsistent, but data so far suggests that it could be a promising treatment for healing in a variety of tissues," said Dr. Brian Cole, orthopedic surgeon and head of the cartilage restoration center at Rush. "The therapy will not be a cure for osteoarthritis, but it could help put off the day when a patient will need to get a knee implant." Cole is professor of orthopedic surgery at Rush University and head team physician for the Chicago Bulls.

At present, the standard of care is either corticosteroid injections, which may provide relief for about three months, or synthetic lubricants containing hyaluronic acid, which can last for up to a year.

In the double-blind, randomized, controlled study, 100 patients will receive either hyaluronic acid or PRP. The PRP is prepared from 10 millimeters of the patient's own blood. The blood is spun in a centrifuge to separate the platelets from the red and white blood cells. The platelets are then injected into the knee joint using ultrasound imaging to guide placement.

Patients will receive three injections over three weeks and will be monitored for two years. In periodic clinical exams, the physician will assess pain and knee function. In addition, a teaspoon-size sample will be taken of the synovial fluid around the knee joint to test for molecular changes that may indicate a shift in the balance of anabolic factors that increase the buildup of tissue and catabolic factors that break it down. An imbalance in these factors has been implicated in the deterioration of cartilage that leads to osteoarthritis.


'/>"/>

Contact: Sharon Butler
Sharon_Butler@rush.edu
312-942-7816
Rush University Medical Center
Source:Eurekalert

Related medicine news :

1. Jefferson clinical trial: Can a cholesterol drug prevent colon cancer?
2. Clinical trial for dry mouth funded by international oral care award
3. Revitalizing Cancer Clinical Trials -- March 21 symposium
4. Novel clinical trial aims to reduce recurrence of aggressive breast cancer
5. Clinical observation leads to lung cancer discovery
6. Study reveals security weaknesses in file-sharing methods used in clinical trials
7. UT Southwestern launches clinical trial for treatment of breast cancer using CyberKnife
8. Elsevier/MEDai enhances real-time clinical surveillance system for hospitals
9. Few physicians refer patients to cancer clinical trials
10. Older adults often excluded from clinical trials
11. New clinical trial to determine ovarian cancer risks in African-American women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2017)... ... August 22, 2017 , ... The Women’s Choice Award, a growing platform that ... the 2017 Women’s Choice Award. The identification by women of an effective new ... migraine sufferers are women. In a survey taken by the Women’s Choice Award organization, ...
(Date:8/22/2017)... ... August 22, 2017 , ... GeBBS Healthcare Solutions, a leading ... a new professional fee E/M leveling calculator tool. The new resource is offered ... E/M coding is complex which supports the need for a tool of this ...
(Date:8/22/2017)... ... 22, 2017 , ... “Without Love’s Beauty and Pleasures Life ... struggles faced while hoping for a better life. “Without Love’s Beauty and Pleasures ... who spent 13 years working with deprived/neglected adolescents and almost 20 years working ...
(Date:8/22/2017)... ... , ... “Call Of Spiritual Duty”: a revelation in an era defined by ... Growing up on the streets of North Visalia, California, Carlos Lizarde quickly became ... Biblical keys to his life, he noticed immediately that opportunities and blessings began to ...
(Date:8/21/2017)... Los Angeles, California (PRWEB) , ... August 21, ... ... Physicians is announcing the addition of two plastic surgery fellows for academic year ... is designed for candidates who have successfully completed residency in Plastic and Reconstructive ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... AVIV, Israel, Aug. 8, 2017  BioLineRx Ltd. (NASDAQ/TASE: ... immunology, today reports its financial results for the second ... achievements during the second quarter 2017 and to date: ... multiple clinical development programs for the Company,s lead project, ... 3 pivotal study with BL-8040 as novel stem cell ...
(Date:8/7/2017)... Diplomat Pharmacy, Inc. (NYSE: DPLO ) ... president, effective Aug. 7, 2017. ... other interests and will serve as president emeritus during a ... us in multiple leadership roles since he joined Diplomat with ... has provided decisive, strategic leadership which continues to benefit our ...
(Date:8/4/2017)... -- Agragen, LLC, a Cincinnati -based ... and aquacultural feed sectors, announces a significant step ... AGR131.  This drug is designed to trap and ... patients suffering from inflammatory conditions such as rheumatoid ... Biological pharmaceuticals currently used ...
Breaking Medicine Technology: