Navigation Links
Circassia Announces Successful Results From Phase II Clinical Study of ToleroMune(R) Cat Allergy Therapy
Date:11/20/2009

OXFORD, England, November 20 /PRNewswire/ -- Circassia Ltd, a specialty biopharmaceutical company focused on allergy, today announced positive results from a recently completed phase II clinical study of its ToleroMune(R) cat allergy therapy, which successfully identified the optimal dosing regimens to progress into late-stage development. The clinical trial, which was the first of its kind in the field of cat allergy immunotherapy, showed that Circassia's ToleroMune treatment was extremely well tolerated and greatly reduced sufferers' symptoms.

Circassia conducted the double-blind study in Canada, where 121 subjects with confirmed cat allergies were randomised to receive placebo or one of four different treatment regimes with standardised doses of ToleroMune. The volunteers were exposed to cat allergens (aerosolised dander) in an environmental exposure chamber for 3 hours each day on four consecutive days, both before and after treatment. At set time points the subjects scored their ocular and nasal symptoms to allow investigators to measure the effect of the ToleroMune treatment. This is the first trial of a cat allergy immunotherapy to use this validated approach.

The study's results demonstrate that ToleroMune therapy can dramatically reduce both nasal and ocular allergy symptom levels, and that the treatment effect grows as the duration of exposure increases and symptoms are at their greatest. The optimal regimen decreased total symptom scores by 67% compared with placebo. Throughout the study ToleroMune treatment was extremely well tolerated, with a safety profile similar to placebo. This contrasts with many traditional immunotherapies, which are associated with a range of local tolerability issues and sometimes severe and even life-threatening adverse events.

"These positive phase II results are extremely important for Circassia as they identify the optimal treatment regime to move into the final stages o
'/>"/>

SOURCE Circassia Ltd
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. IVF Florida Announces New Patient Finance Solution for Fertility Treatments
2. Secretary Shinseki Announces Study of Vietnam-Era Women Veterans
3. Great Customer Service Just Got Better as Emedco Announces the Launch of their Completely Updated and Enhanced Website
4. Nationwide Imaging Services, Inc., Leader In Diagnostic Imaging Equipment, Announces The Creation Of New Business Division Nationwide Medical Equipment Services
5. Parascript Announces AccuDetect 3.0 Computer Aided Detection (CAD) Algorithms With Improved Performance for CAD Vendors and Manufacturers of Mammography Systems
6. Universal Health Services, Inc. Announces Stock Split and Cash Dividend Increase
7. GettingHired Announces Additional Funding for Continued Growth as Well as R&D of New Product for Long Term Disability and Workers Comp.
8. Ziosoft Announces the Appointment of Rob Royea, Vice President, Sales and Marketing
9. WAT-AAH!, The First Functional Bottled Water For Kids, Announces The Release of WATs-THE-WORD?!
10. Oncolytics Biotech(R) Inc. Announces Terms of Unit Offering
11. Albireo Announces Positive Clinical Data on A3309 in Patients with Chronic Idiopathic Constipation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... According to a new market report published by ... Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 ... at USD 1,531.2 million in 2013 and is expected ... to 2019, to reach an estimated value of USD ... market is witnessing significant growth due to increasing R&D ...
(Date:8/21/2014)... HealthDay Reporter THURSDAY, Aug. 21, 2014 ... sex with a regular partner, straight women still lag ... Using surveys of single people, the Kinsey Institute research suggests ... percent of the time during sex, while lesbians do so ... achieving orgasm during about 63 percent of sexual encounters. ...
(Date:8/21/2014)... do not protest being overcompensated, even when there ... Brains and Behavior Program have found. , This ... previously believed about the inequity of others, researchers ... Brain Connectivity . These findings suggest humans, ... indicating the interest humans show in others, outcomes ...
(Date:8/21/2014)... New York (PRWEB) August 21, 2014 ... Market Research "Enteral Feeding Devices Market (Enteral Feeding Tubes, ... Syringes) - Global Industry Analysis, Size, Share, Growth, Trends ... market was valued at USD 2.0 billion in 2012 ... USD 3.1 billion in 2019growing at a CAGR of ...
(Date:8/21/2014)... A mindfulness-based therapy for depression has the added ... see their family doctors, according to a new study ... and the Institute for Clinical Evaluative Sciences (ICES). ... who received mindfulness-based cognitive therapy showed a significant reduction ... compared with those who received other types of group ...
Breaking Medicine News(10 mins):Health News:Global Microfluidic Device System Market: Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 2Health News:Global Microfluidic Device System Market: Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 3Health News:Study: Men, Lesbians More Likely to Have Orgasms 2Health News:Study: Men, Lesbians More Likely to Have Orgasms 3Health News:Influenced by self-interest, humans less concerned about inequity to others 2Health News:Influenced by self-interest, humans less concerned about inequity to others 3Health News:Enteral Feeding Devices Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 2Health News:Enteral Feeding Devices Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 3Health News:Enteral Feeding Devices Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 4Health News:Mindfulness-based depression therapy reduces health care visits 2
... prostate specific antigen levels than men of normal weight. // ... not be as good at identifying early prostate cancer in ... evidence of prostate cancer. Results showed PSA levels declined as ... and throughout all races. A study done in 2003 showed ...
... not be the only thing diabetics need to do ... // say researchers based on findings of a recent ... blood pressure, is found to exacerbate the condition. ... markedly decrease the risk of neuropathy, however they also ...
... use of alternative or complementary therapies have increased over ... using // at least one form of alternative medicine. ... yoga, hypnosis, acupuncture, chiropractic care, and high-dose vitamins. ... own survey taken in 1997 to the National Health ...
... more folate are less likely to develop high blood pressure ... For the study researchers analyzed data from two large ... gave the women questionnaires, which asked about their folate and ... blood pressure at the start of the study. It was ...
... follow a heart-healthy diet and weight-loss regimen may get ... HDL (high-density lipoproteins or "good" cholesterol) levels, according to ... than 76 with low HDL and known coronary artery ... diet and lost weight. However, results showed those who ...
... sex hormones could be responsible for some of the ... ,After measuring levels of five different sex hormones in ... to those found in healthy people. All the MS ... and brain damage characteristic of the disease. ,Results ...
Cached Medicine News:
(Date:8/20/2014)... , Aug. 20, 2014  The National ... the latest results achieved by the real-time, pseudoephedrine ... the National Precursor Log Exchange (NPLEx), automatically blocks ... track down meth offenders and make arrests. Data ... Kentucky blocked the sale of ...
(Date:8/20/2014)...  The National Association of Drug Diversion Investigators ... the real-time, pseudoephedrine (PSE) blocking system in Missouri. The ... (NPLEx), automatically blocks unlawful pseudoephedrine sales and helps ... make arrests. Data released by NPLEx shows electronic ... the sale of more than 19,030 boxes of medicine ...
(Date:8/20/2014)... -- PTC Therapeutics, Inc. (NASDAQ: PTCT ) today ... - FBR 1 st Annual Healthcare Conference ... on Wednesday, September 3 rd - Citi,s 9 ... on Thursday, September 4 th In ... of America Merrill Lynch Global Healthcare Conference at the Bank ...
Breaking Medicine Technology:Kentucky's Stop-Sale System Achieves Significant Results In Battle Against Meth 2Missouri's Stop-Sale System Achieves Significant Results In Battle Against Meth 2PTC Therapeutics to Participate at Upcoming Investor Conferences 2
... , MINNETONKA, Minn. , July 14 ... a leading provider of world-class devices and therapies for both ... prospective, multi-center study on their market leading MiniArc Single-Incision Sling ... concludes that MiniArc efficacy rates for negative cough stress test ...
... CINCINNATI , July 14 Kendle (Nasdaq: KNDL ) announced today ... Wednesday, Aug. 4, 2010 . The Company will host a telephone conference call and simultaneous ... question and answer session will follow. , , ... , , , ...
Cached Medicine Technology:12-Month Study Reports 90% Success Rate for AMS' MiniArc Single-Incision Sling 212-Month Study Reports 90% Success Rate for AMS' MiniArc Single-Incision Sling 3Kendle Announces Details Regarding Second Quarter 2010 Earnings Conference Call and Webcast 2Kendle Announces Details Regarding Second Quarter 2010 Earnings Conference Call and Webcast 3
Redesigning the World's Oxygen Therapy One Device at a Time. , ,Everything you like about our OXYMATIC 400 Series conservers, only better!...
... Accutrol is similar in design to the ... incorporates a temperature probe at the tip ... can accurately determine the patient's core body ... accuracy comparable to a pulmonary artery catheter ...
... Ultra Micro Shafts For Insertion Through ... For Light-Weight ... ,Curved Shafts For A More Comfortable Approach., ... ,Protective Cap Supplied For Protection Of Jaws ...
The New Easy-To-Use Disposable Diamond Knife Cleaning System Can Remove Even Baked-On Debris In Seconds. It Is Much More Effective Than Steam Or Blocks Of Styrofoam, Much Safer For Employees As Wel...
Medicine Products: