Navigation Links
Circulating Tumor Cells Reveal Insights Into Lung Cancers
Date:7/2/2008

Technology could one day help tailor treatments to individual patients, study says

WEDNESDAY, July 2 (HealthDay News) -- A new technique for finding and analyzing stray cancer cells in the blood of lung cancer patients may make it possible for doctors to one day not only determine the genetic "signature" of particular tumors but to monitor changes in those cells and adjust treatments accordingly.

"I think this is key to personalized medicine," said Dr. Daniel Haber, senior author of a paper detailing the technology, to be published in the July 24 issue of the New England Journal of Medicine but released early online Wednesday. "As we get to targeted therapies in increasing numbers, and increasing understanding about the genetics that guide targeted therapies, we need a way to know what we're treating."

The "CTC chip" technology described in the new paper may also one day aid in the detection of cancers that are likely to spread. "This is an early warning sign we could use for earlier detection," said Haber, who is director of the Massachusetts General Hospital Cancer Center in Boston.

A previous study published in Nature used the CTC (Circulating Tumor Cells) chip technology to look at CTCs in lung, pancreatic, prostate, breast and colon cancers. The CTC chip successfully found such cells in 99 percent of the samples.

"We're very interested in the biology of these cells because no one has really been able to study metastasis [spread of cancer to other parts of the body] in action," Haber said. "These are the cells that cause metastases and the lethality of cancer. Now that we can identify and purify them in decent numbers, we can study and hopefully identify some of their vulnerabilities. It opens up a whole field of human metastasis and human therapies."

The CTC chip is a silicon chip about the size of a business card that has 80,000 "columns" coded with an antibody that acts li
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine news :

1. Circulating fats kill transplanted pancreas cells, study shows
2. FDA Clears Cellsearch(TM) Circulating Tumor Cell Test for Monitoring Metastatic Prostate Cancer Patients
3. High circulating D-dimers are associated with presence of ascites
4. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
5. Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells
6. Study details regulation of vital tumor suppressor gene p53
7. Human C-reactive protein regulates myeloma tumor cell growth and survival
8. Customized virus kills brain tumor stem cells that drive lethal cancer
9. Study suggests brain tumors need treatment with multiple targeted drugs
10. Bright tumors, dim prospects
11. National Brain Tumor Foundation Unites with BrainLAB in Support of Patient Education
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/4/2009)... , PALO ALTO, Calif., Dec. 4 /PRNewswire-Fi...announced today that its Board of Directors has se...for February 11, 2010 with a record date of Decemb...e Plaza Cabana Hotel, 4290 El Camino Real, Palo Al...will be webcast by Thomson Financial and can be ac...
(Date:12/4/2009)..., NEW YORK, Dec. 4 Thousands of ...ffices nationwide today, to participate in a commu...nd advisory firm,s support for literacy with chari...flects our firm,s long history of volunteerism. In...n the spirit of caring to brighten the holidays fo...
(Date:12/4/2009)..., PEMBROKE, Bermuda, Dec. 4 /PRNewswire-Firs... Ltd (NYSE: AWH ) today announced that Scott Car... Jack Sennott, Executive Vice,President and Chief ...the 2009,Goldman Sachs U.S. Financial Services Con... Center in New York City on Tuesday, December 8, 2...
(Date:12/4/2009)..., SCOTTSDALE, Ariz., Dec. 4 Health...d, non-traded, real estate investment trust, annou...t to acquire a three building medical office portf...s, and Fort Wayne, Indiana for approximately $20,5... to the satisfaction of a number of conditions. ,...
(Date:12/4/2009)... , MADISON HEIGHTS, Mich., Dec. 4 /PRNewsw...ew Committee of BetterInvesting Magazine today a...bruary 2010 "Stock to Study" and C.R. Bard, Inc. ...Stock" for investors, informational and educationa... of growth opportunities involving its flagship dr...
Breaking Medicine News(10 mins):Health News:Varian Medical Systems Schedules Annual Stockholder Meeting in Palo Alto 2Health News:KPMG Employees Provide 'Holiday Bear Hugs' and Books in Firmwide Service Day for Children 2Health News:Allied World to Present at the 2009 Goldman Sachs U.S. Financial Services Conference 2Health News:Healthcare Trust of America, Inc. Executes Agreement to Acquire a 92,500 Square Foot Medical Office Portfolio Located in Texas and Indiana 2Health News:BetterInvesting Magazine Releases February Stock to Study and Undervalued Stock Choicesfor Investors' Informational and Educational Use 2
...ay,September 15, will mark the first national "Sho...on, MD-based nonprofit patient advocacy,group, wil...ington, DC to,celebrate. From noon to 2 pm at Port...vent is free but donations are,requested. More inf...
...nic Obstructive Lung Disease (GOLD) has released n...vention of chronic obstructive pulmonary disease (...portance of proper diagnosis, assessment of the di...ine, but this is the first complete makeover since...
...in Access To Premier Research Platform Cus...s, CHENNAI, India, Sept. 14 Thomson Scientific,p...TOC) and leading provider,of information solutions...son Scientific,s ISIWeb of Knowledge,platform to s...
...ast 10 years at the huge TAS rotorcraft ...TH, Texas, Sept. 13 Texas Aviation Services, an,i...on, MRO and maintenance,services for over 36 years...show (Air Medical Transport Conference,sponsored b...
...coated model is safer , , THURSDAY, Sept. ...coated stents finds that those coated with the med... those coated with another drug, paclitaxel. , Ana... at the entire picture," said lead researcher Dr. ...
...ernational,Inc. (Nasdaq: ARRO ) today sent anothe... on the WHITE proxy card for its planned $45.50 me...to re-elect the Arrow Board of,Directors, who are ... The Annual Meeting is on September 20, 2007. The...
Other Medicine News:Health News:DC Psoriasis Event Saturday Will Celebrate First National Short Sleeve Day 2Health News:Updated GOLD report presents new understandings in diagnosis, treatment and prevention of COPD 2Health News:Thomson Scientific Signs Multi-Year Agreement with The Council for Scientific and Industrial Research (CSIR) 2Health News:Thomson Scientific Signs Multi-Year Agreement with The Council for Scientific and Industrial Research (CSIR) 3Health News:Texas Aviation Services: Over 20 Years of Creating 'Flying Emergency Rooms' for Airborne EMS Customers in US and Latin America 2Health News:Drug-Coated Stents Go Head to Head 2Health News:Drug-Coated Stents Go Head to Head 3Health News:Arrow International Sends Letter Reminding Shareholders to Vote White Proxy Card in Support of Teleflex Merger and Election of Current Board of Directors 2Health News:Arrow International Sends Letter Reminding Shareholders to Vote White Proxy Card in Support of Teleflex Merger and Election of Current Board of Directors 3Health News:Arrow International Sends Letter Reminding Shareholders to Vote White Proxy Card in Support of Teleflex Merger and Election of Current Board of Directors 4
(Date:12/4/2009)..., Opposes use of imported drugs often stored .... 4 Today, the senior a...t the Dorgan Importation plan encompassed in SA 27...ator Dorgan,s importation amendment is poised to o...stem to be breached, and our health to be endanger...
(Date:12/4/2009)... , MORRISTOWN, N.J., Dec. 4 /PRNewswire-First... ), a leading global specialty pharmaceutical comp...aboratories, Inc.-Florida, filed an Abbreviated Ne...rug Administration seeking approval to market its ... patent owned by Takeda Pharmaceutical Company Lim...
(Date:12/4/2009)... , RARITAN, N.J., Dec. 4 Depre...on Deficit Hyperactivity Disorder (ADHD), sleep di...ties reported to occur more often in people who sa...ose without an epilepsy diagnosis, according to a ...the U.S. ,, Findings from " CNS-Related Comorbi...
Breaking Medicine Technology:RetireSafe Urges Senate to Defeat Senate Amendment 2793 -- Says Senator Dorgan's Drug Importation Plan Puts Seniors at Risk 2Watson Files FDA Application for Generic Rozerem(R) 2Watson Files FDA Application for Generic Rozerem(R) 3Looking Ahead to AES 2009: New Insights on Comorbidities and Other Considerations for Epilepsy Treatment 2Looking Ahead to AES 2009: New Insights on Comorbidities and Other Considerations for Epilepsy Treatment 3Major clinical study rejects cancer safety fears of most common heartburn treatment 56590 1Major clinical study rejects cancer safety fears of most common heartburn treatment 56590 2Lead in bone associated with increased risk of death from cardiovascular disease in men 56585 1Lead in bone associated with increased risk of death from cardiovascular disease in men 56585 2Getting plants to rid themselves of pesticide residues 9840 1
... 2007 /PRNewswire-FirstCall/ --,Genzyme Corp. anno...ase 3 clinical studies to assess the safety and ef...n-antibiotic, polymer,therapy for patients with Cl...e second Phase 3 study of tolevamer liquid is full...r. , In this first Phase 3 study known as the Poly...
...ESS WIRE)--Jul 9, 2007 - ZIOPHARM,Oncology, Inc. (...,from an ongoing phase II trial of ZIO-201 (isopho...a patients was presented at the,European Society o...007 in Lugano, Switzerland. The abstract entitled,...rcoma," was presented by,Rashmi Chugh, MD, a Princ...
Other Medicine Technology:Genzyme Announces Data from First Phase 3 Study of Tolevamer in,Patients with C. difficile Associated Diarrhea 2Genzyme Announces Data from First Phase 3 Study of Tolevamer in,Patients with C. difficile Associated Diarrhea 3Genzyme Announces Data from First Phase 3 Study of Tolevamer in,Patients with C. difficile Associated Diarrhea 4Positive ZIO-201 Interim Phase II Sarcoma Data Presented at,European Society for Medical Oncology 2Positive ZIO-201 Interim Phase II Sarcoma Data Presented at,European Society for Medical Oncology 3
Heavy Duty Locking Pliers
Delicate Wire Cutter
Osteotome
...tomap is the companys core product. It is created ...l eye care for the screening of eye and non-eye di...-patient examination basis and is non-reimbursable...ital wide-field of view of the patients retina whi...
Medicine Products: