Navigation Links
Circadian clock may impact organ transplant success
Date:10/4/2011

w and the study's first author.

While the researchers can determine whether clock gene expression is up, down or mutated, there is currently no way to do the tests in humans. Until screening tests are identified, donors could be screened for signs of dysfunction such as a sleep disorder or even aberrant behaviors that can impair healthy clocks, such as shift work, Rudic said. "Ideally this will open up some new research avenues," he said.

Interestingly, when blood vessels from the mutant mouse stay in that mouse, disease progression is much slower. "We believe that bad clock function worsens when it intersects with disease, so if you are eating a high-fat diet or if you undergoing a serious surgery like a transplant, and you have a bad clock, disease may occur and may occur quickly," Rudic said.

In 2009, he reported in the journal Circulation that mice with mutated or missing clock genes were prone to vascular disease similar to smokers and people with high blood pressure and cholesterol. That study showed the blood vessel clocks regulate key signaling that enables blood vessel dilation and remodeling.


'/>"/>

Contact: Toni Baker
tbaker@georgiahealth.edu
706-721-4421
Georgia Health Sciences University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study shows new evidence of age-related decline in the brains master circadian clock
2. Rising star of brain found to regulate circadian rhythms
3. How cancer cells loose their (Circadian) rhythm
4. Researchers work to turn back the clock on bone-producing stem cells
5. Winding back the clock with kidney stem cells
6. Biological clock ticks slower for female birds who choose good mates
7. Bodys Clock Gene May Play Role in Depression
8. As Clocks Fall Back on Sunday, Think About Better Sleep
9. Temperature rhythms keep body clocks in sync, UT Southwestern researchers find
10. Ticking biological clock increases womens libido, new research shows
11. Turning back the cellular clock
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... published today in the online journal PLoS Outbreaks ... West Africa by the end of the month if ... State University and Harvard University researchers also discovered through ... significantly increased in August in Liberia and Guinea, around ... place, indicating that the mass quarantine efforts may have ...
(Date:9/19/2014)... NY (PRWEB) September 20, 2014 As summer ... Krishnan DMD in Queens, NY now reminds area patients about ... than 80% of our population affected by gum disease, there ... longer.” , For over 20 years Dr. Krishnan has treated ... Hills office location. “Most patients that come in due to ...
(Date:9/19/2014)... led by Medical College of Wisconsin (MCW) scientists has identified ... in rats, mice and in humans. The findings are published ... , Leah Solberg Woods, Ph.D., associate professor of pediatrics ... Wisconsin Research Institute, led the study and is the corresponding ... identified a gene called Tpcn2 in which a variant was ...
(Date:9/19/2014)... 19, 2014 Capital Region Periodontics ... is excited to announce the latest addition to ... gingivitis and those needing dental implants. Often referred ... treatment removes the fear factor normally associated with ... discomfort and bleeding make, this procedure a very ...
(Date:9/19/2014)... researchers say a simple test that combines thinking ... for developing Alzheimer,s disease in a person, even ... dementia., Faculty of Health Professor Lauren Sergio and ... asked the participants to complete four increasingly demanding ... computers. The test aimed at detecting the tendency ...
Breaking Medicine News(10 mins):Health News:Research predicts possible 6,800 new Ebola cases this month 2Health News:New York Periodontist Dr. Prabha Krishnan Now Raises Awareness about the Dangers of Untreated Decay, Gingivitis and Gum Disease During Self-Awareness Month 2Health News:New York Periodontist Dr. Prabha Krishnan Now Raises Awareness about the Dangers of Untreated Decay, Gingivitis and Gum Disease During Self-Awareness Month 3Health News:Albany, NY Periodontist Reed Ference, DMD, Calms Fears of Patients with Gum Disease by Offering LANAP®, An Advanced, Less Invasive Treatment Solution 2Health News:Albany, NY Periodontist Reed Ference, DMD, Calms Fears of Patients with Gum Disease by Offering LANAP®, An Advanced, Less Invasive Treatment Solution 3Health News:Simple test can help detect Alzheimer's before dementia signs show: York U study 2
... survey conducted in US in 2002 and observed that half of ... have had previous ones earlier. ,Women who had come ... 30, were from a large family and with low income. Most ... conceived in spite of it. ,Abortions are not uncommon ...
... South Korea has caused Japan to temporarily suspend the ... around 6000 chickens have died as a result of ... outbreak have been sought from South Korea. "As a ... Korean poultry", Chief Cabinet Secretary Yasuhisa Shiozaki of Japan ...
... of botulism following cosmetic injections to the face indicates ... that resulted in toxin levels up to 40 times ... ,Botulism is a rare paralytic illness caused by ... toxin-producing strains of Clostridium baratii and Clostridium butyricum. Botulism, ...
... a cheap and simple way of cutting heart disease ... to a study by heart experts, folic acid could ... blood considered to be a cause of cardiovascular disease, ... from the London School of Medicine and Barts Hospital, ...
... Two recent articles in Science by researchers at Yale School ... the risk of developing //the aggressive 'wet' form of age-related ... people over age 50. ,AMD causes light-sensitive cells ... of central vision. Of the two forms of AMD, the ...
... for Ageing, Senator Santo Santoro, to discuss the issue of ... AMA's Federal Budget Submission 2007-08. ,The current ... difficult for GPs to provide ongoing care to residents of ... Haikerwal, said today the number of general practitioners able to ...
Cached Medicine News:Health News:Highly-Concentrated Botulinum Preparation Can Result in Severe Illness 2Health News:Highly-Concentrated Botulinum Preparation Can Result in Severe Illness 3Health News:Gene Linked With Aggressive 'Wet' Form Of AMD 2
(Date:9/19/2014)... According to market research ... Industrial, & Laboratory), Industry (Food, Pharmaceutical, Biotechnology, Surgical ... & Geography - Global Trends & Forecast to ... lyophilization market on the basis of various types, ... the market size of each of these segments ...
(Date:9/19/2014)... Technologies Corp. (NASDAQ: BSTC ), a biopharmaceutical company ... in the U.S. and XIAPEX ® in the ... will present a corporate overview at the 21 st ... The presentation will take place on Friday, September 26, ... in New York, NY . A live ...
(Date:9/19/2014)... VIENNA , Sept. 19, 2014 ... positive interim clinical data for its lead candidate ITCA ... diabetes patients with high baseline HbA1c levels at the ... for the Study of Diabetes (EASD). Data from the ... reduced levels of blood sugar in patients with poorly ...
Breaking Medicine Technology:Lyophilization Market Worth $5,121.5 Million by 2019 2Lyophilization Market Worth $5,121.5 Million by 2019 3BioSpecifics Technologies Corp. to Present at the 21st Annual BioCentury NewsMakers in the Biotech Industry Conference 2Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 2Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 3Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 4
... General Dynamics Information Technology, a business unit of General ... a contract to support the U.S. Army Medical Department,s ... facilities and transition to newly constructed facilities. The indefinite ... by the U.S. Army Corps of Engineers, has a ...
... Oct. 12 Misonix, Inc. (Nasdaq: MSON ... medical device technology, which worldwide is used for acute ... its non-exclusive distribution arrangement in the United States with ... As a result, Misonix will assume exclusive ...
Cached Medicine Technology:General Dynamics Awarded Contract to Outfit and Transition U.S. Army Medical Facilities 2General Dynamics Awarded Contract to Outfit and Transition U.S. Army Medical Facilities 3Misonix Announces Change in Distribution of SonaStar® Surgical Aspiration System in the U.S. 2
The Wire Cutters are designed to cut Kirschner wires up to 2.5 mm diameter easily and smoothly. They are particularly useful for external fixation applications. The Wire Cutters shear fixation wires ...
The osteotome shafts are manufactured with stainless steel and are available both straight and curved in 1/4" and 1/2" sizes....
... Pulse CDC Compact Cardiac Digital Camera is a ... open, patient-friendly gantry, and provides full sized fields ... into your clinic you need a flexible system ... Find out how the Pulse reduces the ...
... is the ultimate objective of neurovascular treatment ... Detachable Coils, occlusion is only the beginning... ... intended for embolization of those intracranial aneurysms ... location, or the patient's general medical condition ...
Medicine Products: