Navigation Links
Chronic Exposure to Solvents Disturbs Brain's Wiring
Date:4/18/2008

Changes in dopamine receptor density affects memory and psychomotor speed, study says

FRIDAY, April 18 (HealthDay News) -- Long-term exposure to solvents in products such as paints and dry cleaning agents may cause disturbances in the brain's wiring, researchers report.

These abnormalities play a role in a condition called chronic solvent-induced encephalopathy (CSE), the Dutch team conclude in the April issue of the Annals of Neurology.

People with CSE experience problems with memory, attention and psychomotor function long after exposure to solvents has ceased, according to background information in the study. Cases of CSE, a recognized occupational health problem, are increasing in a number of western nations.

This study found that disturbances within the brain's frontal-striatal-thalamic (FST) circuitry are related to the clinical characteristics of CSE, as well as to the severity of exposure to solvents.

The study included 10 CSE patients who'd been exposed to solvents and had mild to severe cognitive impairment, 10 people who'd been exposed to solvents but had no CSE symptoms, and 11 people with no exposure to solvents and no CSE symptoms.

All the participants underwent a number of tests, including MRI and single photon emission computed tomography (SPECT) scans to assess their FST circuitry.

The CSE patients had reduced striatal dopamine D2 receptor (D2R) binding ratios, which were predictive of impaired psychomotor speed and attention, and were also linked to solvent exposure severity, the study authors found. Dopamine receptor density is believed to play a role in psychomotor speed.

The 10 people who were exposed to solvents but had no CSE symptoms showed similar reductions but to a lesser extent. Both groups showed reduced levels of choline (which plays a role in neurotransmission) in the frontal grey matter of the brain.

The results indicate that
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Overuse of Opioids, Barbiturates Boosts Chronic Migraine Risk
2. New Jersey Leaders Join Forces to Battle Chronic Disease
3. Disturbances in brain circuitry linked to chronic exposure to solvents
4. Potential blood test for chronic sinusitis identified
5. Studies Confirm Balloon Sinuplasty(TM) Helps Chronic Sinusitis Patients
6. Disease Management Programs that Focus on Needs of Chronically Ill Patients Can Provide Positive, Cost-Effective Results
7. Chronically Ill Patients Get More Care, Less Quality, Says Latest Dartmouth Atlas
8. Cato Research Ltd. and Advanced Targeting Systems, Inc. Partner to Develop SP-SAP for Chronic Pain
9. Adolescents with chronic insomnia report twofold to fivefold increase in personal problems
10. Annual Economic Impact of Chronic Disease on Ohio Economy is $56.8 Billion
11. Data study suggests cortisol could alleviate for chronic fatigue syndrome and fibromyalgia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2014)... Cardiomyopathy (heart muscle disease) is ... myocardium (the heart muscle) for any reason, usually ... (breathlessness) and peripheral edema (swelling of the legs). ... dangerous forms of irregular heart beat and sudden ... is dilated cardiomyopathy. , Clinical trial report, “Cardiomyopathy ...
(Date:8/23/2014)... New York (PRWEB) August 23, 2014 ... from the 2012 GranuFlo and NaturaLyte dialysis concentrate ... litigation underway in U.S. District Court, District of ... updated docket report issued by the U.S. Judicial ... at least 2,028 claims are pending in the ...
(Date:8/23/2014)... "When men sit down to use the toilet, ... water inside the bowl, the interior rim of the ... inventors from Naugatuck, and Bridgeport, Conn. "In order to ... , They developed the IPSAFE to prevent the penis ... and seat. This minimizes exposure to germs, which helps ...
(Date:8/23/2014)... New York, NY (PRWEB) August 23, 2014 ... Times (NYT) reported on a data breach suffered ... nationwide, that saw the compromise of 4.5 million records ... and social security numbers. According to Mandiant, who was ... attack emanated from an advanced group of cyber ...
(Date:8/23/2014)... 2014 Pixel Film Studios, a leader of ... release of ProIntro Vol.3, a customizable title tool for ... tile just by dragging ProIntro Vol.3 in their timeline" says ... a definite time saver and i think our users will ... beautifully designed titles made with Final Cut Pro X users ...
Breaking Medicine News(10 mins):Health News:Cardiomyopathy (Heart Muscle Disease) Therapeutics Clinical Trials Market 2014 Analysis in a New Report Available at MarketOptimizer.org 2Health News:Cardiomyopathy (Heart Muscle Disease) Therapeutics Clinical Trials Market 2014 Analysis in a New Report Available at MarketOptimizer.org 3Health News:Cardiomyopathy (Heart Muscle Disease) Therapeutics Clinical Trials Market 2014 Analysis in a New Report Available at MarketOptimizer.org 4Health News:GranuFlo Lawsuits Mount in Federal Litigation, as Filings Surpass 2,000, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Mount in Federal Litigation, as Filings Surpass 2,000, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Mount in Federal Litigation, as Filings Surpass 2,000, Bernstein Liebhard LLP Reports 4Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 2Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 3Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 4Health News:A new plugin was announced today, ProIntro Vol.3 from Pixel Film Studios for Final Cut Pro X 2
... New advisory puts worries about possible link to heart disease ... that discussion about the omega-6 fatty acids found in vegetable ... is unfounded, a new science advisory from the American Heart ... in the nutrition world that omega-6 fatty acids might be ...
... Jan. 26 Cooperative of American Physicians, Inc. Chief ... 2009 recipient of the Spirit of Life(R) ... gala black tie dinner celebrating Mr. Weidner and his ... in Pasadena, California on Saturday, November 14. Spirit of ...
... Exclusive Retail Partner WARREN, N.J., Jan. 26 ... announced today that it is joining the fight ... LG Pink Flare limited edition handset, available exclusively ... http://www.newscom.com/cgi-bin/prnh/20090126/NY62794 ) , (Logo: http://www.newscom.com/cgi-bin/prnh/20070613/VIRGINMOBILE ...
... EDGE, N.J., Jan. 26 Nephros, Inc. (Pink Sheets: ... products for therapeutic applications, infection control, and water purification, ... in the Pink Sheets under the symbol "NEPH." ... been suspended from trading on the NYSE Alternext US ...
... overestimate the dangers, study finds, , , MONDAY, Jan. 26 ... U.S. minorities and the disabled more so than on ... as well as the disabled and mentally ill, are ... terrorism fears, such as avoiding certain activities. These ...
... Airlines to Fly 14 Teenage Amputees for a Week-Long ... Airlines and Texas Scottish Rite Hospital for Children have ... on an all-expense-paid ski trip to Winter Park, Colo., ... departs from Dallas/Fort Worth International Airport (DFW) today and ...
Cached Medicine News:Health News:Omega-6 Fatty Acids Can Be Good for You 2Health News:Omega-6 Fatty Acids Can Be Good for You 3Health News:James L. Weidner Named 2009 Spirit of Life(R) Award Recipient by City of Hope 2Health News:Virgin Mobile USA Launches Limited Edition Pink Flare Handset to Benefit Susan G. Komen for the Cure(R) 2Health News:Virgin Mobile USA Launches Limited Edition Pink Flare Handset to Benefit Susan G. Komen for the Cure(R) 3Health News:Nephros Common Stock Now Quoted in Pink Sheets 2Health News:Nephros Common Stock Now Quoted in Pink Sheets 3Health News:Terror Fears Tougher on Minorities, Disabled 2Health News:Terror Fears Tougher on Minorities, Disabled 3Health News:American Airlines and Texas Scottish Rite Hospital for Children Host Annual Amputee Ski Trip 2Health News:American Airlines and Texas Scottish Rite Hospital for Children Host Annual Amputee Ski Trip 3
(Date:8/22/2014)... Aug. 22, 2014 MC Medical, a subsidiary of ... Columbus, OH medical device company, have ... laparoscopic and robotic visualization system in Japan ... sale in Japan in the latter ... and an extensive product portfolio in endoscopic surgery market in ...
(Date:8/22/2014)... , Aug. 22, 2014   Zacks Equity Research highlights ... of the Day and Panera (Nasdaq: PNRA - Free Report ... Research provides analysis on Amicus Therapeutics (Nasdaq: FOLD - Free ... Shire (Nasdaq: SHPG - Free Report ). Here ... Bull of the Day : The biotech bull ...
(Date:8/22/2014)... LA JOLLA , Cali ., Aug. ... Annual International Papillomavirus Conference shows that a therapy being developed ... including the two that cause 70 percent of all cervical ... models, HTI-1968 blocked the replication of HPV-16, HPV-18 and HPV-11 ... Thomas Broker , Ph.D., who presented the findings at ...
Breaking Medicine Technology:MC Medical agrees to be the exclusive distributor of FloShield products in Japan 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 3Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 4Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 5Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 6Study shows Hera Therapeutics experimental compound shuts down human papillomavirus that causes most cervical cancer 2
... Frankfurt am Main Emergency Medical Services (EMS) ... MASI ), the inventor of rainbow® Pulse CO-Oximetry™, rainbow ... Perfusion pulse oximetry, today jointly announced that every EMS ... equipped with a Masimo Rad-57® Pulse CO-Oximeter—making carbon monoxide ...
... Aug. 26 Cardioxyl Pharmaceuticals, Inc. , a ... of cardiovascular disease, today announced that it has initiated ... candidate, CXL-1020, for the treatment of patients with acute ... for patients at the time of discharge from U.S. ...
Cached Medicine Technology:Frankfurt am Main Emergency Medical Services Makes Masimo Rad-57 Pulse CO-Oximeters Mandatory for All Vehicles 2Frankfurt am Main Emergency Medical Services Makes Masimo Rad-57 Pulse CO-Oximeters Mandatory for All Vehicles 3Frankfurt am Main Emergency Medical Services Makes Masimo Rad-57 Pulse CO-Oximeters Mandatory for All Vehicles 4Frankfurt am Main Emergency Medical Services Makes Masimo Rad-57 Pulse CO-Oximeters Mandatory for All Vehicles 5Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 2Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 3Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 4
Katena ophthalmic burr for polishing pterygiums, includes one round diamond burr and has an storage case....
Illuminated Trial Lens Set is an attractive set of trial lenses worked to a high standard of accuracy....
Trial Lens Sets....
... is the first ... to offer two kinds ... and taurine. Cleans, rinses, ... and conditions any soft ...
Medicine Products: