Navigation Links
Chronic sinusitis patients experience improved quality of life after endoscopic sinus surgery
Date:12/31/2009

Alexandria, VA Upwards of 76 percent of patients with chronic rhinosinusitis (CRS) experienced significant quality of life (QOL) improvements after undergoing endoscopic sinus surgery (ESS), according to new research in the January 2010 issue of Otolaryngology Head and Neck Surgery.

CRS is a debilitating form of sinusitis that can lead to significant physical symptoms as well as substantial functional and emotional impairment. Symptoms of CRS include stuffy nose, sinus pain and pressure, headache, and sneezing, and CRS is often confused with the cold, flu, or allergies. According to the National Health Interview Survey, CRS affects 14-16 percent of the U.S. population and has significant socioeconomic implications, with annual direct costs of $4.3 billion. Also, patients with sinusitis score lower in QOL measures of bodily pain and social functioning than patients with congestive heart failure, angina, chronic obstructive pulmonary disease, or back pain. Due to the chronic nature of the disease, and the relatively poor response of some patients to initial medical therapies, patients with CRS undergo 500,000 surgical procedures annually, with the primary goal of improving QOL.

The prospective, multi-institutional cohort study analyzed a total 302 patients with CRS from three medical centers between July 2004 and December 2008 and followed the patients for approximately one and a half years postoperatively. The goal of the study was to report outcomes of ESS using prospective, multi-institutional data from a large cohort and validated disease-specific and general health-related QOL instruments. In addition, preoperative patient factors were evaluated for their ability to predict clinically significant outcomes so that surgeons can appropriately counsel patients and optimize surgical case selection.

Results of the study showed 72 -76 percent of patients with CRS and poor baseline QOL experienced clinically significant improvement in disease-specific QOL outcomes after ESS. Clinical factors, including asthma, aspirin intolerance, and prior sinus surgery, as well as preoperative diagnostic testing were found to be important potential predictors of outcomes. However, few of these variables were significant predictors of improvement when multiple risk factors were accounted for in the predictive model. Ultimately, primary ESS patients were twice as likely to improve after surgery as patients undergoing revision ESS, although a baseline measure of disease severity (endoscopy score) was worse in the revision ESS group.

The authors note that although several previous studies have reported improvement in the large majority of patients undergoing ESS, these have been limited by retrospective data collection or unvalidated outcomes. Also, some prospective studies have reported improvement in mean QOL and symptom scores following ESS, but they did not define the proportion of patients that improved. They were largely single institution results, or had limited sample sizes for analysis.

Developed in the 1950s, ESS involves the insertion of the endoscope, a thin fiber-optic tube, into the nose for a direct visual examination of the openings into the sinuses. With state of the art micro-telescopes and instruments, abnormal and obstructive tissues are then removed. Some advantages of the procedure are that the surgery is less extensive, there is often less removal of normal tissues, and it can frequently be performed on an outpatient basis.


'/>"/>

Contact: Jessica Mikulski
newsroom@entnet.org
703-535-3762
American Academy of Otolaryngology -- Head and Neck Surgery
Source:Eurekalert

Related medicine news :

1. New research shows how chronic stress worsens neurodegenerative disease course
2. Katie Lee Joel to Conduct Cooking Demonstration for Local Patients With Chronic Kidney Disease
3. Study identifies key player in the bodys immune response to chronic stress
4. Preparation for Natural Disasters Critical for People With Diabetes, Chronic Medical Conditions
5. Patient Advocate Foundation Launches Program to Help Uninsured Virginians with Chronic, Debilitating and Life-Threatening Illness Access Quality Healthcare
6. The Leukemia & Lymphoma Society Hosts Workshop On Weighing Treatment Options For Chronic Myelogenous Leukemia
7. Link Between Chronic Pain and Insomnia Uncovered at PAINWeek 2007
8. Methadone and systematic follow-up: the best solution for managing chronic pain
9. NASN Joins Partnership to Fight Chronic Disease
10. Stomach Virus a Culprit in Chronic Fatigue Syndrome
11. Chronic fatigue syndrome linked to stomach virus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/21/2017)... ... ... the largest manufacturer of oats in China, is now aiming at global business expansion, ... globally as one of the healthiest cereals, XieQingkui, the founder of Seamild, strongly recommends ... sow the seed of good karma. Buddhism spirit featuring benevolence and sacrifice are the ...
(Date:1/21/2017)... ... 21, 2017 , ... Pacifica Graduate Institute’s Alumni Association announced ... events for its annual meeting “Coming Home 2017,” an activity-packed weekend of educational ... will be held on Friday January 27 through Sunday, January 29, 2017 at ...
(Date:1/21/2017)... ... 21, 2017 , ... Santa Rosa Orthopaedics (SRO) is excited ... 167 Lynch Creek Way. The Petaluma office features three comfortable patient exam rooms, ... services and on-site x-ray services. Two multi-specialist orthopaedic surgeons Dr. Neema Pourtaheri ...
(Date:1/21/2017)... ... 21, 2017 , ... The Nobel Biocare™ dental implant company ... for its creos™ line of bone regenerative products. Specifically, the Nobel ... utilizes creos™ allo.gain™ bone graft for a variety of bone reconstruction procedures. In ...
(Date:1/20/2017)... ... 2017 , ... A new partnership between Goodwill® and Roadie, Inc. aims to ... from clothes to couches to dressers and bicycles. Roadie — the national on-the-way delivery ... Goodwill donation center through February 28th. , “January is an exciting time when ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... 2017 ARMO BioSciences, Inc., a late-stage immuno-oncology ... Company,s lead investigational immuno-oncology drug AM0010 (PEGylated Interleukin-10) at ... Society of Clinical Oncology (ASCO), taking place January 19-21, ... "AM0010 induces the expansion of novel ... cells in the blood and tumors of our patients," ...
(Date:1/20/2017)... Jan 20, 2017 Research and Markets ... Market (by Devices, Implant Types, OTC Amplifiers, Diagnostic Instruments), Sales ... their offering. ... Global Hearing Aids Market Sales Volume, Company Analysis and ... high-growth hearing aid industry. The growing prevalence of ...
(Date:1/20/2017)... PARK, Fla. , Jan. 20, 2017 Wells ... located at 3796 Howell Branch Rd in Winter ... Winter Park . Operations have been consolidated ... Specialty Pharmacy is also pleased to announce that Chad ... to President of the Company effective immediately. Mr. Tomlinson is ...
Breaking Medicine Technology: