Navigation Links
Chronic Bowel Disease Drugs Linked to Skin Cancer Risk
Date:11/22/2011

TUESDAY, Nov. 22 (HealthDay News) -- Some patients with inflammatory bowel disease may be at increased risk for skin cancer due to their use of immunosuppressant drugs to treat the intestinal disorder, according to the results of two new studies.

The studies, published in the November issue of the journal Gastroenterology, noted that immunosuppressants are commonly used to treat patients with irritable bowel disease, or IBD. Currently, there are no specific recommendations for skin cancer screening in IBD patients.

In one study, French researchers led by Dr. Laurent Peyrin-Biroulet, of University Hospital of Nancy, found that both past and present use of a widely used class of immunosuppressants called thiopurines significantly increased the risk of non-melanoma skin cancer in irritable bowel disease patients.

"The increased risk of skin cancer that we found in our study was observed in all patients, even before the age of 50 years. As expected, this risk increased with age. All patients with irritable bowel disease currently receiving or having previously received thiopurines should protect their skin from UV radiation and receive regular dermatologic screening, regardless of their age," Peyrin-Biroulet said in a news release from the American Gastroenterological Association.

Non-melanoma skin cancer includes basal cell carcinoma and squamous cell carcinoma, which are the most common cancers diagnosed in North America.

In the second study, Canadian researchers found that certain people with inflammatory bowel disease, such as men with a form of the disorder known as Crohn's disease, may already be at increased risk for basal cell carcinoma, and the use of thiopurines increases this risk.

"All individuals should be protecting themselves against skin cancer," lead author Dr. Harminder Singh, of the University of Manitoba, said in the news release. "But, it is especially important that physicians stress the need to be extra vigilant about skin care with their irritable bowel disease patients, especially among those exposed to immunosuppressants such as thiopurines."

However, Singh and his colleagues added that there was only a small absolute increased risk of non-melanoma skin cancer seen in the study, which may not warrant stopping treatment with thiopurines in IBD patients who need the immunosuppressants to control their disease.

More information

The U.S. National Cancer Institute has more about skin cancer prevention.

-- Robert Preidt

SOURCE: American Gastroenterological Association, news release, Nov. 21, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Profile Drawn of People With Chronic Jaw Pain
2. Loss of weight associated with chronic illness may soon have first treatment
3. FDA funds Rochester researchers to give chronic and acute pain clinical trials a makeover
4. UT MD Anderson study finds acupuncture can prevent radiation-induced chronic dry mouth
5. Low vitamin D levels do not increase the risk of chronic obstructive pulmonary disease
6. Children suffer unnecessarily from chronic postoperative pain
7. Childhood diet lower in fat and higher in fiber may lower risk for chronic disease in adulthood
8. Religious, spiritual support benefits men and women facing chronic illness, MU study finds
9. PATH B, a comprehensive support program in Europe for patients with chronic hepatitis B launched
10. Heart health impacts wellbeing of patients with chronic obstructive pulmonary disease
11. Chronic dialysis for kidney disease patients now started substantially earlier
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chronic Bowel Disease Drugs Linked to Skin Cancer Risk
(Date:2/20/2017)... Houston, TX (PRWEB) , ... February 20, 2017 ... ... he is now offering a full range of emergency dental care at his ... teeth and gums. When patients experience dental emergencies, they are at risk for ...
(Date:2/20/2017)... ... February 20, 2017 , ... Florida Hospital Pepin Heart Institute ... thrombolysis machine, a state-of-the-art device that breaks up life-threatening blood clots by combining ... Foundation. , “We greatly appreciate this gift from Constellation Brands. We are also ...
(Date:2/19/2017)... RI (PRWEB) , ... February 19, 2017 , ... ... is proven to result in better care, and MEDfx and the Delaware Health ... state of Delaware. , As the nation’s first state-wide health information exchange, DHIN ...
(Date:2/18/2017)... ... February 17, 2017 , ... Butler Mobility invited Ken ... Stairlift and other Butler products. Ken was impressed with the safety and reliability ... endorse the product on his show. This endorsement by Ken Matthews can be ...
(Date:2/18/2017)... ... 2017 , ... A new directory from the Senior Veterans ... connect elderly veterans of America's armed forces to a range of senior care ... on this year's increase in the Veterans Pension with Aid & Attendance for ...
Breaking Medicine News(10 mins):
(Date:2/19/2017)... , February 18, 2017 Marapharm ... to purchase a Medical Delivery Service with the specific ... transactions between qualified patients and caregivers. The delivery service ... located in the Coachella Valley, California ... Los Angeles area to the West, population ...
(Date:2/18/2017)... Feb. 17, 2017  Pharmaceutical companies have long used advisory ... in development or already on the market.   ... industry to alter how it manages advisory board meetings. To ... Practices, LLC conducted a new study focused on key aspects ... ...
(Date:2/17/2017)... NEW HAVEN, Conn. , Feb. 17, 2017 /PRNewswire/ ... new class of drugs based on protein degradation, today ... oral androgen receptor (AR) PROTAC during a poster session ... Cancers Symposium (ASCO GU) in Orlando, FL. ... today continue to validate our platform and the potential ...
Breaking Medicine Technology: