Navigation Links
Cholesterol Drug Shows Promise in Early Research
Date:11/15/2011

cy and safety of evacetrapib," the study authors added.

The most recent testing of evacetrapib involved almost 400 patients who, between April 2010 and January 2011, were being treated for having either elevated bad cholesterol or low good cholesterol levels in health centers across the United States and Europe.

The patients were divided into several groups. For about three months, some received various dosages of evacetrapib alone. Others received one of several statins, either alone or in combination with evacetrapib. Still others were given sugar pills (placebo pills).

The results: after 12 weeks of treatment, the team observed that patients receiving evacetrapib alone experienced a boost in good cholesterol of between roughly 54 and 129 percent. Among this group, bad cholesterol also dropped, between approximately 14 to 36 percent.

The investigators also found that when given a combination therapy involving both evacetrapib and a statin, patients experienced even greater reductions in bad cholesterol. This tandem approach, however, did not produce better results than evacetrapib alone in terms of raising good cholesterol.

Commenting on the study, Dr. Murray A. Mittleman, director of the Cardiovascular Epidemiology Research Unit with the Beth Israel Deaconess Medical Center at Harvard Medical School in Boston, approached the findings with caution.

"This class of medicines is interesting because they can raise good cholesterol, often quite markedly," Mittleman said. "And most studies show that this can prevent heart attacks. And at this point we don't have very many good drugs that can accomplish this."

"But of course, work with an earlier agent showed an increase in adverse events, and the development of that drug had to be stopped prematurely," Mittleman noted. "So while the initial findings with this drug are interesting, a lot of work still remains to find out if it does what we hope it will do, or if in fact it will
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. New medication increases HDL cholesterol and decreases LDL cholesterol levels
2. Shot Might One Day Help Lower Cholesterol
3. New Guidelines Urge Cholesterol Check for All Kids Ages 9 to 11
4. Novel therapeutic target identified to decrease triglycerides and increase good cholesterol
5. FDA Approves First Combo Drug for Diabetes, Cholesterol
6. Raising good cholesterol levels reduces heart attack and stroke risk in diabetes patients
7. Cholesterol Deposits Around Eyes Linked to Heart Risk
8. Targeting cholesterol may help slow glioblastoma
9. Starving cancer cells of cholesterol might offer a new way to treat brain tumors
10. Targeting cholesterol to fight deadly brain cancers
11. High Cholesterol Might Be Linked to Alzheimers Disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cholesterol Drug Shows Promise in Early Research
(Date:8/3/2015)... ... August 03, 2015 , ... Novation, the nation’s largest ... pharmacogenetic lab testing and precision medicine solutions that can help pharmacists and other ... more than 8.6 million adverse drug events are reported in the U.S. ...
(Date:8/3/2015)... ... 2015 , ... Dental practice in Los Angeles , Sunset Plaza Dental, ... that general health emergencies, such as broken arms or a heart attack, should be ... turn to during a dental emergency. This is important, because dental trauma is extremely ...
(Date:8/3/2015)... ... August 03, 2015 , ... Results of a comprehensive ... Healthcare Research and Policy Analysis show widespread support for the U.S. Affordable Care ... or strongly agreed that the controversial law passed in 2010 had “more good ...
(Date:8/3/2015)... (PRWEB) , ... August 03, 2015 , ... The U.S. ... under the chin. Kybella is similar to deoxycholic acid, which occurs naturally in the ... the main options to treat this area of the body. These are invasive procedures ...
(Date:8/3/2015)... ... 03, 2015 , ... Illinois Health & Science (IHS) has completed the purchase ... includes all of IBAM NA’s cyclotron sites and research and development facilities. ... business, as well as a large manufacturing hub in Noblesville, Indiana,” said Ken Smithmier, ...
Breaking Medicine News(10 mins):Health News:Novation Awards Genelex First Group Purchasing Agreement for Pharmacogenetic Testing and Precision Medicine Software 2Health News:Novation Awards Genelex First Group Purchasing Agreement for Pharmacogenetic Testing and Precision Medicine Software 3Health News:Los Angeles Dental Practice, Sunset Plaza Dental, Now Offers Emergency Dental Services 2Health News:Los Angeles Dental Practice, Sunset Plaza Dental, Now Offers Emergency Dental Services 3Health News:Survey Finds Support for the Affordable Care Act Among Physician Leaders 2Health News:Survey Finds Support for the Affordable Care Act Among Physician Leaders 3Health News:Dr. Ava Shamban to Offer the New Double Chin Treatment Kybella 2Health News:Dr. Ava Shamban to Offer the New Double Chin Treatment Kybella 3Health News:Illinois Health & Science Expands Nuclear Medicine Footprint With Purchase of IBA Molecular North America, Inc. 2
... Palomar Medical Technologies, Inc. (Nasdaq: PMTI ), ... treatments, will hold its quarterly conference call of its 2009 ... 11:30 AM Eastern Time. If you would like to participate, ... that day. The telephone replay will be available one hour ...
... , TAMPA, Fla., July 23 Bay Area ... chemical drugs and armed himself with a movie to help ... preventable illness, Burton found an alarming connection between America,s food ... Now he,s going to tell the world what he found. ...
... what a tale my thoughts could tell" Gordon Lightfoot ... and some new businesses, are banking on a brain imaging ... hidden thoughts, such as lies, truths or deep desires. ... Rutgers University provides evidence that fMRI can be used in ...
... risen over recent years. This is fact, but what is ... health centres have shown that family conflict is not a ... Primaria are striking: in Spain, 24% of women take antidepressants ... of psychopharmaceuticals is often related to family or work-related problems. ...
... , PRINCETON, N.J., July 23 The National ... several member associations today urged President Obama and members of Congress to ... most pervasive and costly diseases, a priority in reforming the U.S. healthcare ... to the President and lawmakers, NCDP said a national response to diabetes ...
... , BATESVILLE, Ind., July 23 Hill-Rom Holdings, Inc.,s, ... be issued Thursday, August 6, 2009. You are invited to participate ... a.m. EDT. , Earnings Release: Hill-Rom Holdings, ... 2009 will be released to the public after the NYSE close on ...
Cached Medicine News:Health News:Palomar Medical Technologies To Host Second Quarter 2009 Financial Results Conference Call and Webcast on July 30, 2009 2Health News:Nurse Turned Filmmaker Makes Lifesaving Film 2Health News:Can brain scans read your mind? 2Health News:Can brain scans read your mind? 3Health News:Almost 1 quarter of Spanish women take antidepressants 2Health News:NCDP Health Care Reform Recommendations Advocate for Diabetes Prevention, Treatment and Care 2Health News:NCDP Health Care Reform Recommendations Advocate for Diabetes Prevention, Treatment and Care 3Health News:Hill-Rom Holdings, Inc. Invites You to Join Its Fiscal 2009 Third Quarter Earnings Webcast 2
(Date:8/3/2015)... 3, 2015  Array BioPharma Inc. (NASDAQ: ... quarter and full year of its fiscal year ... Chief Executive Officer of Array, noted, "Binimetinib and encorafenib, ... on track for regulatory submissions in 2016. Additional ... and BRAF-mutant colorectal cancer further validate the value ...
(Date:8/3/2015)... Aug. 3, 2015  Charleston Laboratories, Inc., an ... second clinical development program with a Phase 1 ... CL-H1T contains fast-dissolving promethazine and sumatriptan.  ... a treatment for migraine headache pain and migraine-induced ... patients with migraine headaches also suffer from nausea ...
(Date:8/3/2015)... FLORHAM PARK, N.J. , Aug. 3, ... met its primary and secondary endpoints in a phase ... constipation (OIC) in adult patients with chronic non-cancer pain. ... antagonist (PAMORA). This is the third Phase III trial ... endpoints. Study results showed that a 0.2 ...
Breaking Medicine Technology:Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 2Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 3Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 4Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 5Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 6Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 7Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 8Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 9Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 10Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 11Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 12Charleston Laboratories, Inc. Initiates Patient Enrollment in a Phase 1 Study of Charleston's Second Product, CL-H1T 2Naldemedine Meets Primary Endpoint In Phase 3 Study For The Treatment Of Opioid-Induced Constipation 2Naldemedine Meets Primary Endpoint In Phase 3 Study For The Treatment Of Opioid-Induced Constipation 3Naldemedine Meets Primary Endpoint In Phase 3 Study For The Treatment Of Opioid-Induced Constipation 4
... /PRNewswire-Asia/ -- Simcere Pharmaceutical Group (NYSE: SCR ... specializing in the development, manufacturing, and marketing of branded ... annual general meeting of shareholders (the "Meeting") will be ... Beijing time. The meeting will be held at No.699-18, ...
... /PRNewswire-iReach/ -- Global Information Inc. is pleased to ... Therapy market: Global Protein Therapeutics Market ... become one of the most effective clinical methods to ... metabolic disorders. While worldwide healthcare spending has decline in the ...
Cached Medicine Technology:Simcere Pharmaceutical Group Provides Notice of Annual General Meeting 2New Forecast Shows Global Protein Therapeutics Market to Reach $143.4 Billion by 2015 2
This portable resource provides definitions for medical acronyms and abbreviations....
Stedman's Medical Dictionary includes charts and tables and navigation and search tools....
With Skyscape's smARTlink technology, Tabers can cross-index with other clinical and drug prescription products from Skyscape to provide an integrated source of clinical information....
CPTMeister is a coding reference based on the Physicians' Current Procedural Terminology (CPT) codes developed by the American Medical Association. It is an iSilo document composed of more than 2,000...
Medicine Products: