Navigation Links
Children's Hospital study finds African-Americans more distrusting of research than whites
Date:2/3/2009

Distrust toward medicine and research plays a significant role in African-Americans' lack of participation in clinical trials, according to a study by researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh Graduate School of Public Health.

African-Americans are significantly underrepresented in clinical research. A recent study published in the February issue of Archives of Pediatrics & Adolescent Medicine addresses the racial differences in parental trust toward medicine and research and their implications for enrollment of children into clinical research. The researchers found that enrollment of children into clinical research studies depends on parental attitudes, beliefs and expectations.

In a research survey of 190 parents (140 African-American and 50 white) of patients seen at Children's Hospital's Primary Care Center, African-American parents were twice as likely to be distrusting of medical research as white parents. This study was conducted by Kumaravel Rajakumar, MD, a pediatrician in Children's Hospital of Pittsburgh's Division of General Academic Pediatrics, in collaboration with Stephen Thomas, PhD, the Philip Hallen Professor of Community Health and Social Justice and director of the Center for Minority Health in the Graduate School of Public Health at the University of Pittsburgh.

"Parental distrust toward medicine and research can be a barrier for enrollment of children in clinical research studies. The higher levels of distrust among African-American parents can mean that they are less likely to enroll their children in clinical trials, which can have profound implications for eliminating racial and ethnic health disparities, as it impacts the extent to which research findings can be applied to the general population including minorities," said Dr. Rajakumar, also an assistant professor of Pediatrics in the University of Pittsburgh School of Medicine. "Our study also found that financial and other incentives would only be moderately effective in increasing participation. As a medical community, we need to develop better strategies for overcoming the distrust of African-American parents to help achieve adequate participation of African-American children in clinical research."

As compared with white parents, African-American parents:

  • More often reported distrust of medical research, when questions assessing trust were combined and analyzed (67 percent vs. 50 percent)
  • More often believed that physicians prescribe medications as a way of experimenting on unknowing patients (40 percent vs. 28 percent)
  • Were more likely to believe that medical research involves too much risk to the participant (46.8 percent vs. 26 percent), that physicians will not make full disclosures regarding their child's participation (24.6 percent vs. 10 percent) and that research participants would be favored and receive better medical care (48.6 percent vs. 28 percent)

Education level also was associated with distrust, with high distrust scores among 74 percent of those with less than a high school education vs. 44 percent of college graduates. However, race remained associated with higher levels of distrust even after the researchers controlled for education, with African-American parents being two times more likely of being distrusting compared with white parents.

"Race matters," Dr. Thomas said. "It is important for the biomedical research community to acknowledge that African-American distrust toward medicine and research is not irrational; on the contrary, it reflects the legitimate discontent of far too many black families who experience racial discrimination when seeking medical care along with the clear and convincing evidence of racial disparities in their health status compared with whites'. The experience of discrimination is not limited to one individual or one generation but is passed on through word of mouth, keeping alive the cultural memory of how medical science was used to justify the racial inferiority of African-Americans."

The authors conclude that the use of culturally appropriate recruitment materials, as well as using research assistants with similar racial and cultural backgrounds as the subject population, can help provide accurate information and quell parental distrust toward clinical research. Additionally, the establishment of community research advisory boards, which provide feedback at all stages of a research study, as has been done in Pittsburgh, is another means to ensure that minority community members participate and disseminate information about studies while protecting the interests of research subjects and potentially reducing distrust.


'/>"/>

Contact: Marc Lukasiak
marc.lukasiak@chp.edu
412-692-7919
Children's Hospital of Pittsburgh
Source:Eurekalert

Related medicine news :

1. Nautica Malibu Triathlon Presented by Toyota Raises $718,000 for Childrens Hospital Los Angeles Pediatric Cancer Research
2. Childrens Hospital Los Angeles Turns Off the Tap With Green Earth Waterless Carwash
3. Siegel+Gale Designs New HOPE Portal for Childrens Hospital Los Angeles
4. Jessica Biel and Make The Difference Network Bring Holiday Cheer to Childrens Hospital Los Angeles
5. National Childrens Study Begins Recruiting
6. New research explores newborn in-hospital weight loss
7. NYC-area 1st: Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement
8. Norwalk virus: Cruise ship illness challenging and costly to hospitals, too
9. Glades General Hospital First in Palm Beach County to Provide On-Site Electronic Birth Registration
10. Billy Graham Home After Hospitalization:
11. Alvarado Hospital Files Countersuit Against Blue Shield
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2017)... Fl (PRWEB) , ... April 25, 2017 , ... There ... Memorial Regional Hospital, according to a special report in the May issue of Consumer ... its highest quality ranking for results achieved during and after coronary bypass and ...
(Date:4/24/2017)... ... 2017 , ... Emmanuel College is introducing enhancements to its ... in the fall of 2017, Emmanuel’s program will allow registered nurses (RN)s to earn ... and for as little as $14,528. These changes will enable nurses to complete their ...
(Date:4/24/2017)... ... 2017 , ... The Santana Telehealth Project was honored with the 2017 ATA ... Telemedicine Association’s annual conference, on April 23 in Orlando, FL. , “I am proud ... lives of the poor and underserved in other parts of the world,” said Jonathan ...
(Date:4/24/2017)... , ... April 24, 2017 , ... ... Research Association’s Outstanding Public Communication of Education Research Award. The award honors scholars ... education communities. It recognizes a scholar who has demonstrated the capacity to deepen ...
(Date:4/24/2017)... Calif. (PRWEB) , ... April 24, 2017 , ... The ... $1.6 million in charitable dental services to 1,961 people during the April 22-23 event ... at no charge to Californians who experience barriers to care, CDA Cares educates the ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 19, 2017 Global Surgical Drainage Device Market: ... used to remove excess liquid and air. The fluid ... bile or lymph. Surgical drains are used in a ... orthopedics surgery, cardiovascular surgery, neurosurgery, plastic surgery etc. Common ... prevent accumulation of fluid e.g. blood or pus. Surgical ...
(Date:4/19/2017)... Tenn. and DALLAS , April 19, 2017 ... announced that the first patients in Nashville ... device in the Lower Esophageal Sphincter Stimulation for GERD ... implantable device designed to provide long-term reflux control by ... GERD affects nearly 65 million people in ...
(Date:4/19/2017)... DIEGO , April 19, 2017  Sorrento ... an antibody-centric, clinical-stage biopharmaceutical company developing new treatments ... announced the closing of its previously announced underwritten ... stock at a public offering price of $2.00 ... and estimated offering expenses payable by Sorrento.  The ...
Breaking Medicine Technology: