Navigation Links
Clinical trial finds microbicide promising as HIV prevention method for women
Date:3/5/2009

March 5, 2009 -- A clinical trial involving more than 3,000 women in the U.S. and southern Africa demonstrates for the first time the promise of a vaginal microbicide gel for preventing HIV infection in women. According to findings presented at the Conference on Retroviruses and Opportunistic Infections (CROI), one 0.5 % dose of a microbicide designed to prevent HIV from attaching to cells in the genital tract, was 30% effective. While the results are encouraging, researchers on the study, known as HPTN 035, report that additional evidence is needed to determine more definitively its effectiveness.

"These findings provide the first signal that a microbicide gel may be able to prevent women from HIV infection," says Salim S. Abdool Karim, MD, PhD, professor of clinical Epidemiology at Columbia University Mailman School of Public Health, pro vice-chancellor (research) at the University of KwaZulu-Natal in Durban, South Africa, and director the Center for the AIDS Program of Research in South Africa, who led the multi-center study for the U.S.-based Microbicide Trials Network (MTN). "Indeed, for the millions of women at risk for HIV, especially young women in Africa, there is now a glimmer of hope. But these findings also indicate that more research is needed; we can't yet say that we have an effective microbicide."

Microbicides are substances intended to reduce or prevent the sexual transmission of HIV and other sexually transmitted infections when applied topically. Several candidate microbicides are being tested in clinical trials, although none is yet approved or available for use. Earlier trials have yielded disappointing results or were stopped prematurely.

Currently, women comprise half of all people worldwide living with HIV. In sub-Saharan Africa, women represent nearly 60 % of adults living with HIV, and in several southern African countries young women are at least three times more likely to be HIV-positive than young men. In
'/>"/>

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penile extender increased flaccid length by almost a third says independent clinical study
2. Commonly Used Beauty Staple Clinically Proven to Help Treat Eczema
3. According to Frost & Sullivan, Mounting Clinical Evidence Underlines Benefits of Bone Growth and Spinal Fusion Stimulators
4. UPDATE: NewCardio Leadership to Present Clinical Data of Fully Automated QTinno(TM) Study at American College of Cardiology Annual Meeting
5. TabletKiosk Introduces the MediSlate™ MCA i1040XT: A Mobile Clinical Assistant (MCA) with Touch Screen Input
6. NewCardio Leadership to Present Clinical Data of Fully Automated QTinno(TM) Study at American College of Cardiology Annual Meeting
7. NovaBay Pharmaceuticals Announces New Preclinical Data to be Presented at the American Academy of Dermatology (AAD) 67th Annual Meeting
8. Clinical Intervention Eliminates Heel Ulcer Incidents in ICU
9. Marinus Pharmaceuticals, Inc. Announces Positive Results of its Phase 2 Clinical Trial of Ganaxolone as Adjunctive Therapy in Adults With Partial Onset Seizures
10. NanoBio to Announce Key Clinical and Preclinical Data on Its Topical Anti-infective Lotions at AAD 2009
11. VHA Selects Clinical Xpert from Thomson Reuters as its Preferred Solution for Mobile Clinical Improvement Systems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... In the past few weeks, TheBeautyPlace.com has been undergoing ... to run maintenance on our shipping facilities to update ... PR Director. "It disrupted our regular shipping schedule but ... on track after having completed the maintenance." , Now, ... which has not allowed some calls to come in ...
(Date:4/18/2015)... April 18, 2015 “ ArcAngel ” was ... takes a look at the latest and coolest ... Troohey, the host of AppWatch and technology expert, conducted the ... personal safety app. , In a turbulent world, people ... Calling 911 should always be their first move, but some ...
(Date:4/17/2015)... 17, 2015 John Evans, a Gardant ... the Patio from 2 p.m. to 3 p.m. on ... 1320 Executive Ct. in Pekin, Illinois, serves older adults ... some help to maintain their independence. , Becky Baker ... treats will be served during the luau. , For ...
(Date:4/17/2015)... Oklahoma (PRWEB) April 17, 2015 Alcohol ... Drug Dependence (NCADD) notes that drinking and driving has ... At the same time, the link between alcohol ... as domestic abuse and violence and sexual assault, and ... According to the NCADD, 5.3 million adults in America ...
(Date:4/17/2015)... In Defense of Christians (IDC) Executive ... Wednesday April 15th, the European Parliament joined its voice ... the Armenian Genocide, “paying tribute, on the eve of ... innocent Armenian victims who perished in the Ottoman Empire.” ... for this timely and needed recognition of a tragic ...
Breaking Medicine News(10 mins):Health News:TheBeautyPlace.com Temporary Number Available 2Health News:A Personal Safety Application was Featured on NewsWatch Television 2Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 3Health News:In Defense of Christians Condemns Armenian Genocide 2Health News:In Defense of Christians Condemns Armenian Genocide 3
... taken ill Wednesday after inhaling methane gas leaking from a colliery ... leak was reported early morning from the Bathdih colliery of Bharat ... ,The 10 people of Barari Basti area who fell ... to be in critical condition. ,BCCL officials have rushed ...
... the ghastly video.,A slender girl dragged along by her headlocks, on ... a torrent, then her head is smashed with a concrete ... then victorious shouts are heard. ,In the eyes ... Duaa Khalil Aswad, 17, was to love a boy from another ...
... Administration (FDA) has approved the first birth control pill ... monthly preparation of pregnancy. ,Lybrel, produced ... a low dosage of hormones ethinyl estradiol and levonorgestrel, ... pill prevents conception by halting menstrual period indefinitely. ...
... at the Albert Einstein College of Medicine in Yeshiva ... ability to use radioactivity as an energy source ... ,According to Dr. Arturo Casadevall, chair of microbiology and ... this finding could trigger a recalculation of the Earth's ...
... Sipping tea is far better than drinking water, researchers said. ... three or more cups of tea can reduce the risk ... Carrie Ruxton from King's College London, it is a wrong ... better than water as it contains antioxidants. It does not ...
... of the state-run super speciality SSKM Hospital in Kolkata was ... during a medical test Tuesday night. ,"We ... charges of outraging the modesty of this 32-year-old lady during ... told IANS. ,"A complaint was lodged by the ...
Cached Medicine News:Health News:Women in Iraq More Unsafe Than Ever 2Health News:Astronauts can Now Feed on 'radiation-eating' Fungi 2
(Date:4/17/2015)... , April 17, 2015 TWi Pharmaceuticals, Inc. ... TWi Pharmaceuticals USA , has obtained ... United States.  It has been in close contact with ... expects to have its own label specialty generic products ... the U.S. pharma market. According to IMS ...
(Date:4/16/2015)... , April 16, 2015 A drug commonly taken ... of people with multiple sclerosis (MS), according to a study ... of Neurology,s 67th Annual Meeting in Washington, DC ... "About half of people with MS experience at some point ... which the nerve carrying vision from the eye to the ...
(Date:4/16/2015)... , April 16, 2015  Amgen (NASDAQ: AMGN ... quarter financial results on Tuesday, April 21, 2015, after ... will be followed by a conference call with the ... call from Amgen will be Robert A. Bradway ... of Amgen,s senior management team. Live audio ...
Breaking Medicine Technology:Epilepsy Drug May Preserve Eyesight for People with MS 2Amgen Announces Webcast Of 2015 First Quarter Financial Results 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: