Navigation Links
Chronic 'Butter Flavoring' Exposure Linked to Harmful Brain Process

MONDAY, Aug. 6 (HealthDay News) -- Chronic exposure to an artificial butter flavoring ingredient, known as diacetyl, may worsen the harmful effects of a protein in the brain linked to Alzheimer's disease, according to a new study.

The findings should serve as a red flag for factory workers with significant exposure to the food-flavoring ingredient, researchers from the University of Minnesota said in the report published in a recent issue of the journal Chemical Research in Toxicology.

Diacetyl is used to give a buttery taste and aroma to common food items such as margarines, snack foods, candy, baked goods, pet foods and other products.

The investigators pointed out that previous studies have already linked diacetyl to respiratory and other health problems among workers at microwave popcorn and food-flavoring plants.

Although diacetyl forms naturally in fermented beverages, such as beer and wine, its chemical structure is similar to a substance that makes beta-amyloid proteins clump together in the brain. This clumping, the study authors noted, is a hallmark of Alzheimer's disease.

In their study, the researchers found that diacetyl also increases the amount of beta-amyloid clumping in the brain. And it worsened the beta-amyloid protein's harmful effects on nerve cells grown in a lab when the cells were exposed to the same levels of diacetyl that factory workers might be exposed to in their jobs.

The study authors pointed out that other experiments revealed that diacetyl also crosses the "blood-brain barrier," which helps protect the brain from dangerous substances. Diacetyl also prevented a beneficial protein from protecting nerve cells.

"In light of the chronic exposure of industry workers to diacetyl, this study raises the troubling possibility of long-term neurological toxicity mediated by diacetyl," Robert Vince and colleagues concluded in a news release from the American Chemical Society.

The study was funded by the Center for Drug Design research endowment funds at the University of Minnesota.

While the study found an association between chronic diacetyl exposure and certain brain protein processes, it did not prove a cause-and-effect relationship.

More information

The U.S. National Library of Medicine has more about Alzheimer's disease.

-- Mary Elizabeth Dallas

SOURCE: American Chemical Society, news release, Aug. 1, 2012

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Common Skin Cancer a Chronic Condition, Study Says
2. Chronic vulvar pain related to irritable bowel syndrome, fibromyalgia and interstitial cystitis
3. Study finds people have difficulty controlling multiple chronic conditions
4. More Americans Have at Least 2 Chronic Health Issues: CDC
5. Asthma is the most common chronic disease among Olympic athletes
6. A nursing program shows promise for reducing deaths from chronic illnesses
7. U-M researchers identify new genetic cause for chronic kidney disease
8. Childhood adversity increases risk for depression and chronic inflammation
9. Chronic Pain May Depend on Emotional Reaction to Injury
10. Analysis of KRYSTEXXA phase III data demonstrates improved health-related quality of life and physical function in refractory chronic gout patients
11. Recent Report Reveals Dramatic Increase in Chronic Disease in Pets
Post Your Comments:
Related Image:
Chronic 'Butter Flavoring' Exposure Linked to Harmful Brain Process
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... , ... People across the U.S. are sharpening their pencils and honing their ... in which patients and their families pay tribute to a genetic counselor by nominating ... of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, ...
(Date:6/24/2016)... York, NY (PRWEB) , ... June 24, 2016 ... ... publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as a ... that “the most beautiful women in the world, and the most handsome men, ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Frederick area economy by obtaining investment capital for emerging technology companies. ... years that have already resulted in more than a million dollars of capital ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
(Date:6/23/2016)... Revolutionary technology includes multi-speaker listening ... industry leaders in advanced audiology and hearing aid technology, ... ™, the world,s first internet connected hearing aid that ...      (Photo: ) , ... ,world firsts,: , TwinLink™ - the first ...
Breaking Medicine Technology: