Navigation Links
Chinese systemic lupus erythematosus data reveal differences in epidemiology across continents
Date:6/18/2010

Rome, Italy, Friday 18 June 2010: The Chinese Systemic Lupus Erythematosus (SLE) Treatment and Research Group (CSTAR) announced interim epidemiological information on SLE patients in China today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. Robust data on SLE patients has been scarce to date; but now CSTAR provides the first online registry of this magnitude in China. To date the registry has collated data from 2,104 SLE patients across 30 Chinese provinces.

An initial comparative analysis of CSTAR data with other similarly sized cohort analyses undertaken across the USA, Europe and Malaysia revealed the following key differences in the main characteristics and disease manifestations between Chinese SLE patients and those studied in the comparative cohorts:

Over half (57.4%) of Chinese SLE patients present with concurrent haematological disorders compared with 48% of Malaysian patients and only 18.2% of European patients Almost half (45.8%) of Chinese patients are also diagnosed with kidney disease compared with 27.9% of European patients and only 7.4% of Malaysian patients Conversely, neurological manifestations are only seen in 4.5% of Chinese SLE patients compared with 19.4% of European patients and 12.1% of US patients.

"Other SLE registries exist across the world, but this is a first for a nation with the largest global population. The research group set out to clarify the epidemiology of SLE in China and provide valuable information on the manifestations, morbidity and mortality of SLE patients," said Professor Xiaofeng Zeng, Peking Union Medical College Hospital, China, and lead researcher of the study. "Given that the results suggest many differences in experience of disease between ethnicities, this essential information on this complex disease will provide a vital insight to help patients in the future, and contribute to the international knowledge base on SLE."

The CSTAR registry collated data from 106 specialist rheumatology centres and study leaders ensured that all centres utilised the same protocol-directed methods for data collection, including demographic data, clinical history and laboratory and radiological examinations. Patients included in the registry were required to meet four or more of the American College of Rheumatology criteria for the classification of SLE. Evaluations of disease activity were made through completion of the SLE Disease Activity Index (SLEDAI), the British Isles Lupus Assessment Group (BILAG) disease activity index and the physician's global assessment (PGA) of SLE activity. Biological specimens and patient autoantibody profiles were also gathered.

CSTAR is supported by the Chinese National Key Technology Research & Development Programme.


'/>"/>

Contact: Caroline Butt
eularpressoffice@uk.cohnwolfe.com
44-778-927-0392
European League Against Rheumatism
Source:Eurekalert

Related medicine news :

1. Older Chinese consumers perceive themselves younger than actual age
2. U.S. FDA Removes Many Chinese Candies From Import Alert 99-30 Based on Insufficient Evidence, According to FDAImports.com, LLC
3. Springer Asia launches Chinese medicine textbook series in English
4. Safety and diagnosis yield of colonoscopy in Hong Kong Chinese children
5. Tickerspy.com Announces New Stock Index Tracking Chinese Healthcare Stocks
6. Chinese New Year Banquets Bring Good Luck, Happiness and Prosperity for the New Year
7. 2000th Free Cleft Lip/Palate Surgery Performed During Successful Chinese Mission
8. Urinary tract cancer associated with Chinese herbal products containing aristolochic acid
9. Chinese-American and Korean-American women at highest risk for diabetes in pregnancy
10. Luckey & Mullins Joins with Other National Construction Defect Law Firms to Form Chinese Drywall Legal Network
11. Genealogy may affect clinical differences in systemic lupus erythmatosus patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2017)... PA (PRWEB) , ... May 21, 2017 , ... Following ... 2012, New York became the first state to require that hospitals follow a protocol ... controversy in the medical community as to whether such steps would have saved Rory ...
(Date:5/19/2017)... ... 19, 2017 , ... DMG Productions is proud to announce ... Ed Begley, Jr., airing fourth quarter 2017 on FOX Business. , Based in ... supplement made from naturally occurring ingredients. Innovations will enlighten viewers on RawTrition’s all-in-one ...
(Date:5/19/2017)... ... May 19, 2017 , ... The Miller Agency, ... to families and business owners in the region, is embarking on a cooperative ... and their families. , Multiple sclerosis (MS) is a demyelinating disease that affects ...
(Date:5/19/2017)... ... May 18, 2017 , ... ML Billing, 2016 ... specialties and sizes and specializes in large group practices, is pleased to announce their ... it has also set the standard in all aspects of full-service medical billing. This ...
(Date:5/18/2017)... ... 18, 2017 , ... Dr. Kim Ross supports Stroke Awareness Month by now ... link between this condition and serious systemic health conditions including heart disease and stroke. ... in Annapolis, MD, and seeking treatment with Dr. Ross immediately may prevent bacteria from ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... 2017  A new tight-tolerance microextrusion medical tubing ... materials, is being launched by Natvar, a Tekni-Plex ... in recent years to service a wide variety ... More expensive materials such as glass and fluoropolymers ... to their ability to consistently hold tolerances. This ...
(Date:5/3/2017)... Calif. , May 3, 2017 ... of any hospital or healthcare facility. Commonly referred ... room is equipped with diagnostic imaging technology to ... of the heart. In these spaces, a team ... catheterization, balloon angioplasty, percutaneous coronary intervention, congenital heart ...
(Date:5/3/2017)... , May 3, 2017  Getinge, a ... contribute to quality enhancement and cost efficiency within ... a study of contemporary practice demonstrating that intra-aortic ... therapy for critically ill patients. The single-center, retrospective, ... newer large volume MEGA ® 50cc intra-aortic ...
Breaking Medicine Technology: