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China Documents First Case of Tick-Borne Disease Spread
Date:11/18/2008

Human-to-human transfer caused by contact with blood, respiratory secretion

TUESDAY, Nov. 18 (HealthDay News) -- The first Chinese case of a tick-borne disease called granulocytic anaplasmosis (HGA), which then led to person-to-person transmission of the disease, is described in a study by researchers at China's National Institute of Communicable Disease Control and Prevention.

It's the first known report of human-to-human transmission of HGA.

HGA was identified in the United States in 1990 and in Europe in 1997. The number of infections reported each year in the United States is rising, with infection rates in endemic areas as high as 15 percent to 36 percent.

The Chinese team launched an investigation after a cluster of HGA cases occurred in health-care workers and family members following exposure to a patient with disease symptoms consistent with HGA. The female patient was bitten by a tick 12 days before the onset of fever and hemorrhage. She was admitted to a regional hospital in Anhui province, and later died. Of 28 people who had close contact (20 inches or less) with the patient during the final 12 hours of her life, nine became infected with the type of bacteria (A. phagocytophilium) that causes HGA. All nine reported contact with the patient's blood, and seven had contact with her respiratory secretions.

"The most remarkable aspect of these cases was that transmission was very unlikely to be tick-borne, but was closely associated with blood or respiratory secretion from hemorrhage," the researchers wrote. "Although it is likely that routine blood and fluid precautions will protect against such future events, strict adherence to protective protocols is mandatory even if communicability is deemed unlikely."

The researchers added that the lessons of this case study "remain relevant to the daily hospital and health care unit operations to prevent any additional [hospital] outbreak
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China Documents First Case of Tick-Borne Disease Spread
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