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Children's Hospital of Philadelphia reports on 100 recent fetal surgeries for spina bifida
Date:8/26/2014

cts the flow of cerebrospinal fluid, leading to a progressive hydrocephalus. The authors added that follow-up imaging at age 12 months will be needed to confirm that these very favorable changes persist. In the MOMS trial, 36 percent of the fetal surgery group had no hindbrain herniation at 12 months.

In addition, when compared to prenatal ultrasound evaluations of the anatomic level of the myelomeningocele, 55 percent of the newborns in the study had improved functional motor level, but the authors added that follow-up research will be needed to determine if this benefit persists in longer-term outcome studies.

"Establishing fetal surgery for spina bifida as a standard of care option was one of the most exciting developments in the history of the treatment for birth defects, and one that our CHOP team has spent years helping to pioneer," said N. Scott Adzick, M.D., Surgeon-in-Chief at CHOP and Director of the Center for Fetal Diagnosis and Treatment. Adzick was the lead author of the MOMS trial paper published in the NEJM in 2011. "However, the increased patient acceptance of this procedure, and an increase in centers performing it, underscore the importance of continued collaboration among all centers performing prenatal repair to track long-term results and continue to optimize patient safety and outcomes."


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Contact: Ashley Moore
moorea1@email.chop.edu
267-426-6071
Children's Hospital of Philadelphia
Source:Eurekalert

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