Navigation Links
Class of Chemotherapy Drugs Helps Certain Breast Cancer Patients
Date:12/26/2007

Anthracyclines increase survival for HER2-positive tumors, but not negative ones, analysis finds,,

WEDNESDAY, Dec. 26 (HealthDay News)-- Chemotherapy drugs known as anthracyclines help boost survival for women with HER2-positive breast cancer who have undergone surgery, but they may not offer any survival benefit for those with HER2-negative tumors.

That's the conclusion of a wide-ranging analysis that pooled the results of eight randomized trials that compared the drugs with non-anthracyclines and took into account the women's HER2 status.

HER2-positive cancers test positive for a protein called human epidermal growth factor receptor 2 (HER2) and tend to grow quickly, the researchers said.

Since anthracyclines (such as doxorubicin and epirubicin) were introduced in the 1980s, they have been widely used as supplementary chemotherapy for breast cancer, said Dr. Alessandra Gennari, a medical oncologist at the National Cancer Research Institute in Genoa, Italy, and lead author of the study.

But the new analysis may change that, Gennari said. "Our study provides convincing statistical evidence that the added benefit of adjuvant chemotherapy with anthracyclines is confined to women who have breast tumors in which HER2 is overexpressed or amplified," she said.

"Since only about 25 to 30 percent of all breast cancers are HER2-positive, the vast majority of patients, with HER2-negative disease, may be spared unnecessary toxicities related to the use of this class of agents," she added.

The study findings were published online Dec. 25 in the Journal of the National Cancer Institute.

Anthracyclines have been associated with an increased risk of heart damage in some patients -- a risk doctors have known about for some time. An increased risk of leukemia, which can strike years later, is also associated with use of the drugs.

But, Gennari said, anthracyclines came into
'/>"/>

Copyright©2007 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Kingfisher Healthcare (KFH) Achieves World Class Quality Platform
2. ADDA Kicks Off AD/HD Awareness Campaign with Four Regional Conferences Beginning Sept. 29 and Series of Fall Teleclasses
3. A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
4. First Circuit Court of Appeals Rules Against Philip Morris in Lights Class Action
5. Theater Classes Help Docs Bedside Manners
6. Tarpinian: Misclassification is Theft
7. New class of RNA molecules may be important in human cancer
8. Instrumentation Laboratory Named Top of Class by Respiratory Care Managers
9. Consumer Group: Hillary Clintons Mandatory Health Insurance Purchase Plan is an Act of War on the Middle Class Family That Cant Afford $12k Policy
10. SATELLITE BROADCAST: Consumer Group Says Hillary Clintons Mandatory Health Insurance Plan is an Act of War on the Middle Class that Cant Afford $12k Policy
11. Law Offices of Howard G. Smith Announces Class Action Lawsuit Against LCA-Vision Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Class of Chemotherapy Drugs Helps Certain Breast Cancer Patients
(Date:7/11/2014)... Global enterprises today are shifting towards ... management activities. Managed services offer these global enterprises a ... slowdown resulted into rising operational costs to companies. The ... to be the global market driver for expanding the ... managed services market is estimated to grow from $142.75 ...
(Date:7/11/2014)... 11, 2014 As reported by the ... (Weintraub 7/11/14), a significant number of severe adverse events ... issues and even death from the highly-promoted and costly ... the Times report , a regulatory filing revealed ... by patients was almost 14% of prescriptions, up from ...
(Date:7/11/2014)... its kind has found that organic foods and ... conventional counterparts, including more antioxidants and fewer, less ... an unprecedented 343 peer-reviewed publications comparing the nutritional ... foods, including fruits, vegetables, and grains. The study ... between organic and non-organic foods. , "Science ...
(Date:7/11/2014)... Steven Reinberg HealthDay Reporter ... to protect children from the worldwide scourge of dengue fever ... While the vaccine only prevented dengue fever in 56 percent ... three shots, it protected more than 88 percent of them ... lead to hospitalization, and sometimes death. "This vaccine has ...
(Date:7/11/2014)... (PRWEB) July 11, 2014 Ticket Down ... Tickets at the Sleep Train Amphitheatre in Wheatland, CA. ... that can compare to what the Sleep Train Amphitheatre can ... events and special attractions over the course of its existence ... the Sleep Train Amphitheatre in Wheatland (Sacramento metro area) will ...
Breaking Medicine News(10 mins):Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 3Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 4Health News:Acthar’s Deadly Adverse Events Revealed 2Health News:Acthar’s Deadly Adverse Events Revealed 3Health News:Major study documents nutritional and food safety benefits of organic farming 2Health News:Major study documents nutritional and food safety benefits of organic farming 3Health News:Dengue Fever Vaccine Shows Some Promise in Trial 2Health News:Dengue Fever Vaccine Shows Some Promise in Trial 3Health News:Luke Bryan Tickets Sleep Train Amphitheatre in Wheatland, CA (Sacramento): Ticket Down has Slashed Ticket Prices on Luke Bryan in Wheatland at Sleep Train 2Health News:Luke Bryan Tickets Sleep Train Amphitheatre in Wheatland, CA (Sacramento): Ticket Down has Slashed Ticket Prices on Luke Bryan in Wheatland at Sleep Train 3
... ... for driving physician retention. , ... Charlotte, NC (Vocus) June 3, 2009 -- Morehead Associates will ... Physician Retention through Engagement.", , ,Retaining skilled, engaged physicians is critical to the success ...
... everyone. One of the most promising solutions is a ... wellness solution and created a stand alone program for small ... participate in behavior change programs that improve employee health. , ... pay more for employee health care than larger companies. ...
... asthma worse in patients with mild and moderate forms of ... researchers, although it may reduce the response to medications. , ... years, there has been much interest in the possible link ... Associate Professor of Medicine at National Jewish Health. "By studying ...
... , The following statement can be attributed to the American ... The American Chemistry Council (ACC) today welcomed a congressional ... its review of the scientific evidence on the safety of ... , We agree with Reps. Henry Waxman and Bart Stupak ...
... Nancy Pelosi held a press availability with Secretary of Health and ... afternoon. Below are their remarks: , , Speaker ... Secretary to the Speaker,s office. Both of us went to ... course the Secretary went there long after I was there but ...
... PDSG Integrates Data Sharing Product Portfolio , , ... Bulletin Board: PTSC) announced today that, as a result ... business into the data and information sharing solutions market, ... changed its name to Patriot Data Solutions Group, Inc. ...
Cached Medicine News:Health News:Morehead Webinar on Driving Physician Retention through Engagement 2Health News:MyWellSteps(TM) Delivers an Important Key to Healthcare Reform - Wellness Programs for Small Businesses 2Health News:Obesity does not worsen asthma, but may reduce response to medications 2Health News:American Chemistry Council Welcomes Call for Expedited FDA Review of BPA 2Health News:Pelosi Remarks Before Meeting with Secretary of Health and Human Services Kathleen Sebelius 2Health News:Patriot Scientific Corporation Announces Patriot Data Solutions Group 2Health News:Patriot Scientific Corporation Announces Patriot Data Solutions Group 3Health News:Patriot Scientific Corporation Announces Patriot Data Solutions Group 4Health News:Patriot Scientific Corporation Announces Patriot Data Solutions Group 5
(Date:7/11/2014)... 2014 Patient engagement has become a ... are turning to an assortment of marketing activities ... of this evolving approach to patient engagement, marketers ... engage patients throughout their experiences with a disease ... mapping the patient journey and employing a consumer ...
(Date:7/11/2014)... July 11, 2014  Rock Creek Pharmaceuticals, Inc. (NASDAQ: ... announced that the Food and Drug Administration ("FDA"), has ... on RCP,s Investigational New Drug ("IND") application before granting ... the US. Dr. Chris Chapman , ... comments on our IND. When we receive the agency,s ...
(Date:7/11/2014)... July 11, 2014 According ... by Composition of Material, Application (Healthcare, Homeland security, ... Product (Personal Instrument, Hand-Held Instruments, Fixed, and Installed ... to 2013 - 2020", published by MarketsandMarkets, the Scintillator Market ... 5.62% from 2014 to 2020, and reach $479.16 ...
Breaking Medicine Technology:New Study Uses Six-Step Patient Journey as Framework for Consumer-Focused Marketing Opportunities 2Rock Creek Pharmaceuticals Issues Update On US Investigational New Drug Application 2Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4
Dome shape, extra smooth tip provides safe insertion through wound & manipulation within the eye. 45, 4.0mm from end...
...
...
...
Medicine Products: