Navigation Links
Cholesterol Drug Shows Promise in Early Research
Date:11/15/2011

TUESDAY, Nov. 15 (HealthDay News) -- Preliminary trials indicate that a new drug designed to simultaneously boost good cholesterol while lowering bad cholesterol shows considerable promise, both on its own and in combination with standard statin medications.

The drug evacetrapib is part of a class of so-called "cholesteryl ester transfer protein (CETP) inhibitors."

Evacetrapib is the second CETP medication to undergo testing as a means to lower "bad" low-density lipoprotein cholesterol while raising "good" high-density lipoprotein cholesterol.

Testing of the first drug in this class -- Pfizer's torcetrapib -- ended badly. A 15,000-person trial of torcetrapib conducted several years ago revealed that the medication (administered in combination with the statin Lipitor) was associated with an elevated risk for cardiovascular complications and even death.

In that case, the trial was halted mid-stream and all patients were taken off the combination therapy immediately.

However, the failure of that drug has not discouraged researchers from continuing to explore the potential of CETP therapies. What's more, work with evacetrapib to date has unearthed no significant side effects, while suggesting that the drug can benefit patients both as an individual treatment and as part of a two-pronged approach in tandem with statins, according to the report published Nov. 16 in the Journal of the American Medical Association.

"These preliminary findings suggest that evacetrapib could be administered with statins and may yield potentially clinically important incremental effects on lipoproteins," Stephen J. Nicholls, of the department of cardiovascular medicine and the coordinating center for clinical research at the Cleveland Clinic in Ohio, and colleagues noted in a journal news release.

"The results of the current study provide the foundation for a large phase 3 clinical trial designed to assess the effica
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. New medication increases HDL cholesterol and decreases LDL cholesterol levels
2. Shot Might One Day Help Lower Cholesterol
3. New Guidelines Urge Cholesterol Check for All Kids Ages 9 to 11
4. Novel therapeutic target identified to decrease triglycerides and increase good cholesterol
5. FDA Approves First Combo Drug for Diabetes, Cholesterol
6. Raising good cholesterol levels reduces heart attack and stroke risk in diabetes patients
7. Cholesterol Deposits Around Eyes Linked to Heart Risk
8. Targeting cholesterol may help slow glioblastoma
9. Starving cancer cells of cholesterol might offer a new way to treat brain tumors
10. Targeting cholesterol to fight deadly brain cancers
11. High Cholesterol Might Be Linked to Alzheimers Disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cholesterol Drug Shows Promise in Early Research
(Date:4/24/2014)... Ill. It is better to give than to receive ... giving, a new study suggests. , The study found that ... as giving their money to family members, are less likely ... from taking risks or keeping the money for themselves. , ... the National Academy of Sciences . , The study focused ...
(Date:4/24/2014)... Ore. An Oregon State University researcher has found ... of the symptoms of autism spectrum disorder in very ... be the first to show a direct relationship between ... fine and gross motor skills should be included in ... MacDonald, an assistant professor in OSU,s College of Public ...
(Date:4/24/2014)... University of York reveals that a process that forms ... system may also play a pivotal role in the ... by Dr Will Brackenbury, a Medical Research Council Fellow ... how voltage-gated sodium channels assist in the metastasis of ... of excitable cells, such as neurons, where they are ...
(Date:4/23/2014)... 2014 Pregnant immigrants from Sub-Saharan Africa, Latin ... during pregnancy, according to new research from St. ... the British Journal of Obstetrics and Gynaecology ... rates among immigrants and native-born women in six ... Sweden, Spain (Catalonia and Valencia) and the United ...
(Date:4/23/2014)... National Institute of Arthritis and Musculoskeletal and Skin Diseases ... Ross Prize in Molecular Medicine, conferred by the Feinstein ... award will be given on June 9 at the ... scientific presentations by Dr. O,Shea and other prominent researchers. ... , The award, which includes a $50,000 prize from ...
Breaking Medicine News(10 mins):Health News:Study: Altruistic adolescents less likely to become depressed 2Health News:Motor skill deficiencies linked to autism severity in new research 2Health News:Breast cancer replicates brain development process 2Health News:Pregnancy complications may be more common in immigrants from certain regions 2Health News:NIH scientist to receive Ross Prize in Molecular Medicine 2
... , AUDUBON, Pa., June 2 Globus Medical, Inc., the ... announced the launch of the COALITION(TM) ACDF Spacer System. ... provide the biomechanical strength of a traditional ACDF with less ... , The COALITION(TM) technology combines a PEEK interbody ...
... June 2 Cordex Pharma, Inc. (OTC Bulletin Board: ... Administration (FDA) has approved the design of pivotal, Phase ... an antiarrhytmic drug for the acute treatment of patients ... Assessment (SPA) process. , , ATPace(TM) is ...
... iMedica Corporation , a leading developer ... participation in the American College of Physicians ... Designed to assist physicians in choosing the best EHR for ... standards. The EPP provides detailed information to ACP members who ...
... Planned Spinoff of CareFusion Corporation , , DUBLIN, Ohio, ... and services that improve the safety and productivity of health ... quarterly dividend to $0.175 per share, or $0.70 per share ... announcement is particularly meaningful in that it comes in advance ...
... Medical, Inc. (Nasdaq: SLTM ), a global leader ... present at the Eight Annual Needham Life Sciences Conference at ... scheduled for 9:30 a.m. Eastern Time on Thursday, June 11, ... Officer, will review the company,s business strategy and recent corporate ...
... if you can find one , , BALTIMORE, June 2 ... late February, the Centers for Disease Control (CDC) says there are ... time of year. According to health officials, it is not too ... , Those who are in higher risk groups should receive ...
Cached Medicine News:Health News:Globus Medical Announces Launch of COALITION(TM) ACDF Spacer System 2Health News:Cordex Receives Special Protocol Assessment Approval from FDA for ATPace(TM) 2Health News:Cordex Receives Special Protocol Assessment Approval from FDA for ATPace(TM) 3Health News:Cordex Receives Special Protocol Assessment Approval from FDA for ATPace(TM) 4Health News:iMedica Participates in American College of Physicians' EHR Partners Program 2Health News:iMedica Participates in American College of Physicians' EHR Partners Program 3Health News:Cardinal Health Increases Quarterly Dividend By 25 Percent 2Health News:Cardinal Health Increases Quarterly Dividend By 25 Percent 3Health News:Cardinal Health Increases Quarterly Dividend By 25 Percent 4Health News:Solta Medical, Inc. to Present at 8th Annual Needham Life Sciences Conference 2Health News:Seasonal Flu Lingers 2
(Date:1/15/2014)... Jan. 15, 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic ... . (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) ... policy support, China,s orthopedic instrument ... total market size rising from 3.28 billion yuan in ...
(Date:1/15/2014)... , Jan. 15, 2014 AARP Foundation today announced ... older adults suffering from the severe cold weather that has ... committed to helping those in need; so to support these ... contributions up to $250,000, which could mean up to $500,000 ...
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ) announces ... condition to the announced tender offer for all of the outstanding ... result of the waiver, the transaction is no longer conditional on ... January 24, 2014 following the currently scheduled expiration time, subject to ...
Breaking Medicine Technology:Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3
... YORK, Feb. 15, 2012 Delcath Systems, Inc. (NASDAQ: ... ( Instituto Europeo di Oncologia – IEO) introduced ... a Feb. 15 press conference and discussed the status ... CHEMOSAT is a critical new treatment option for patients ...
... ERT (NASDAQ: ERT ) announced today that it ... year 2011 Monday, February 27, after the market closes. After ... 5:00 PM ET that day. For the conference ... United States or 1-412-858-4600 when calling internationally. There will be ...
Cached Medicine Technology:Delcath CHEMOSAT Presented as Innovative Treatment for Liver Metastases by European Institute of Oncology 2Delcath CHEMOSAT Presented as Innovative Treatment for Liver Metastases by European Institute of Oncology 3Delcath CHEMOSAT Presented as Innovative Treatment for Liver Metastases by European Institute of Oncology 4ERT to Report Fourth Quarter and Full Year 2011 Operating Results 2
... Instruments incorporate a layered design unique in ... monitored to prevent stray electrosurgical burns along ... insulation failure or capacitive coupling; a well-documented ... into all AEM Instruments provides a neutral ...
... 5mm AEM Laparoscopic Instruments incorporate a layered ... are shielded and monitored to prevent stray ... instrument caused by insulation failure or capacitive ... protective shield built into all AEM Instruments ...
... The 5mm AEM Laparoscopic Instruments incorporate a ... Instruments are shielded and monitored to prevent ... the instrument caused by insulation failure or ... The protective shield built into all AEM ...
... Instruments incorporate a layered design unique in ... monitored to prevent stray electrosurgical burns along ... insulation failure or capacitive coupling; a well-documented ... into all AEM Instruments provides a neutral ...
Medicine Products: