Navigation Links
Chromosome Linked to Diabetics' Heart Risks
Date:11/25/2008

Genetic variation identifies those with poor glucose control likely to have artery disease

TUESDAY, Nov. 25 (HealthDay News) -- Adding to earlier research, a new study has identified a genetic variation that increases the risk of coronary artery disease (CAD) in type 2 diabetes patients with poor sugar glucose (glycemic) control.

Previous research has found that genetic variations on a genetic chromosome known as chromosome 9p21 are associated with increased risk of CAD in the general population.

The team at the Joslin Diabetes Center at Harvard Medical School studied more than 1,500 people with type 2 diabetes (including 322 diagnosed with CAD) who were tested for a gene variation of chromosome 9p21 and checked for long-term glycemic control.

The findings were published in the Nov. 26 issue of the Journal of the American Medical Association.

Compared to patients with good glycemic control and no 9p21 gene risk variant, those subjects with two risk gene variants and good glycemic control were twice as likely to have CAD, while those with two risk gene variants and poor glycemic control were four times more likely to have CAD.

This association was strongest when long-term (seven years) glycemic control was measured in patients with two risk gene variants and a history of poor glycemia, and for patients with the same genotype but not long-term poor glycemia. The researchers also noted a similar interaction between the 9p21 variant and poor glycemia was associated with the death rate after 10 years.

"In conclusion, 9p21 (variant) and poor glycemic control interact in determining the odds of CAD in type 2 diabetes," Dr. Alessandro Doria and colleagues are quoted in a medical association news release. "This finding may have implications for our understanding of atherogenesis (the process of plaque forming in arteries) in diabetes and for the design of more effective prevention st
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Grant Supports Study of Abnormal Ring-Shaped Chromosomes
2. Optherion Licenses Worldwide Rights to Develop Age-Related Macular Degeneration Diagnostics Based on Chromosome 10 Genetic Variations
3. Herceptin helps women with multiple chromosomes containing HER2 gene, study finds
4. Chromosome Abnormalities Raise Risk for Autism
5. Missing Chromosome Improves Response to Brain Tumor Treatment
6. Penn researchers identify first sex chromosome gene involved in meiosis and male infertility
7. Research shines spotlight on a key player in the dance of chromosomes
8. Pot bellies linked to early signs of cardiovascular disease
9. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
10. Immune deficiency linked to a type of eye cancer
11. Drop in breast cancer incidence linked to hormone use, not mammograms
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chromosome Linked to Diabetics' Heart  Risks
(Date:8/28/2014)... CA (PRWEB) August 28, 2014 MarijuanaDoctors.com ... California physician, James Patel M.D. of Livermore, California. As ... best and most qualified physicians, and in accordance with ... our patients to Dr. Patel’s practice. , Initially finding ... a young age, Dr. Patel was shaped by his ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 The need for ... over the past few years. The new location - 4700 ... higher quality and larger office space than TLC had in ... , “We are pleased about our new location because it ... our suite will be double in size compared to the ...
(Date:8/27/2014)... Author and orthopedic surgeon William H. Simon’s ... thrilling adventures of sharp and witty Dr. Ham ... up for a new marketing push in the second ... , “Prescription: Murder” follows the adventures of Ham Marks, ... attempts and thwarting criminals. In the first novella, “Over ...
(Date:8/27/2014)... an innovative company that provides many kinds of top quality ... are now offered on its website. In addition, the firm ... that place an order for its newly released items can ... , The company’s senior spokesman was excited to talk ... and old customers can buy cheap bamboo panels on our ...
(Date:8/27/2014)... National Resident Matching Program International (NRMPI) ... Education in Europe (AMEE) Conference being held at the ... September 3, 2014. As an exhibitor, NRMPI will ... share the benefits of its matching services, and discuss ... countries throughout the world. , “Exhibiting at ...
Breaking Medicine News(10 mins):Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 2Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 3Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 4Health News:William H. Simon Launches New Marketing Campaign for Book 2Health News:BambooIndustry.com: Cheap Bamboo Panels for Clients Worldwide Offered Online 2Health News:National Resident Matching Program International (NRMPI) to Exhibit at the 2014 AMEE Conference 2
... CRANSTON, R.I., Nov. 27 A new, ... manufacturers (OEMs) on choosing the,right electronics manufacturing ... available free to download at, http://www.federalelec.com/medicalpaper ., ... need for consistent quality and,conformance to product ...
... 27, 2007, 4:00 p.m. E.S.T. - Positron emission tomography ... need for more accurate staging of lung cancer and ... published online today in Journal of National Cancer Institute. ... Cancer Disease Site Group of Cancer Care Ontarios Program ...
... Nov. 27 A new study that shows young ... for men has leveled off offers,strong evidence that preventive ... war on cardiovascular disease, said Christopher T. Fey, the,chairman ... released study published in Journal of the American College ...
... therapies, experts say , , TUESDAY, Nov. 27 (HealthDay News) ... doctors predict which postmenopausal women are likely to sustain ... algorithm includes 11 different factors -- such as age ... of different ethnic backgrounds. , "Knowing the 5-year ...
... Risk Elevated in Male BRCA Mutation Carriers , Men with ... of breast cancer than the general population. , Male breast cancer ... the U.S., and it is most common in men with a ... who carry mutations in the BRCA2 gene have a greater risk ...
... R.I. [Brown University] Heavy smoking and drinking are ... human papillomavirus type 16 (HPV16), a common strain of ... for head and neck cancer, which affects about 500,000 ... however, shows that alcohol and tobacco use doesnt further ...
Cached Medicine News:Health News:White Paper Details How to Choose the Right EMS Provider for Medical Products Outsourcing 2Health News:PET imaging significantly enhances standard imaging in lung cancer staging 2Health News:US Preventive Medicine(R) Says Study on Heart Disease-related Deaths Demonstrates Need for Preventive Medical Care 2Health News:US Preventive Medicine(R) Says Study on Heart Disease-related Deaths Demonstrates Need for Preventive Medical Care 3Health News:Criteria Predict Women's 5-Year Risk for Fracture 2Health News:Other Highlights in the Nov. 27 JNCI 2Health News:Other Highlights in the Nov. 27 JNCI 3Health News:Other Highlights in the Nov. 27 JNCI 4Health News:Drinking and smoking don't boost HPV-related cancer risk 2
(Date:8/27/2014)... Aug. 27, 2014 Reportlinker.com ... report is available in its catalogue: ... Application and Approval of Imported Medical ... (2014 Edition) ... Now, Chinese regulations on medical devices ...
(Date:8/27/2014)... Aug. 27, 2014  CVS Caremark (NYSE: ... new clinical affiliation with MedStar Health, a leading health ... and the Washington, DC ... health care services for patients. Through this clinical affiliation, ... clinical support, medication counseling, chronic disease monitoring and wellness ...
(Date:8/27/2014)... THOUSAND OAKS, Calif. , Aug. 27, 2014 /PRNewswire/ ... the U.S. Food and Drug Administration (FDA) has granted ... chronic heart failure (HF). Ivabradine is an oral drug ... ("funny" current) in the sinoatrial node, the body,s cardiac ... rate without negative effects on myocardial contractility or ventricular ...
Breaking Medicine Technology:Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 2Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 3Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 4Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 5Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 6Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 7Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 8Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 9Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 10CVS Caremark Announces New Clinical Affiliation with MedStar Health 2CVS Caremark Announces New Clinical Affiliation with MedStar Health 3FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 2FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 3FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 4FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 5FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 6FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 7
... April 1 , - Trial Results Expected Mid-2008, ... on vascular diseases, eye diseases and cancer, today announces ... MIVI III trial in the,United States. This study is ... vitrectomy (MIVI III - Microplasmin for Vitreous,Injection)., A ...
... As temperatures grow warmer,the American Heartworm Society (AHS) wants ... the heartworm disease risk it carries for pets., ... warmer months,when the mosquito population increases, the AHS recommends ... prevention every,month, forgetful pet owners will have their pets ...
Cached Medicine Technology:ThromboGenics Completes Patient Enrolment in the Phase IIb Trial of Microplasmin in Vitrectomy (MIVI III) 2ThromboGenics Completes Patient Enrolment in the Phase IIb Trial of Microplasmin in Vitrectomy (MIVI III) 3ThromboGenics Completes Patient Enrolment in the Phase IIb Trial of Microplasmin in Vitrectomy (MIVI III) 4Mosquito Season Approaching: American Heartworm Society Reminds Pet Owners of Risk 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: