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CleveMed Receives $1.23 Million in NIH Funding to Develop a System to Augment Deep Brain Stimulation Programming in Parkinson's Disease
Date:10/7/2008

CLEVELAND, Oct. 7 /PRNewswire/ -- Cleveland Medical Devices Inc. (CleveMed) announced it has been awarded $1.23 million in NIH SBIR FastTrack funding from the National Institute on Aging to develop ParkinTune(TM), a system to augment stimulator programming in deep brain stimulation (DBS) procedures for Parkinson's disease (PD). CleveMed is collaborating with clinicians at the Center for Neurological Restoration of the Cleveland Clinic Foundation, a world renowned, pioneering DBS surgery center.

"Clinical tools are needed to improve deep brain stimulation procedures and patient outcomes," said Dr. Jerrold Vitek, Director of the Cleveland Clinic Foundation Neuromodulation Research Center and grant collaborator. "Assisting neurologists by objectively capturing and tracking motor performance in response to stimulation settings with a compact wireless device should show efficacy in optimizing patient outcomes in Parkinson's disease."

DBS is a surgical procedure for treating PD motor symptoms, such as tremor, bradykinesia (slowed movements) and rigidity, when medication is no longer effective. During surgery, an electrode is implanted in a targeted location in the brain. Once inserted, the stimulator intensity, frequency and duration are programmed. This programming is also necessary in several outpatient sessions over a period of months post surgery. Each time the stimulator settings are changed the patient's motor symptoms are evaluated using the Unified Parkinson's Disease Rating Scale (UPDRS) motor exam, a subjective evaluation clinicians use to assess PD motor symptoms. The process is repeated multiple times until optimal stimulator parameters are found which minimize motor symptoms. Utilizing an automated technology platform to objectively quantify Parkinson's motor symptoms and suggest optimized stimulation settings based on those measurements may reduce the time and cost of programming sessions as well as improve patient outcomes.

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