Navigation Links
Chronic 'Butter Flavoring' Exposure Linked to Harmful Brain Process
Date:8/6/2012

MONDAY, Aug. 6 (HealthDay News) -- Chronic exposure to an artificial butter flavoring ingredient, known as diacetyl, may worsen the harmful effects of a protein in the brain linked to Alzheimer's disease, according to a new study.

The findings should serve as a red flag for factory workers with significant exposure to the food-flavoring ingredient, researchers from the University of Minnesota said in the report published in a recent issue of the journal Chemical Research in Toxicology.

Diacetyl is used to give a buttery taste and aroma to common food items such as margarines, snack foods, candy, baked goods, pet foods and other products.

The investigators pointed out that previous studies have already linked diacetyl to respiratory and other health problems among workers at microwave popcorn and food-flavoring plants.

Although diacetyl forms naturally in fermented beverages, such as beer and wine, its chemical structure is similar to a substance that makes beta-amyloid proteins clump together in the brain. This clumping, the study authors noted, is a hallmark of Alzheimer's disease.

In their study, the researchers found that diacetyl also increases the amount of beta-amyloid clumping in the brain. And it worsened the beta-amyloid protein's harmful effects on nerve cells grown in a lab when the cells were exposed to the same levels of diacetyl that factory workers might be exposed to in their jobs.

The study authors pointed out that other experiments revealed that diacetyl also crosses the "blood-brain barrier," which helps protect the brain from dangerous substances. Diacetyl also prevented a beneficial protein from protecting nerve cells.

"In light of the chronic exposure of industry workers to diacetyl, this study raises the troubling possibility of long-term neurological toxicity mediated by diacetyl," Robert Vince and colleagues concluded in a news release from the American Chemical Society.

The study was funded by the Center for Drug Design research endowment funds at the University of Minnesota.

While the study found an association between chronic diacetyl exposure and certain brain protein processes, it did not prove a cause-and-effect relationship.

More information

The U.S. National Library of Medicine has more about Alzheimer's disease.

-- Mary Elizabeth Dallas

SOURCE: American Chemical Society, news release, Aug. 1, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Common Skin Cancer a Chronic Condition, Study Says
2. Chronic vulvar pain related to irritable bowel syndrome, fibromyalgia and interstitial cystitis
3. Study finds people have difficulty controlling multiple chronic conditions
4. More Americans Have at Least 2 Chronic Health Issues: CDC
5. Asthma is the most common chronic disease among Olympic athletes
6. A nursing program shows promise for reducing deaths from chronic illnesses
7. U-M researchers identify new genetic cause for chronic kidney disease
8. Childhood adversity increases risk for depression and chronic inflammation
9. Chronic Pain May Depend on Emotional Reaction to Injury
10. Analysis of KRYSTEXXA phase III data demonstrates improved health-related quality of life and physical function in refractory chronic gout patients
11. Recent Report Reveals Dramatic Increase in Chronic Disease in Pets
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chronic 'Butter Flavoring' Exposure Linked to Harmful Brain Process
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June ... -based mobile pulmonary function testing company, is now able to ... devices developed by ndd Medical Technologies , Inc. ... done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ... , can get any needed testing done in the comfort of ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
(Date:6/24/2016)... NAMUR , Belgium , ...  (NYSE MKT: VNRX), today announced the appointment of ... Board of Directors as a Non-Executive Director, effective ... the Company,s Audit, Compensation and Nominations and Governance ... Board, Dr. Futcher will provide independent expertise and ...
Breaking Medicine Technology: