Navigation Links
Clinical trial for dry mouth funded by international oral care award
Date:3/16/2011

AUGUSTA, Ga. A clinical trial using an all-natural lozenge to treat dry mouth, a condition that impacts 40 percent of American adults, is under way at Georgia Health Sciences University College of Dental Medicine.

"These patients' mouths are as dry as if you've closed the faucet, and we want to turn that faucet back on," said Dr. Stephen Hsu, Molecular and Cell Biologist and co-investigator of the study. "The cells and glands that produce saliva are still there, they're just not working."

Through previous animal studies and human sample testing, GHSU researchers found that dry mouth involves salivary gland inflammation, fewer antioxidants and elevated markers for abnormal growth and DNA damage caused by free radicals. Powerful antioxidants in green tea, called polyphenols, reduce that damage to the salivary gland.

"With green tea polyphenols, we have an agent that's helping to correct the salivary gland's abnormal behavior," said Dr. Douglas Dickinson, Associate Professor in the Department of Oral Biology and co-investigator.

The team formulated an all-natural lozenge containing green tea polyphenols, xylitol and jaborandi leaf extract, a plant used in South and Central America to promote saliva production. The lozenge offers a slow, extended release only in the mouth, not the systemic effect caused by prescription dry-mouth medication, which can prompt side effects such as diarrhea and excessive sweating, said Dr. Scott De Rossi, Chairman of the Department of Oral Health and Diagnostic Sciences and principal investigator.

Sixty patients will be followed during the eight week trial, with half taking the lozenge and half taking a placebo. The four daily doses of the lozenge taken during the trial are equivalent to drinking four or five cups of green tea, which benefits overall health, the researchers added.

"I think the promise here is that patients are going to feel better and we're going to see some improv
'/>"/>

Contact: Paula Hinely
phinely@georgiahealth.edu
706-721-3646
Georgia Health Sciences University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Revitalizing Cancer Clinical Trials -- March 21 symposium
2. Novel clinical trial aims to reduce recurrence of aggressive breast cancer
3. Clinical observation leads to lung cancer discovery
4. Study reveals security weaknesses in file-sharing methods used in clinical trials
5. UT Southwestern launches clinical trial for treatment of breast cancer using CyberKnife
6. Elsevier/MEDai enhances real-time clinical surveillance system for hospitals
7. Few physicians refer patients to cancer clinical trials
8. Older adults often excluded from clinical trials
9. New clinical trial to determine ovarian cancer risks in African-American women
10. Case Western Reserve/University Hospitals join nationwide HIV vaccine clinical trial
11. Most Guidelines for Infectious Diseases Dont Come From Clinical Trial Findings
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... 2014 The NLN’s 2015 ... programs this month. Faculty have been selected through ... educators fast-tracked for administrative leadership roles within their ... for Simulation Educators, featuring a curriculum uniquely devised ... education. , Twenty nurse educators were chosen ...
(Date:12/21/2014)... In this report, the global powered surgical instruments ... application. The market, by power source, is segmented ... the market covers the handpieces; power source and ... further subdivided into drills, saws, reamers, staplers, vessel ... drivers, and others. Moreover, the power source and ...
(Date:12/21/2014)... December 22, 2014 BellasDress.com offers a ... for women. Today, it announces its BellasDress Christmas ... at its online store. , BellasDress is a famous ... to its fans through a series of promotions. The ... every customer. , “We are proud of offering ...
(Date:12/21/2014)... 21, 2014 AngelWeddingDress.com’s new collection of ... a total of 1,000 new designs in this collection, ... spring 2015. , AngelWeddingDress.com promises to provide ... with wardrobe essentials while many fashion trends come and ... customer service team at AngelWeddingDress.com is ready to assist. ...
(Date:12/21/2014)... Recently, one of the best prom dresses online ... has introduced its new collection of 2015 prom dresses, ... all its prom dresses & other fashionable designs, up ... top quality dress products and great customer services to ... of the best prom dresses online shops around the ...
Breaking Medicine News(10 mins):Health News:NLN Leadership Institute Announces 2015 Cohorts 2Health News:NLN Leadership Institute Announces 2015 Cohorts 3Health News:Global Powered Surgical Instruments Market Hit to $2.1 billion by 2019 - New Research Report by MarketsandMarkets 2Health News:Global Powered Surgical Instruments Market Hit to $2.1 billion by 2019 - New Research Report by MarketsandMarkets 3Health News:Global Powered Surgical Instruments Market Hit to $2.1 billion by 2019 - New Research Report by MarketsandMarkets 4Health News:BellasDress.com Announces its BellasDress Christmas Sale 2Health News:2015 Spring Wedding Dresses From AngelWeddingDress Just Released 2Health News:New Prom Dresses From One Of The Best Prom Dresses Online Shops, LunaDress Prom Shop 2
... 24 (HealthDay News) -- Exclusive breast-feeding of infants for ... developing the itchy skin disorder known as eczema in ... infant receives only breast milk, with no additional food ... breast-feeding up to 6 months of age is recommended ...
... York, NY, August 24, 2011 Nearly three-quarters (72%) of people ... over the last two years said that they skipped needed ... cost, according to a new Commonwealth Fund report. The ... debt, compared to about half (49%) who lost jobs but ...
... , Governments in the UK, US and Canada are undermining ... smoking, a report by public health researchers says. The paper, ... argues that films with tobacco imagery should be ineligible for ... conflict with public health goals. Earlier research shows that ...
... News) -- Accidental exposure to highly toxic chemotherapy drugs ... a new study finds. Researchers surveyed 1,339 oncology ... infusion centers and found that nearly 17 percent said ... drugs. In the United States, about 84 percent ...
... HealthDay Reporter , TUESDAY, Aug. 23 (HealthDay News) ... jobless men in what,s been dubbed the "mancession" are ... support their working partners, a small study suggests. ... conducted intensive interviews of 19 recently unemployed men. She ...
... , TUESDAY, Aug. 23 (HealthDay News) -- A common ... worsen over time and may lead to an increased risk ... diastolic dysfunction, which often comes with advancing age, the heart,s ... and is accompanied by elevated filling pressures. The new ...
Cached Medicine News:Health News:Breast-Feeding Won't Prevent Kids' Eczema, Researchers Say 2Health News:Three quarters of those who have lost jobs and health insurance are skipping needed health care 2Health News:Three quarters of those who have lost jobs and health insurance are skipping needed health care 3Health News:Three quarters of those who have lost jobs and health insurance are skipping needed health care 4Health News:Government subsidies to the US film industry promote youth smoking, argue researchers 2Health News:Nurses at Risk for Accidental Exposure to Chemo Drugs: Study 2Health News:In Tough Times, Jobless Men Embrace Housework 2Health News:In Tough Times, Jobless Men Embrace Housework 3Health News:Common Heart Dysfunction Can Help Bring on Heart Failure 2
(Date:12/17/2014)... and SAN DIEGO , Dec. 17, ... PHG ; AEX: PHIA) and Volcano Corporation (NASDAQ: ... solutions for cardiovascular applications, today announced that they have entered ... will commence a tender offer to acquire all of the ... share, or a total equity purchase price of USD 1 ...
(Date:12/17/2014)... 17, 2014  Northstar Global Business Services, Inc. ... (DTC) has made their final decision and has ... Company,s stock effective December 15, 2014, and has ... depository and book entry transfer services. All deposit restrictions ... once again fully "DTC Eligible", and has resumed ...
(Date:12/17/2014)... , Dec. 17, 2014  ImmunoCellular Therapeutics, Ltd. ... Patent and Trademark Office (USPTO) has issued a ... dendritic cell-based immunotherapeutic vaccine targeting six tumor antigens ... of US Patent No. 8,871,211, which issued October ... by administering a dendritic cell composition comprising peptide ...
Breaking Medicine Technology:Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8Northstar announces that the DTC chill on MDIN has been officially lifted 2Northstar announces that the DTC chill on MDIN has been officially lifted 3ImmunoCellular Therapeutics Announces Issuance of Key Patent For ICT-107 Cancer Vaccine 2
... ... research and biotechnology companies are testing 97 medicines and vaccines to ... report released today by the Pharmaceutical Research and Manufacturers of America ... - a global awareness campaign that originated at the 1988 World ...
... , XI,AN, China, Nov. ... a leading developer and producer,of plant extracts and pharmaceutical raw ... China, today reported that in its,third quarter, the company realized ... Revenues for the quarter ended Sept. 30, 2009 were $4,465,770, ...
Cached Medicine Technology:New Report Shows 97 Medicines and Vaccines Currently in Development for HIV/AIDS 2New Report Shows 97 Medicines and Vaccines Currently in Development for HIV/AIDS 3Huifeng Bio-Pharmaceutical Technology Reports 26% Quarterly Revenue Increase 2Huifeng Bio-Pharmaceutical Technology Reports 26% Quarterly Revenue Increase 3Huifeng Bio-Pharmaceutical Technology Reports 26% Quarterly Revenue Increase 4
... CardioSEAL is a second generation device, ... was tested in over 700 patients beginning ... of leading pediatric cardiologists who perform these ... computer simulations, on the engineering bench, and ...
... YAG laser YC-1600 is a lightweight, compact, ... and clinical performance., ,Key Features, , ... Model ,Further weight reduction has been made ... office.,, Aiming Beam Rotation ,(360 degrees ...
... delivers a solid-state green laser ... and plugs into any standard ... and extreme portability, the unit ... Nidek Phaco Emulsification System CV-24000 ...
... is an effective angina relief ... poor targets. Because it is ... the CO2 Heart Laser 2 ... timely operative decisions to revascularize ...
Medicine Products: