Navigation Links
Cleveland Clinic Children's Hospital research suggests transmission of respiratory viruses in utero
Date:4/18/2013

The most common cause of lower respiratory tract infections in infants and young children, respiratory syncytial virus (RSV), can be transferred during pregnancy to an unborn baby, according to Cleveland Clinic Children's Hospital research published online this week in the journal PLOS ONE.

In animal models, the study shows that RSV is able to spread across the placenta from the respiratory tract of the mother to the fetus, and is present in the lungs after birth, throughout development and into adulthood. RSV is considered the primary cause of infant pneumonia and has been implicated in the development of asthma.

"Epidemiologic evidence suggests that early-life RSV infection predisposes children to recurrent wheezing and asthma," said Giovanni Piedimonte, M.D., the study's lead author and Chairman of Cleveland Clinic Children's Hospital and the Pediatric Institute. "This study challenges the current paradigm that RSV infection is acquired only after birth and shifts attention to prenatal effects of the virus, which may result in more severe and lasting consequences by interfering with an unborn baby's critical developmental processes."

Research was completed in an animal model, in which rats were inoculated with RSV during midterm pregnancy. Of those infected, RSV was found in 30 percent of fetuses, as well as in the lungs of 40 percent of newborns and 25 percent of those that reached adulthood.

Dr. Piedimonte has been the principal investigator or co-investigator of more than 30 research projects, and has authored and co-authored more than 250 journal articles, book chapters, monographs, editorials and abstracts. He holds 17 international patents and is frequently invited to speak nationally and internationally.


'/>"/>

Contact: Abbey Linville
linvila@ccf.org
216-213-2844
Cleveland Clinic
Source:Eurekalert

Page: 1

Related medicine news :

1. Cleveland Clinic research: Prior chest radiation grows risk of death after heart surgery
2. Cleveland LASIK Eye Surgeon Creates Affordable LASIK Plan for Ohio Residents
3. Cleveland Clinic's Mellen Center for Multiple Sclerosis Treatment and Research Honored for Workplace Practice that Promotes Health and Safety
4. Vein Expert in Winston-Salem, NC Participates in Elite Cleveland Clinic Seminar
5. Cleveland Clinic study shows bariatric surgery restores pancreatic function by targeting belly fat
6. Cleveland Clinic researcher receives grant to fund autism research
7. Redskins Quarterback & Lynx Shreds Athlete Kirk Cousins will Start Today vs. Cleveland Browns for Injured RG3
8. Cleveland Clinic researcher identifies 2 new genetic mutations associated with Cowden syndrome
9. University Hospitals & Philips Healthcare to showcase imaging technology at Cleveland Medical Mart
10. Cleveland Clinic study shows vitamin E may decrease cancer risk in Cowden syndrome patients
11. Cleveland Clinic researchers investigating potential drug for treatment of Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... Franklin, TN (PRWEB) , ... May 26, 2016 , ... ... today, and more than 32 million cancer survivors worldwide. On Sunday, June 5, 2016, ... the 29th annual National Cancer Survivors Day®. , National Cancer Survivors Day® is ...
(Date:5/26/2016)... ... May 26, 2016 , ... In an effort to provide hair restoration information to the ... users and those who do not use the app. Dr. Mohebi, the founder of Parsa ... Dr. Mohebi Live . , Dr. Mohebi says, “The positive response to the Snapchat ...
(Date:5/26/2016)... Texas (PRWEB) , ... May 26, 2016 , ... ... Friday, May 13 at Blackhorse Golf Club in Cypress. With the help of community ... non-profit that restores, empowers, and renews hope for wounded service members and their families ...
(Date:5/26/2016)... ... May 26, 2016 , ... Power Systems, a leading ... PowerWave Instructor Certification Course in Stoughton, Massachusetts. The course was led by Power ... the 8 hour interactive course to qualify participants as certified PowerWave trainers. ...
(Date:5/26/2016)... ... May 26, 2016 , ... The introduction of our ... PROTECTION TO YOUR HEAD ™”. , “We are proud to introduce Meghan ... football front we have Brian Quick, wide receiver for Los Angeles who was a ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... May 25, 2016 MedDay, a biotechnology ... that an oral presentation entitled "High doses of biotin in ... will be given by Professor Ayman Tourbah , Principal ... of the European Academy of Neurology (EAN) in ... disorders 3" will take place on Sunday, 29 May 2016 ...
(Date:5/24/2016)...   , ... primären Endpunkte und demonstriert Ebenbürtigkeit bei der Gesamtreinigung ... plus guter , Reinigung des ...      (Logo: http://photos.prnewswire.com/prnh/20130829/633895-a ) , ... von der MORA-Studie der Phase III für NER1006 ...
(Date:5/24/2016)... , May 24, 2016 Celsion Corporation ... development company, today provided an update on its ... clinical trial combining GEN-1, the Company,s DNA-based immunotherapy, ... of newly-diagnosed patients with advanced ovarian cancer who ... surgery.  GEN-1 is an IL-12 DNA plasmid vector ...
Breaking Medicine Technology: