Navigation Links
Chopped up proteins trigger autoimmunity
Date:1/24/2008

He has also discovered that PM/Scl-75, one of the components from which the exosome is built, is cut as soon as a cell dies. Finally, Schilders has identified an exosome-associated protein that is also frequently recognised by antibodies. These antibodies possibly form an interesting additional marker for the diagnosis of the PM/Scl overlap syndrome.

In people who suffer from an autoimmune disease, the immune system has been disrupted to such an extent that it produces antibodies against a persons own substances. In polymyositis/sclerodermia (PM/Scl) overlap syndrome these antibodies are targeted at the exosome. This complex of proteins is involved in the degradation of RNA in the cell. RNA forms an essential link in the flow of information in a cell and, therefore, a strict control over the degradation of RNA is vitally important.


'/>"/>

Contact: Dr. G.W. Schilders
g.schilders@ncmls.ru.nl
Netherlands Organization for Scientific Research
Source:Eurekalert

Page: 1

Related medicine news :

1. The Handbook of Proteins
2. New Proteins That Help HIV Grow Identified
3. Scientists get first look at how water lubricates proteins
4. 2 proteins may be survival markers in some breast cancers
5. Immune Proteins Warn of Early Lung Cancer
6. Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
7. Heat shock proteins are co-opted for cancer
8. Penn study finds pro-death proteins required to regulate healthy immune function
9. Molecule May Trigger Psoriasis
10. Protein power: Researchers trigger insulin production in diabetic mice
11. Scripps research scientists discover chemical triggers for aggression in mice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... for mental health professionals, announced today its affiliation with Tennessee Counseling Association. ... solutions to the network of the Tennessee Counseling Association, adding exclusive benefits and ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, and ... in the eye of the beholder, according to experts who offered insights and commentary ... of Managed Care. For the full issue, click here . , For the ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified ... be personalized through a fitness app. The fitness app plans to fix the two major ... only offer a one size fits all type program , They don’t eliminate ...
(Date:6/25/2016)... ... 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to ... a new, often overlooked aspect of head lice: the parasite’s ability to live away from ... common occurrence, but a necessary one in the event that lice have simply gotten out ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 ... care operating models within the health care industry is ... financial efficiency , Deloitte offers a suite of ... business issues impacting efficient cost optimization: labor resource analysis, ... These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... Mass. , June 24, 2016   ... Spaulding Rehabilitation Network,s Dean Center for Tick ... Physical Medicine and Rehabilitation, MIT Hacking Medicine, University ... for Innovation, today announced the five finalists of ... for Lyme disease.  More than 100 scientists, clinicians, ...
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
Breaking Medicine Technology: