Navigation Links
City of Hope Researchers Present Data on more than 30 Studies During American Society of Hematology Meeting Dec. 5 to 8 in New Orleans
Date:12/7/2009

Topics presented range from targeting dormant cancer stem cells to assessing neurocognitive side effects after bone marrow transplants

Duarte, Calif. (Vocus) December 7, 2009 -- City of Hope researchers will present data from more than 30 studies during the 2009 American Society of Hematology (ASH) meeting Dec. 5 to 8 in New Orleans, focusing on such topics as a new drug combination to target dormant chronic myelogenous leukemia (CML) stem cells, lymphoma patients’ genetic susceptibility to therapy-related leukemia, and neurocognitive impairments after bone marrow transplants.

Research highlights include:

“Effective targeting of Quiescent CML Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate”
ASH Abstract #190 (Oral)

Imatinib mesylate (Gleevec) has become known as a wonder drug that has dramatically improved the treatment of CML, yet patients can relapse because the disease often lurks in the “quiescent” or dormant stem cells. To understand how cells resist Gleevec treatment and find ways to better target these residual stem cells, clinical research fellow and lead author Bin Zhang, Ph.D., and her City of Hope colleagues conducted a series of experiments on tumor tissue samples from patients. Research team members believe they are the first to demonstrate that histone deacetylase (HDAC) inhibitors in combination with Gleevec can destroy the hidden reservoir of treatment-resistant CML stem cells.

“We’ve shown that these drugs in combination with Gleevec are very effective in killing CML stem cells – including the dormant ones,” said

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Page: 1 2 3 4 5

Related medicine news :

1. Case Western Reserve researchers new pathway discovery published as Paper of the Week
2. Researchers find increased dairy intake reduces risk of uterine fibroids in black women
3. Wayne State Researchers Report a Possible Proofreading Step in DNA Synthesis by Observing Single Molecules of DNA Polymerase
4. Researchers identify gene that spurs deadly brain cancer
5. CWRU researchers report poor outcomes for CCI patients leaving hospitals on ventilators
6. VAI Researchers Find Long Awaited Key to Creating Drought Resistant Crops
7. Parent mentors can improve the asthmatic care of minority children, UT Southwestern researchers find
8. Researchers identify proteins in lung cancer cells that may provide potential drug targets
9. Researchers Identify Possible Causative Mutation for Crohn's Disease: Crohn's & Colitis Foundation Annual Conference to Present Emerging Research
10. Johns Hopkins researchers track down protein responsible for chronic rhinosinusitis with polyps
11. Researchers identify role of gene in tumor development, growth and progression
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
City of Hope Researchers Present Data on more than 30 Studies During American Society of Hematology Meeting Dec. 5 to 8 in New Orleans
(Date:3/2/2015)... Today the Brain Injury Association of America (BIAA) ... recognize and support the more than 5.3 million Americans who ... leads the nation in observing Brain Injury Awareness Month by ... theme for the 2015 to 2017 campaign is: Not Alone. ... educating the general public about the incidence of brain injury ...
(Date:3/2/2015)... GBCHealth, a prominent business coalition ... activities and investments in global health issues, today ... members to serve on the organization’s Board of ... Strategist and Co-founder of Partners In Health, and ... Abbasi, General Manager of Global Health and Medical ...
(Date:3/2/2015)... Los Angeles, CA (PRWEB) March 02, 2015 ... Jimmy Buffett tickets at the Hollywood Bowl . This ... can add customer appreciation promo code JIMMY-BUFFETT-2015 for added ... celebrate because their favorite performer will be headlining at ... This concert will be on Thursday, October 22nd ...
(Date:3/2/2015)... FL (PRWEB) March 02, 2015 While ... with Title VI of the Civil Rights Act, the ... and hearing loss are bringing light to the value ... statistics reveal that nearly 1 in 20 U.S. children ... in 10 in some major cities.(1) Stratus Video ...
(Date:3/2/2015)... March 02, 2015 ZoomCare announced ... remake American healthcare. Zoom will expand its Portland ... clinics and advanced care studios delivering urgent care, ... services, specialty care and outpatient surgery. With its ... to almost all healthcare needs outside of hospitalization. ...
Breaking Medicine News(10 mins):Health News:Brain Injury Association of America Launches “Not Alone” Campaign for Brain Injury Awareness Month 2Health News:Dr. Paul Farmer and Leaders from Chevron, Johnson & Johnson and Merck Join GBCHealth’s Board of Directors 2Health News:Dr. Paul Farmer and Leaders from Chevron, Johnson & Johnson and Merck Join GBCHealth’s Board of Directors 3Health News:Dr. Paul Farmer and Leaders from Chevron, Johnson & Johnson and Merck Join GBCHealth’s Board of Directors 4Health News:Dr. Paul Farmer and Leaders from Chevron, Johnson & Johnson and Merck Join GBCHealth’s Board of Directors 5Health News:Cheap Jimmy Buffett Tickets Hollywood Bowl: Ticket Down Slashes Prices on Jimmy Buffett Tickets at the Hollywood Bowl in Los Angeles/Hollywood, CA 2Health News:Stratus Video Addresses Inadequate Language Interpreting for 2.4 Million U.S. Children 2Health News:Stratus Video Addresses Inadequate Language Interpreting for 2.4 Million U.S. Children 3Health News:Stratus Video Addresses Inadequate Language Interpreting for 2.4 Million U.S. Children 4Health News:ZoomCare Announces 28-Location, On-Demand Neighborhood Health Campus 2Health News:ZoomCare Announces 28-Location, On-Demand Neighborhood Health Campus 3
... people in order to show- how eating patterns can stop you ... aged 60 or over living in many countries . They ... ate lots of green leafy vegetables, beans, olive oil, nuts and ... meat and sugar was also linked to keeping a smoother skin.// ...
... inhibitor ramipril, used for the treatment of hypertension, can ... thereby lowering the risk of stroke and myocardial infarction ... Heat Outcome Prevention Evaluation (HOPE) study showed the drug ... broad range of patients – those with normal or ...
... chronic bronchitis, research has found. It has been thought that ... survey of almost 16,000 people aged 18 to 47 ... opposite. ,The researchers found that the disease affects ... Young smokers were particularly at risk, and men were more ...
... occur in several forms, but systemic lupus erythematosus (SLE)--usually ... It is an incurable disease marked by inflammation and ... the joints, skin, heart, kidney and central nervous system. ... mistakenly attacks the body's own tissue. ,New research ...
... to believe that a gene-based treatment for heart disease may ... blood vessels in hearts with severe hardening of the arteries ... patients suffering with heart disease.// ,Treatment options for ... that open blocked arteries and improve blood flow to the ...
... A new study from Brazil has found that coffee ... blood levels of cholesterol and the protein homocysteine.High levels ... disease. Some of the compounds, called terpenoids, are known ... Right, of Marylandl University Hospital ,US, explained that "it ...
Cached Medicine News:Health News:New light on Cardiology 2
(Date:3/2/2015)... -- Edison Investment Research, a leading ... full coverage of Abzena  Highlights of ... biotech analysts Christian Glennie and Dr ... offers a range of key services and technologies ... biological products. Antitope (immunogenicity testing, protein engineering, cell ...
(Date:3/2/2015)... Mount Elizabeth Novena Hospital will soon become the first ... treat cancer using the TrueBeam™ STx system for radiotherapy ... VAR ).  At a Grand Opening event last Friday, ... of treatment including radiosurgery, a precise method of using ... from outside the body, without performing surgery.  ...
(Date:3/2/2015)... -- Valencia Technologies Corporation (" Valencia ") ... small device for the treatment of high blood pressure ... double-blinded, controlled trial are compelling and provide the Company ... succeed in a large U.S. trial for FDA approval. ... Valencia has successfully raised more than 2.2 ...
Breaking Medicine Technology:Edison Initiates Coverage on Abzena 2Mount Elizabeth Novena Hospital to Deliver First TrueBeam STx Radiosurgery Treatments in Singapore 2Mount Elizabeth Novena Hospital to Deliver First TrueBeam STx Radiosurgery Treatments in Singapore 3Valencia Technologies Implants its 48th Patient, Continues Equity Crowdfunding 2
... , RYE, N.Y., Nov. 19 Curemark LLC, ( ... focused on the treatment of neurological diseases, announced that the ... for CM-AT, its autism treatment, at three additional clinical trial ... Center in Phoenix, Arizona (SARRC); Pennsylvania State University,s Pediatric Clinical ...
... , PARIS, Nov. 19 Radiall and Integral ... medical applications, signing an agreement to confirm this new alliance. ... a long period of time, the company has established relationships ... OEMs supplying diagnostic equipment. , Integral Process is a ...
Cached Medicine Technology:Curemark Opens Patient Enrollment for Autism Treatment at Three More Clinical Trial Sites 2Curemark Opens Patient Enrollment for Autism Treatment at Three More Clinical Trial Sites 3Radiall and Integral Process Sign Agreement 2
... Trellis Infusion Catheter enables the physician to ... fluid, and disperse the agent by means ... Trellis is a multi-lumen catheter with two ... and infusion holes located between these balloons. ...
... OptiEdge offers design innovations that ensure outstanding ... handling. The biostable acrylic material of the ... the patented OptiEdge is designed to both ... of contact with the posterior capsule; and ...
... posterior chamber lenses are optical implants for ... in the visual correction of aphakia in ... The optical portion consists of a high ... have biconvex optics and supporting haptics of ...
... an intraocular lens that doesn't stop ... natural human lens, the new ACRYSOF® ... high-energy blue light. But while it ... your patient's view. That's just as ...
Medicine Products: