Navigation Links
Children's Hospital study finds African-Americans more distrusting of research than whites

Distrust toward medicine and research plays a significant role in African-Americans' lack of participation in clinical trials, according to a study by researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh Graduate School of Public Health.

African-Americans are significantly underrepresented in clinical research. A recent study published in the February issue of Archives of Pediatrics & Adolescent Medicine addresses the racial differences in parental trust toward medicine and research and their implications for enrollment of children into clinical research. The researchers found that enrollment of children into clinical research studies depends on parental attitudes, beliefs and expectations.

In a research survey of 190 parents (140 African-American and 50 white) of patients seen at Children's Hospital's Primary Care Center, African-American parents were twice as likely to be distrusting of medical research as white parents. This study was conducted by Kumaravel Rajakumar, MD, a pediatrician in Children's Hospital of Pittsburgh's Division of General Academic Pediatrics, in collaboration with Stephen Thomas, PhD, the Philip Hallen Professor of Community Health and Social Justice and director of the Center for Minority Health in the Graduate School of Public Health at the University of Pittsburgh.

"Parental distrust toward medicine and research can be a barrier for enrollment of children in clinical research studies. The higher levels of distrust among African-American parents can mean that they are less likely to enroll their children in clinical trials, which can have profound implications for eliminating racial and ethnic health disparities, as it impacts the extent to which research findings can be applied to the general population including minorities," said Dr. Rajakumar, also an assistant professor of Pediatrics in the University of Pittsburgh School of Medicine. "Our study also found that financial and other incentives would only be moderately effective in increasing participation. As a medical community, we need to develop better strategies for overcoming the distrust of African-American parents to help achieve adequate participation of African-American children in clinical research."

As compared with white parents, African-American parents:

  • More often reported distrust of medical research, when questions assessing trust were combined and analyzed (67 percent vs. 50 percent)
  • More often believed that physicians prescribe medications as a way of experimenting on unknowing patients (40 percent vs. 28 percent)
  • Were more likely to believe that medical research involves too much risk to the participant (46.8 percent vs. 26 percent), that physicians will not make full disclosures regarding their child's participation (24.6 percent vs. 10 percent) and that research participants would be favored and receive better medical care (48.6 percent vs. 28 percent)

Education level also was associated with distrust, with high distrust scores among 74 percent of those with less than a high school education vs. 44 percent of college graduates. However, race remained associated with higher levels of distrust even after the researchers controlled for education, with African-American parents being two times more likely of being distrusting compared with white parents.

"Race matters," Dr. Thomas said. "It is important for the biomedical research community to acknowledge that African-American distrust toward medicine and research is not irrational; on the contrary, it reflects the legitimate discontent of far too many black families who experience racial discrimination when seeking medical care along with the clear and convincing evidence of racial disparities in their health status compared with whites'. The experience of discrimination is not limited to one individual or one generation but is passed on through word of mouth, keeping alive the cultural memory of how medical science was used to justify the racial inferiority of African-Americans."

The authors conclude that the use of culturally appropriate recruitment materials, as well as using research assistants with similar racial and cultural backgrounds as the subject population, can help provide accurate information and quell parental distrust toward clinical research. Additionally, the establishment of community research advisory boards, which provide feedback at all stages of a research study, as has been done in Pittsburgh, is another means to ensure that minority community members participate and disseminate information about studies while protecting the interests of research subjects and potentially reducing distrust.


Contact: Marc Lukasiak
Children's Hospital of Pittsburgh

Related medicine news :

1. Nautica Malibu Triathlon Presented by Toyota Raises $718,000 for Childrens Hospital Los Angeles Pediatric Cancer Research
2. Childrens Hospital Los Angeles Turns Off the Tap With Green Earth Waterless Carwash
3. Siegel+Gale Designs New HOPE Portal for Childrens Hospital Los Angeles
4. Jessica Biel and Make The Difference Network Bring Holiday Cheer to Childrens Hospital Los Angeles
5. National Childrens Study Begins Recruiting
6. New research explores newborn in-hospital weight loss
7. NYC-area 1st: Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement
8. Norwalk virus: Cruise ship illness challenging and costly to hospitals, too
9. Glades General Hospital First in Palm Beach County to Provide On-Site Electronic Birth Registration
10. Billy Graham Home After Hospitalization:
11. Alvarado Hospital Files Countersuit Against Blue Shield
Post Your Comments:
(Date:11/29/2015)... ... November 29, 2015 , ... Key Housing, a top-rated ... announce their December, 2015, featured apartment community: Epic. In showcasing this featured apartment community ... the tight Bay Area rental market to efficiently find housing suitable to their needs ...
(Date:11/28/2015)... ... ... Safe storage for contraceptive devices may not always be easy to find. ... the other from Bradley Beach, New Jersey, there is an easy solution to the ... replace NuvaRings more often than necessary. As such, it affords peace of mind and ...
(Date:11/28/2015)... (PRWEB) , ... November 28, 2015 , ... Beginning November 30th at 6:00 a.m. EST ... the most savings. , With possible savings of up to 20% off orders $80 or ... homepage of the website every few hours. , As a competitive e-commerce website for skin ...
(Date:11/27/2015)... ... 28, 2015 , ... There is only one major question facing all law ... , This question has not been an easy question to answer. Especially when the ... the younger workforce don’t share the same discipline around working long hours. , ...
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article ... of Toronto and the University of British Columbia suggested that laws requiring bicyclists to ... article explains that part of the reason for the controversial conclusion is that, while ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Nederland, November 26, 2015 ... Een nieuwe aanpak combineert immunotherapie met Bremachlorin-photodynamische ... ) --> ...      (Photo: ) ... Universitair Medisch Centrum (LUMC) blijkt ...
(Date:11/26/2015)... -- 3D bioprinting market is expected to ... report by Grand View Research Inc. Rising prevalence of chronic ... transplantation is expected to boost the market growth, as 3D ... --> 3D bioprinting market is expected to ... report by Grand View Research Inc. Rising prevalence of chronic ...
(Date:11/26/2015)... DUBLIN , November 26, 2015 ... has announced the addition of the  ... in the Global Cell Surface Testing ... Opportunities" report to their offering.  ... the addition of the  "2016 Future ...
Breaking Medicine Technology: