Navigation Links
Chronic 'Butter Flavoring' Exposure Linked to Harmful Brain Process
Date:8/6/2012

MONDAY, Aug. 6 (HealthDay News) -- Chronic exposure to an artificial butter flavoring ingredient, known as diacetyl, may worsen the harmful effects of a protein in the brain linked to Alzheimer's disease, according to a new study.

The findings should serve as a red flag for factory workers with significant exposure to the food-flavoring ingredient, researchers from the University of Minnesota said in the report published in a recent issue of the journal Chemical Research in Toxicology.

Diacetyl is used to give a buttery taste and aroma to common food items such as margarines, snack foods, candy, baked goods, pet foods and other products.

The investigators pointed out that previous studies have already linked diacetyl to respiratory and other health problems among workers at microwave popcorn and food-flavoring plants.

Although diacetyl forms naturally in fermented beverages, such as beer and wine, its chemical structure is similar to a substance that makes beta-amyloid proteins clump together in the brain. This clumping, the study authors noted, is a hallmark of Alzheimer's disease.

In their study, the researchers found that diacetyl also increases the amount of beta-amyloid clumping in the brain. And it worsened the beta-amyloid protein's harmful effects on nerve cells grown in a lab when the cells were exposed to the same levels of diacetyl that factory workers might be exposed to in their jobs.

The study authors pointed out that other experiments revealed that diacetyl also crosses the "blood-brain barrier," which helps protect the brain from dangerous substances. Diacetyl also prevented a beneficial protein from protecting nerve cells.

"In light of the chronic exposure of industry workers to diacetyl, this study raises the troubling possibility of long-term neurological toxicity mediated by diacetyl," Robert Vince and colleagues concluded in a news release from the American Chemical Society.

The study was funded by the Center for Drug Design research endowment funds at the University of Minnesota.

While the study found an association between chronic diacetyl exposure and certain brain protein processes, it did not prove a cause-and-effect relationship.

More information

The U.S. National Library of Medicine has more about Alzheimer's disease.

-- Mary Elizabeth Dallas

SOURCE: American Chemical Society, news release, Aug. 1, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Common Skin Cancer a Chronic Condition, Study Says
2. Chronic vulvar pain related to irritable bowel syndrome, fibromyalgia and interstitial cystitis
3. Study finds people have difficulty controlling multiple chronic conditions
4. More Americans Have at Least 2 Chronic Health Issues: CDC
5. Asthma is the most common chronic disease among Olympic athletes
6. A nursing program shows promise for reducing deaths from chronic illnesses
7. U-M researchers identify new genetic cause for chronic kidney disease
8. Childhood adversity increases risk for depression and chronic inflammation
9. Chronic Pain May Depend on Emotional Reaction to Injury
10. Analysis of KRYSTEXXA phase III data demonstrates improved health-related quality of life and physical function in refractory chronic gout patients
11. Recent Report Reveals Dramatic Increase in Chronic Disease in Pets
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chronic 'Butter Flavoring' Exposure Linked to Harmful Brain Process
(Date:6/27/2017)... ... June 27, 2017 , ... PR ... an upcoming case studies guidebook. This guidebook offers an excellent branding and exposure ... include articles, case studies and how-to’s that fall into the following categories:, ...
(Date:6/27/2017)... ... , ... Dr. Richard Amato, a respected periodontist in Monroe, CT, ... Implant Center of Connecticut. As part of the renovation, the cutting-edge practice added two ... to improve patient comfort while making it possible for Dr. Amato to provide even ...
(Date:6/27/2017)... North Hollywood, CA (PRWEB) , ... June 27, ... ... on orthodontic treatments . Orthodontics is a dental specialty that focuses on ... other appliances. Benefits include improved aesthetics and function. , North Hollywood ...
(Date:6/26/2017)... ... June 26, 2017 , ... Torrance dentist, Dr. Robert ... be one of the most noticeable aspects of a person’s appearance. A healthy, radiant ... is born with beautiful, balanced teeth, everyone can have the smile of their dreams ...
(Date:6/26/2017)... ... June 26, 2017 , ... The Centers for Advanced ... hiring of Richard Robinson as chief operating officer (COO). In this role, Robinson ... proven track record of simplifying business processes and developing growth strategies to increase ...
Breaking Medicine News(10 mins):
(Date:6/20/2017)... HILLS, Calif. , June 20, 2017 SkylineDx ... the use of MMprofiler with SKY92, the company,s prognostic ... In a poster presentation at the 22 nd ... Madrid, Spain , SkylineDx researchers will demonstrate ... patients. In a separate e-poster presentation ...
(Date:6/14/2017)... HAMPTON, Va. , June 14, 2017  ivWatch ... safety and effectiveness of intravenous (IV) therapy, is pleased ... in the category of Nonsurgical Hospital Supplies and Equipment ... premier awards program for the medtech industry. The award ... at the Jacob K. Javits Center in ...
(Date:6/11/2017)... June 10, 2017  Eli Lilly and Company (NYSE: ... Phase 3 studies of galcanezumab, an investigational treatment for ... data on several key secondary endpoints for galcanezumab compared ... these studies (EVOLVE-1, EVOLVE-2 and REGAIN) will be presented ... meeting in Boston . ...
Breaking Medicine Technology: