Navigation Links
Circulating levels of a lung protein found to be 'strongly predictive' of cardiovascular disease
Date:6/7/2011

A blood protein known as surfactant protein-D (SP-D), which is mainly synthesised in the lungs, has been described as "a good predictor" of cardiovascular disease following a large study in North America. Reporting the study online today in the European Heart Journal, the investigators said that circulating SP-D levels were clearly associated with CVD and total mortality in patients with angiographically diagnosed coronary artery disease independent of other well established risk factors (such as age, smoking, cholesterol and C-reactive protein levels).(1)

In the lungs SP-D has a role in the body's defensive response tot the many microorganisms and antigens inhaled each day, by binding to their surface and promting their clearance from the body. Blood levels of SP-D increase when the lungs are inflamed and not working well - for example, when someone catches a cold, flu or other respiratory tract infection. Blood levels also increase in those who smoke or develop a chronic lung condition such as asthma, emphysema or obstructive pulmonary disease (COPD).

In healthy people with normal lung function blood levels of SP-D are low, but when lung function is impaired (as with infections, smoking or COPD), SP-D leaks from the lungs into the blood and then into the circulation, increasing the risk of atherosclerosis.

This study aimed to determine whether or not circulating SP-D is related to cardiovascular morbidity and mortality in two independent cohorts: first, a large cohort of patients having coronary angiography for suspected coronary artery disease (CAD); and second, a "replication" cohort of ex- and current smokers with mild airflow restriction but without a known history of CVD.

"We've known for a long time that chronic lung inflammation is associated with an increased risk of cardiovascular and total mortality," said investigator Dr Don Sin from the Providence Heart and Lung Institute at St Paul's Hospital, and Univ
'/>"/>

Contact: Jacqueline Partarrieu
press@escardio.org
33-492-947-756
European Society of Cardiology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Strong evidence supports prognostic value of circulating tumor cells in breast cancer
2. UCLA researchers use nano-Velcro technology to improve capture of circulating cancer cells
3. Nanoparticles may enhance circulating tumor cell detection
4. High levels of circulating DNA may signal faster progression of lung cancer
5. Mass. General enters collaboration to develop new approach to capturing circulating tumor cells
6. Circulating tumor cells predicted recurrence, death in patients with early-stage breast cancer
7. Poor breast cancer prognosis associated with presence of circulating tumor, cancer stem cells
8. Circulating tumor cells can provide real-time information on patients current disease state
9. Circulating tumor cells correlate with poorer survival in pancreatic cancer patients
10. Survival in metastatic breast cancer directly linked to circulating tumor cells
11. Improved device provides more rapid, comprehensive analysis of circulating tumor cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2015)... (PRWEB) March 02, 2015 Today ... Luis Obispo), in partnership with the California Healthcare ... Disorders (NORD), presented an Assembly resolution recognizing Feb. ... families and healthcare professionals caring for millions of ... is a nonprofit, public policy research organization, representing ...
(Date:3/2/2015)... 2015 Today the Brain Injury Association of ... time to recognize and support the more than 5.3 million ... year BIAA leads the nation in observing Brain Injury Awareness ... March. The theme for the 2015 to 2017 campaign is: ... platform for educating the general public about the incidence of ...
(Date:3/2/2015)... March 02, 2015 A cocaine ... deviating from the typical nip slip or scathing scuffle. ... industry is dawning the streets of Hollywood as Paper ... about drug addiction and substance abuse in Hollywood. The ... to take a political stance on the travails of ...
(Date:3/2/2015)... “ Wants and Needs ” was ... which features the latest and coolest mobile applications on ... mobile technology expert and host of NewsWatch, conducted the ... helps people evaluate priorities. , Whether a person needs ... Needs app. The app allows people to enter and ...
(Date:3/2/2015)... OR (PRWEB) March 02, 2015 ... plan to remake American healthcare. Zoom will expand ... 28 neighborhood clinics and advanced care studios delivering ... health, emergency services, specialty care and outpatient surgery. ... on-demand access to almost all healthcare needs outside ...
Breaking Medicine News(10 mins):Health News:California Healthcare Institute Spotlights Impact of Rare Diseases with Assemblymember Katcho Achadjian 2Health News:California Healthcare Institute Spotlights Impact of Rare Diseases with Assemblymember Katcho Achadjian 3Health News:Brain Injury Association of America Launches “Not Alone” Campaign for Brain Injury Awareness Month 2Health News:Oscar Statue Snorting Cocaine Catches All Eyes in Hollywood, Ca 2Health News:Oscar Statue Snorting Cocaine Catches All Eyes in Hollywood, Ca 3Health News:An Application to Evaluate Priorities Was Featured on NewsWatch Television on January 30, 2015 2Health News:ZoomCare Announces 28-Location, On-Demand Neighborhood Health Campus 2Health News:ZoomCare Announces 28-Location, On-Demand Neighborhood Health Campus 3
... HealthDay Reporter , WEDNESDAY, July 6 (HealthDay News) ... and linked to increased rates of potentially dangerous low ... drug was approved in 2001 to help heart failure ... severe shortness of breath. But the drug had no ...
... expanded access to health care facilitated by health care reform ... and other advanced medical professionals. According to a study published ... American College of Surgeons, the United States will face ... nurses, and physician assistants over the next two decades. The ...
... WEDNESDAY, July 6 (HealthDay News) -- Simpler and shorter ... in millions of people worldwide infected with the bacterium ... researchers report. TB, or tuberculosis, is the leading ... virus that causes AIDS. About half a million people ...
... , WEDNESDAY, July 6 (HealthDay News) -- Move over, Lyme ... parts of the country, and this one can kill. ... parasite that attacks blood cells, causing flu-like symptoms that can ... is caused by bacteria, babesia microti parasites are carried by ...
... in The Journal of Sexual Medicine reveals ... physical inactivity, high alcohol consumption, tobacco smoking, and hard ... an unhealthy lifestyle is more common in persons who ... Frisch, MD, PhD, DSc, of Statens Serum Institut, used ...
... Ga. Altering the body,s metabolism could be an ... The finding that inhibiting heat shock transcription factor 1, ... another wake-up call that a low-fat, healthy diet is ... Virologist/Immunologist at Georgia Health Sciences University. HSF1 and its ...
Cached Medicine News:Health News:Study Finds Heart Failure Drug Ineffective 2Health News:Study Finds Heart Failure Drug Ineffective 3Health News:Study Finds Heart Failure Drug Ineffective 4Health News:Future labor shortfalls of medical professionals predicted due to new demands of health-care reform 2Health News:New Combo Therapy May Prevent TB, Save Lives in People With HIV 2Health News:A Deadly New Reason to Avoid Deer Ticks 2Health News:A Deadly New Reason to Avoid Deer Ticks 3Health News:An unhealthy lifestyle is associated with sexual dysfunction 2Health News:Transcription factor is potential target for liver cancer treatment 2
(Date:3/2/2015)... 2, 2015   Oriel STAT A MATRIX ... covering the most critical compliance and performance issues ... device manufacturers are experiencing an industry-transforming level of ... products, and global supply chains are negatively impacting ... and global regulators are increasing compliance requirements, scrutiny, ...
(Date:3/2/2015)... 2015  Kush Bottles, North America,s ... for the marijuana industry, announced today that its CEO ... nominated for a 2015 Excellence in Entrepreneurship Award.  ... is designed to recognize individuals who exemplify the ... creativity and determination, have established and nurtured successful ...
(Date:3/2/2015)... , March 2, 2015  Maquet Medical ... that it has signed an exclusive distribution agreement ... Medical,s flagship product, the Flight 60 mechanical ventilator. ... technology, providing dependable and affordable mobility. Starting in ... will be sold in the United ...
Breaking Medicine Technology:Oriel STAT A MATRIX Announces New Professional Certification Programs for Medical Device Regulatory and Quality Assurance Professionals 2Oriel STAT A MATRIX Announces New Professional Certification Programs for Medical Device Regulatory and Quality Assurance Professionals 3Kush Bottles CEO, Nicholas Kovacevich, Nominated for 2015 "Excellence in Entrepreneurship Award" 2Maquet Medical Systems USA to Exclusively Distribute Flight Medical's Flight 60 Respiratory Ventilators 2Maquet Medical Systems USA to Exclusively Distribute Flight Medical's Flight 60 Respiratory Ventilators 3
2.0mm Rounded Tip, 12mm From Tip to Bend Gently Curved, 15mm Shaft; In Titanium...
0.5X2.0mm Tip, Oval Shape; in Titanium....
Bend with "H" Shaped Tip, LEFT; in Titanium....
Lightly Curved-Blunt Tips Rounded Blades; 1mm Eye in Blades; 27mm from mid screw to tip. Matte finish; Stainless Steel, overall length 120mm...
Medicine Products: