Navigation Links
Chronic Pain Harms Brain's Wiring
Date:2/8/2008

Constant firing of neurons could cause permanent damage, researchers say

FRIDAY, Feb. 8 (HealthDay News) -- Chronic pain can disrupt brain function and cause problems such as disturbed sleep, depression, anxiety and difficulty making simple decisions, a U.S. study finds.

Researchers at Northwestern University's Feinberg School of Medicine in Chicago used functional MRI to scan brain activity in people with chronic low back pain while they tracked a moving bar on a computer screen. They did the same thing with a control group of people with no pain.

In those with no pain, the brain regions displayed a state of equilibrium. When one region was active, the other regions calmed down. But in people with chronic pain, the front region of the cortex mostly associated with emotion "never shuts up," study author Dante Chialvo, an associate research professor of physiology, said in a prepared statement.

This region remains highly active, which wears out neurons and alters their connections to each other. This constant firing of neurons could cause permanent damage.

"We know when neurons fire too much they may change their connections with other neurons or even die, because they can't sustain high activity for so long," Chialvo said.

"If you are a chronic pain patient, you have pain 24 hours a day, seven days a week, every minute of your life. That permanent perception of pain in your brain makes these areas in your brain continuously active. This continuous dysfunction in the equilibrium of the brain can change the wiring forever and could hurt the brain," Chialvo explained.

These changes "may make it harder for you to make a decision or be in a good mood to get up in the morning. It could be that pain produces depression and the other reported abnormalities, because it disturbs the balance of the brain as a whole," he said.

The study was published in the Feb. 6 issue of The Journal of Neuroscience.

Chialvo said the findings show that, along with finding new ways to treat pain, it's also important to develop methods to evaluate and prevent disruption of brain function caused by chronic pain.

More information

The American Academy of Family Physicians has more about chronic pain.



-- Robert Preidt



SOURCE: Northwestern University, news release, Feb. 5, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New research shows how chronic stress worsens neurodegenerative disease course
2. Katie Lee Joel to Conduct Cooking Demonstration for Local Patients With Chronic Kidney Disease
3. Study identifies key player in the bodys immune response to chronic stress
4. Preparation for Natural Disasters Critical for People With Diabetes, Chronic Medical Conditions
5. Patient Advocate Foundation Launches Program to Help Uninsured Virginians with Chronic, Debilitating and Life-Threatening Illness Access Quality Healthcare
6. The Leukemia & Lymphoma Society Hosts Workshop On Weighing Treatment Options For Chronic Myelogenous Leukemia
7. Link Between Chronic Pain and Insomnia Uncovered at PAINWeek 2007
8. Methadone and systematic follow-up: the best solution for managing chronic pain
9. NASN Joins Partnership to Fight Chronic Disease
10. Stomach Virus a Culprit in Chronic Fatigue Syndrome
11. Chronic fatigue syndrome linked to stomach virus
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chronic Pain Harms Brain's Wiring
(Date:5/26/2017)... , ... May 26, 2017 , ... Yisrayl Hawkins, Pastor ... publication this week that is focusing on the Peace Agreements being discussed by President ... East sprint in a race to try to speed up peace talks in the ...
(Date:5/26/2017)... ... ... Lowe acts as host and helps educate and inform the public using the “Informed” ... reconnect with America as it explores some of the best places to hike and ... inventive new place for a family vacation, and have discovered hiking. Many will agree ...
(Date:5/26/2017)... ... May 26, 2017 , ... “When the Stars Lead Home”: ... the creation of published author Laura Weigel Douglas, an avid reader who lives in ... house that sometimes feels like Green Hills Adventure Camp. She couldn’t be more grateful. ...
(Date:5/26/2017)... ... May 26, 2017 , ... ... recipient of proceeds from its 14th Annual Clays for Kids fundraiser, to be ... 30, Bennett, Colorado. , As part of BluSky’s partnership with The Adoption ...
(Date:5/26/2017)... ... ... “Cactus Jack: Against All Odds”: the story of Coach Cactus Jack and the impact ... the creation of published author, Walter Hubbard, a retired wildlife and fisheries biologist and ... Walter. Walter and Jane have three adult children and a granddaughter. Walter ...
Breaking Medicine News(10 mins):
(Date:5/23/2017)... May 23, 2017  Leaf Healthcare, recognized for ... devices for pressure ulcer prevention, will unveil its ... of Critical Care Nurses, National Teaching Institute and ... The Leaf Patient Monitoring System is the ... hospital environment.  The system seamlessly tracks patient movement ...
(Date:5/22/2017)... , May 22, 2017  As the specialty ... whole continue to make the revolutionary shift from ... important for ensuring positive patient outcomes and shaping ... are shifting focus away from clinical trials and ... of long-term specialty drug therapy utilization in precise ...
(Date:5/18/2017)... , May 17, 2017  Bayer announced today that ... will be presented at the 53 rd Annual ... taking place June 2-6 in Chicago ... ASCO span prostate, colorectal, liver and thyroid cancers, as ... the Phase II CHRONOS-1 trial of copanlisib in patients ...
Breaking Medicine Technology: