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Clinical Outcome Assessments in Early-stage Alzheimer’s Disease Clinical Trials, Upcoming Webinar Hosted by Xtalks

Studies of investigational drugs targeting the dementia stage of Alzheimer’s disease (AD) have used a co-primary approach to assess cognitive and functional (or global) measures. This approach ensured both a clinically meaningful effect by a demonstration of benefit on the functional measure and that the observed functional benefit was accompanied by an effect on the core symptoms of the disease as measured by the cognitive assessment.

As the scientific understanding of AD has evolved, enrollment of patients with AD at earlier stages where there may be no functional impairment or even no detectable clinical abnormality has become possible, as it is desirable to delay or halt disease at the earliest opportunity. Such clinical trials necessitate the use of different clinical assessments to select trial participants and/or novel endpoints to demonstrate treatment benefit, including single primary endpoints based on cognitive assessment alone.

Register for this webinar to hear three experts describe the identification and selection of clinical outcome assessments and endpoints for early (clinical stages 1 to 3) clinical trials in AD and outline strategies for optimizing their implementation through enhanced eCOA and innovative data quality programs.

Join expert speakers from Cogstate, Chris Edgar, PhD, Chief Science Officer and Edward Bartolic, PhD, Senior Director, Clinical Science, as well as Rinah Yamamoto, PhD, Principal Scientist, Clinical Ink, in a live webinar on Friday, September 10, 2021 at 11am EDT (4pm BST/UK).

For more information, or to register for this event, visit Clinical Outcome Assessments in Early-stage Alzheimer’s Disease Clinical Trials.


Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year, thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

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