Navigation Links
Cigarette Smoke Fuels Mucus Production in People With Bronchitis

WEDNESDAY, Feb. 23 (HealthDay News) -- Smoking increases the production of mucus associated with chronic bronchitis, a new study shows.

U.S. researchers conducted tests on human airway tissue and on laboratory mice, and found that cigarette smoke suppresses a protein that causes the natural death of mucus-producing cells in the airways of bronchitis patients.

The study appears online ahead of print in the American Journal of Respiratory and Critical Care Medicine.

"Although it is known that chronic mucus secretion is a hallmark of chronic bronchitis, the mechanisms underlying this condition are largely unknown. This study shows that the airway cells that secrete mucus are sustained by cigarette smoke, which suppresses a cell death-inducing protein called Bik," study author Yohannes Tesfaigzi, director of the COPD Program at Lovelace Respiratory Research Institute in Albuquerque, N.M., said in a journal news release.

"Our previous studies show that following inflammatory responses, up to 30 percent of cells lining the airways undergo death and return to the original cell numbers," he continued. "This cell death is aided in part by proteins, including Bik. Disruption of this recovery process may lead to persistent elevation of mucus cell numbers and contribute to airway obstruction found in chronic lung diseases such as chronic bronchitis."

The researchers also found that restoring Bik levels in the airways of cigarette smoke-exposed mice reduced the number of mucus-producing cells.

"These studies lay the foundation to investigate therapies that may restore expression of Bik and reduce the numbers of mucus-producing cells," Tesfaigzi said. "This method may reduce excess secretion of mucus and the airway blockages in patients with chronic bronchitis."

More information

The American Lung Association has more about chronic bronchitis.

-- Robert Preidt

SOURCE: American Journal of Respiratory and Critical Care Medicine, news release, Feb. 17, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Report: $1 Cigarette Tax Increase Would Raise $418.8 Million for Texas and Cut Youth Smoking
2. New Report: $1 Cigarette Tax Increase Would Raise $18.6 Million for Montana and Cut Youth Smoking
3. New Report: $1 Cigarette Tax Increase Would Raise $24.8 Million for Wyoming and Cut Youth Smoking
4. New Report: $1 Cigarette Tax Increase Would Raise $43.3 Million for Utah and Cut Youth Smoking
5. New Report: $1 Cigarette Tax Increase Would Raise $113.9 Million for Colorado and Cut Youth Smoking
6. New Report: $1 Cigarette Tax Increase Would Raise $65.3 Million for Iowa and Cut Youth Smoking
7. Cigars, Pipes No Healthy Alternative to Cigarettes
8. E-Cigarette Maker Green Smoke Tells FDA to Back Off!
9. New Mexico Cigarette Tax Increase Delivers Victory for Kids and Taxpayers, But Increase Needs to Be Permanent
10. Utah Cigarette Tax Increase Delivers Victory for Kids and Taxpayers
11. The Electronic Cigarette Company Challenges the Rt Hon Andy Burnham MP to Ban All Tobacco Products on 21st June 2010
Post Your Comments:
Related Image:
Cigarette Smoke Fuels Mucus Production in People With Bronchitis
(Date:10/13/2017)... ... 2017 , ... “America On The Brink”: the Christian history of the United ... the creation of published author, William Nowers. Captain Nowers and his wife, Millie, ... spent thirty years in the Navy. Following his career as a naval aviator ...
(Date:10/12/2017)... ... 2017 , ... Planet Fitness, one of the largest and fastest growing franchisors ... a flagship location in Covington, LA at 401 N. U.S. Highway 190, in January ... Office Depot in the Holiday Square shopping center. Its location allows it to serve ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical ... Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. ... honor of Morris F. Collen, a pioneer in the field of medical informatics, this ...
(Date:10/12/2017)... ... 2017 , ... Dr. Parsa Mohebi, the Los Angeles based ... the newly revamped Cosmetic Town journal section, featuring articles written by ... as Follicular Unit Extraction (FUE). , Dr. Mohebi says “I enjoy ...
(Date:10/12/2017)... ... 2017 , ... On Saturday, October 21, the Health & Wellness Center at ... raise money for the American Heart Association Heart Walk. Teams of up to 10 ... to keep their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2017 Halo Labs announces the European launch of their ... HORIZON at MIBio 2017 in Cambridge, U.K ... matter in biopharmaceutical samples with unprecedented speed and sensitivity while using ... Backgrounded Membrane Imaging. ... subvisible particle analysis system ...
(Date:9/27/2017)... Israel and NEW YORK , Sept. 27, ... with mobile health and big data solutions, today announced that its MyDario ... Please check your local TV listings for when The Dr. Oz Show ... ... season this month. ...
(Date:9/22/2017)... SAN DIEGO , Sept. 22, 2017 ... ll medical device is now successfully helping those with ... Union. Fibromyalgia diagnosed Amanda in ... getting dressed and washing my hair, experiencing no sleep ... body in painful spasm… I cannot recommend [the AVACEN ...
Breaking Medicine Technology: