Navigation Links
Clinical trial identifies women most likely to benefit from vaginal mesh surgery
Date:3/10/2014

Certain women with vaginal prolapse are most likely to benefit from undergoing vaginal mesh surgery, a technique that has become controversial and is the focus of numerous lawsuits. The findings, which are published early online in Ultrasound in Obstetrics & Gynecology, provide valuable information regarding who should and should not be considered candidates for the surgery.

Vaginal prolapsewhen pelvic tissues weaken and the vaginal canal may protrude through the vaginal openingaffects roughly 10% to 20% of women. A significant number of patients require repeat surgeries to correct this recurring issue. They often undergo sacrospinous vaginal colpopexywhich involves attaching the vagina to surrounding tissue in the abdomen to hold it in placeor a surgical procedure that inserts a net-like implant called a vaginal mesh.

While studies suggest that vaginal mesh may reduce recurrence rates, it also has been linked with significant complications. (Indeed, vaginal mesh is the focus of a number of ongoing lawsuits.) To justify the potential complications associated with mesh use, it's important to identify women at high risk of prolapse recurrence.

Research suggests that a condition called levator avulsion is a major contributor to the development of pelvic floor prolapse and to its recurrence after surgery. This condition occurs when a woman suffers from an injury to the pelvic floor muscle during vaginal childbirth.

This information led Kamil Svabk, MD, PhD, of Charles University and General University Hospital in Prague, and his colleagues to compare sacrospinous vaginal colpopexy with vaginal mesh in patients with post-hysterectomy prolapse and levator avulsion, as diagnosed by ultrasound imaging.

The randomized clinical trial included 70 women: 36 underwent vaginal mesh surgery and 34 underwent sacrospinous vaginal colpopexy. At the one-year follow-up, ultrasound examinations revealed that there was one recurrence in the vaginal mesh group (2.8%), and 21 recurrences in the sacrospinous vaginal colpopexy group (61.8%). Dr. Svabk noted that despite the study's small size, the team was able to achieve significant results.

"By assessing patients prior to receiving treatment using pelvic floor ultrasound imaging, we are able to identify women who will benefit from vaginal mesh implantation over a conventional approach and dramatically reduce the risk of repeat surgery," said Dr. Svabk. "This is a win/win situation for our patients and for understanding the reasons behind varying success rates of conventional or less traditional treatments."


'/>"/>

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
201-748-6358
Wiley
Source:Eurekalert

Related medicine news :

1. Myriad publishes clinical utility study for Prolaris
2. UNC receives more than $40 for global clinical trials unit to treat and prevent HIV
3. Clinical opinion published on use of maternal oxygen during labor
4. REACT clinical trial supports new approach of accelerated treatment for Crohns disease
5. Cell therapy shows remarkable ability to eradicate cancer in clinical study
6. Clinical trial success influenced by biomarker- and receptor-targeted therapies in NSCLC
7. Paper examines clinical and policy implications of intimate partner violence
8. $7 million multi-institutional contract creates New York City Clinical Data Research Network
9. Cedars-Sinai clinical trial studies vaccine targeting cancer stem cells in brain cancers
10. DynaMed™ and Nursing Reference Center™ Rated Higher Than Other Point-of-Care Reference Tools in New KLAS Report on Clinical Decision Support
11. Research for Her TM, an online clinical research registry, honored with distinguished national award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2017)... ... ... “The Perfect Gift”: a customizable and interactive Bible study guide for children. “The Perfect Gift” ... She has always accepted Christ as her Savior, yet never studied His word, surrendered ... when she wrote this book to her children, so they would know the importance of ...
(Date:7/24/2017)... , ... July 24, 2017 , ... “A Short Walk ... to the Mailbox” is the creation of published author, Ed Clark. Ed Clark ... Methodist, and Christian Reformed churches as a minister of music and worship leader for ...
(Date:7/24/2017)... ... 24, 2017 , ... The Center for Addiction Recovery Training ... host a second Multiple Pathways of Recovery Conference on October 23-26, 2017. This ... from CCAR’s foundational principle – a belief in multiple pathways of recovery, aims ...
(Date:7/23/2017)... IL (PRWEB) , ... July ... ... of Eating Disorders Professionals ™(iaedp), the leading provider of education and training ... training in preparation for competency for Traditional Certification: the iaedp™ Core Curriculum. ...
(Date:7/23/2017)... ... July 23, 2017 , ... Scientists from the University of ... bursts of high-intensity, weight-bearing activity equivalent to a medium-paced run for pre-menopausal women, or ... surgeon who specializes in total spine care, I understand the importance exercise can play ...
Breaking Medicine News(10 mins):
(Date:7/5/2017)... BOTHELL, Wash. , July 5, 2017   ... a leading developer, manufacturer and marketer of proprietary clinical ... cryopreservation freeze media ("BioLife"), today announced that ... ("WAVI") its debt holder and largest shareholder, to modify ... Pursuant to the modification, WAVI agreed to ...
(Date:6/30/2017)... 30, 2017  AVACEN Medical (AVACEN) announced the publication of new ... the use of its AVACEN Treatment Method to significantly ... ... AVACEN Medical ... widespread pain. It affects approximately 200 to 400 million people worldwide according ...
(Date:6/27/2017)... Calif. , Jun 27, 2017   NuEyes ... round of funding to fuel its growth in helping the ... ODG (Osterhout Design Group), the leading developer of augmented, ... NuEyes technology sits. The undisclosed funding amount was ... capital firm, Arab Angel, with offices in Abu ...
Breaking Medicine Technology: