Navigation Links
Chromosome Abnormality Tied to Autistic Behavior in Mice
Date:6/26/2009

Finding could help advance autism research in humans

FRIDAY, June 26 (HealthDay News) -- Mice with an extra chromosome region inherited from their fathers display many behaviors seen in people with autism, a finding that suggests that the same chromosome abnormality in humans is one cause of autism, according to Japanese scientists.

The mice will be an important tool in efforts to develop treatments for autism, the researchers from Hiroshima University say. Their report appears in the June 26 issue of the journal Cell.

The duplicated chromosomal region in mice is the equivalent of human chromosome 15q11-13, which is duplicated in about 5 percent of all people with autism. It is believed that chromosomal abnormalities account for 10 to 20 percent of autism cases, according to a news release from the journal's publisher, Cell Press. So far, duplication of chromosome 15q11-13 is the only recurrent aberration connected to autism.

The mice with an inherited duplication of a region on their chromosome 7 showed autism-like behaviors, such as poor social interaction, behavioral inflexibility, abnormal vocalizations and anxiety, the researchers found.

"The link between social behaviors in rodents and social behavior in humans is difficult to establish," the study authors concluded. "Our model mouse will be valuable not only for therapeutic studies but also provides a starting point for more detailed genetic analysis directed toward understanding the etiology of developmental brain disorders."

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about autism.



-- Robert Preidt



SOURCE: Cell Press, news release, June 25, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Grant Supports Study of Abnormal Ring-Shaped Chromosomes
2. Optherion Licenses Worldwide Rights to Develop Age-Related Macular Degeneration Diagnostics Based on Chromosome 10 Genetic Variations
3. Herceptin helps women with multiple chromosomes containing HER2 gene, study finds
4. Chromosome Abnormalities Raise Risk for Autism
5. Missing Chromosome Improves Response to Brain Tumor Treatment
6. Penn researchers identify first sex chromosome gene involved in meiosis and male infertility
7. Research shines spotlight on a key player in the dance of chromosomes
8. Chromosome Linked to Diabetics Heart Risks
9. CSHL scientists discover link between control of chromosome duplication and segregation
10. Prescription Copay Assistance for Patients taking Gleevec or Tasigna for Philadelphia chromosome-positive Chronic Myelogenous Leukemia (Ph+ CML)
11. Immune cells from patients with rheumatoid arthritis have prematurely aged chromosomes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chromosome Abnormality Tied to Autistic Behavior in Mice
(Date:4/28/2017)... ... April 28, 2017 , ... Somnoware, a leading ... Word(TM) Online(TM), which enables sleep physicians to create and edit their interpretation reports. ... and provides a familiar interface that does not require additional training to use. ...
(Date:4/28/2017)... Grants Pass, OR (PRWEB) , ... April 28, ... ... Adetutu Ijose, http://www.foodsthathealdaily.com , http://www.wiredlifesolutions.com , “Computers are everywhere and ... Kleyne Hour Power of Water, Global Climate Change and Your Health on Voice ...
(Date:4/28/2017)... ... April 28, 2017 , ... The Texas Cord Blood ... to the labor and delivery team at Women’s Hospital at Renaissance in Edinburg for ... birth at the hospital and decide to donate. , “Women’s Hospital at Renaissance ...
(Date:4/28/2017)... ... ... Pastor and Overseer at The House of Yahweh in Abilene, Texas, has published a new ... not. Yisrayl says with so many titles and names for the Creator, it’s hard ... a little Scripture, backed with a lot of research, the truth is undeniable. , ...
(Date:4/28/2017)... , ... April 28, 2017 , ... NuevaCare, a leading ... diverse as Millbrae, Burlingame, and Palo Alto, is proud to announce information upgrades to ... to bookmark and read organized content on topics such as home care (generally) as ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017  RXi Pharmaceuticals Corporation (NASDAQ: RXII), ... address significant unmet medical needs, today announced that ... consumer product development program, based on its proprietary ... Investigative Dermatology (SID) 76 th Annual Meeting.  ... the sciences relevant to skin health and disease ...
(Date:4/20/2017)... --  ZappRx, Inc ., a digital health company focused on ... it closed $25 million in Series B funding led by ... Seattle that is part of a ... B round included participation from SR One , who ... (formerly Google Ventures). As part of the financing, ...
(Date:4/20/2017)... , April 20, 2017 Eyevensys, ... the first non-viral gene expression technology that enables the ... eye to address a wide range of ophthalmic diseases, ... and Healthcare products Regulatory Agency (MHRA) to advance its ... ...
Breaking Medicine Technology: