Navigation Links
Citicoline Supplement Doesn't Help Treat Brain Injury, Study Finds

TUESDAY, Nov. 20 (HealthDay News) -- The supplement citicoline does nothing to help improve brain function in patients with traumatic brain injury, a new study finds.

In the United States, citicoline is widely available at health food stores as a nutraceutical -- a product that reportedly provides health and medical benefits -- and is used by patients with a range of neurologic disorders.

Citicoline is also approved for treatment of traumatic brain injury, but such use had not been evaluated in a large, randomized clinical trial, noted Dr. Ross Zafonte, of Harvard Medical School, Spaulding Rehabilitation and Massachusetts General Hospital in Boston, and colleagues.

Their phase 3 clinical trial included more than 1,200 patients with mild, moderate or severe brain injuries. The patients started taking either citicoline or an inactive placebo within 24 hours of their injury and continued the therapy for 90 days.

Brain function tests conducted after the treatment period showed little difference between the two groups of patients. Rates of improvement ranged from about 35 percent to 86 percent in the citicoline group, similar to 36 percent to 84 percent observed in the placebo group.

A second evaluation, conducted six months after the brain injury, again revealed little difference between patients who took citicoline and those who took the placebo, according to the study published in the Nov. 21 issue of the Journal of the American Medical Association.

One expert said the study findings are disheartening.

The lack of any therapeutic effect "is another disappointment for individuals with traumatic brain injury," said Wayne Gordon, vice chair of the department of rehabilitation medicine at the Mount Sinai School of Medicine in New York City. He said "it highlights the fact that traumatic brain injury as an injury is not 'one-size-fits-all' and research is needed to develop approaches to the better classification of brain injury."

The study authors agreed, saying their findings suggest that the "worldwide use of citicoline for traumatic brain injury should now be questioned."

Dr. Danny Liang is a neurosurgeon at the Cushing Neuroscience Institute, part of the North Shore-LIJ Health System, in Manhasset, N.Y. He said that the new study "gives the medical community the most objective way to evaluate this potential therapy."

However, "this was a well-designed study that unfortunately gave disappointing results," Liang said.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about traumatic brain injury.

-- Robert Preidt

SOURCES: Wayne A. Gordon, Ph.D., Jack Nash Professor and vice chair, department of rehabilitation medicine, Mount Sinai School of Medicine, New York City; Danny Liang, M.D., neurosurgeon, Cushing Neuroscience Institute, North Shore-LIJ Health System, Manhasset, N.Y.; Nov. 21, 2012, Journal of the American Medical Association;Journal of the American Medical Association, news release, Nov. 20, 2012

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Fish, But Not Fish Oil Supplements, May Shield Against Stroke
2. Supplement of Red Wine Ingredient Wont Help Healthy Women: Study
3. Vitamin D Supplements Wont Help Cholesterol Levels: Study
4. Calcium, Vitamin D Supplements May Pose Risks for Men With Prostate Cancer
5. Study questions value of calcium and vitamin D supplements
6. Nothing Natural About Dietary Supplement DMAA: Study
7. Stimulant marketed as natural in sports supplement actually of synthetic origin
8. Iron supplements can reduce fatigue in nonanemic women
9. Heuer M.D. Research Announces CardiaShred™ - First Medical Doctor Formulated, Heart Healthy Weight Loss, Energy and Lean Muscle Building Supplement
10. SupplementsToWeightLoss LLC (DBA: PharmaCo Labs) and also Classe Wines LLC announced that they have signed a 5 years lease on a warehouse
11. True-Dose to Exhibit Liquid Pet Supplements at the Cardinal Health Retail Business Conference in Orlando, FL on July 11-14
Post Your Comments:
Related Image:
Citicoline Supplement Doesn't Help Treat Brain Injury, Study Finds
(Date:11/27/2015)... Wilmington, DE (PRWEB) , ... November 27, 2015 ... ... a member of the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as ... is an independent group of Microsoft Dynamics SL software users, partners, industry experts ...
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping ... platform for mental health and wellness consultation, has collaborated with a leading web-based ... the knowledge gap experienced by parents and bring advice from parenting experts within ...
(Date:11/27/2015)... ... 2015 , ... Dr. Thomas Dunlap and Dr. Patrick Coleman ... with Emergency Medicine at St., Joseph Health System’s Santa Rosa Memorial Hospital , ... in similar ways and require time-critical intervention to avoid large area heart damage and ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... in central Michigan, have come together on Thanksgiving Day to share the things ... for viewing on the Serenity Point YouTube channel, patients displayed what they wrote ...
(Date:11/26/2015)... VA (PRWEB) , ... November 26, 2015 , ... ... an American Express Travel Representative. As a franchise owner, Somu now offers travelers, ... of cruise, destination wedding packages, private cruise sales, as well as, cabin upgrades ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... , Nov. 26, 2015 ... addition of the "2016 Global Tumor ... Country Volume and Sales Segment Forecasts, Innovative ... report to their offering. --> ... of the "2016 Global Tumor Marker ...
(Date:11/26/2015)... 26 november 2015 AAIPharma Services ... geplande investering aan van ten minste $15,8 ... en het mondiale hoofdkantoor in ... resulteren in extra kantoorruimte en extra capaciteit ... groeiende behoeften van de farmaceutische en biotechnologische ...
(Date:11/26/2015)... -- --> --> Juntendo ... optimal contrast weighting of MRI for patients with Multiple ... research agreement with SyntheticMR in order to use SyMRI in ... possible to generate multiple contrast images from a single scan ... thus making it possible to both fine tune images and ...
Breaking Medicine Technology: