Navigation Links
Children's Hospital Contributes Genotype Data to Enhance Autism Research Worldwide
Date:4/7/2008

PHILADELPHIA, April 7, 2008 /PRNewswire-USNewswire/ -- The Children's Hospital of Philadelphia has contributed a large genotype dataset to the Autism Genetic Resource Exchange (AGRE), a scientific program of the organization Autism Speaks, dedicated to advancing genetic research in autism. This large genetic dataset will now be broadly accessible to autism researchers worldwide.

The Center for Applied Genomics at Children's Hospital employs highly automated microarray technology to perform high-speed genome analysis. The center's HumanHap550 system, manufactured by Illumina, Inc., analyzed 4,500 DNA blood samples gathered by AGRE and generated genotypes -- a compilation of 550,000 genetic markers for each person. Children's Hospital then contributed the genotyped data to AGRE.

By studying patterns of variation in those genotypes, researchers using the AGRE resources will be able to discover and investigate multiple genes that may contribute to autism. Previous family studies have strongly suggested a genetic contribution to autistic spectrum disorders (ASDs). The 4,500 individuals who provided blood samples for the genomic analysis represent approximately 900 families, including 1,250 children with ASDs, their parents and their unaffected siblings.

"We are extremely pleased to provide these genotypes to the public domain," said Hakon Hakonarson, M.D., Ph.D., director of the Center for Applied Genomics at Children's Hospital. "Scientific work using AGRE's data repository will complement our own comprehensive research and clinical programs in autism at Children's Hospital, aimed at finding the causes and cure for this devastating disease." Maja Bucan, Ph.D., professor of Genetics at the University of Pennsylvania, a collaborator on the project and a long-time member of the AGRE steering committee, predicts that "the high-density genotype data on the AGRE families will provide novel insight into a genomic landscape of autism and other
'/>"/>

SOURCE The Children's Hospital of Philadelphia
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Siegel+Gale Designs New HOPE Portal for Childrens Hospital Los Angeles
2. Childrens Hospital Los Angeles Turns Off the Tap With Green Earth Waterless Carwash
3. Nautica Malibu Triathlon Presented by Toyota Raises $718,000 for Childrens Hospital Los Angeles Pediatric Cancer Research
4. Analysis Highlights Economic Contribution of Hospitals to Communities
5. Preliminary Data From Pitt County Memorial Hospital Study Show Benefit of Active Surveillance on Reducing MRSA VAP Rates in Surgical ICU
6. State Report Ranks LIJ as New Yorks Best Hospital for Angioplasty Survival
7. IPC The Hospitalist Company Added to Russell 2000 Index
8. Sen. Kennedy to Speak at Philadelphia Hospital Workers Union
9. Hospital Clinic awarded by CEREBRA Foundation for its excellence in early diagnosis of brain damage
10. Childrens Hospital of Pittsburgh of UPMC Involved in Projects To Develop Nations First Heart Assist Devices for Young Children
11. NCQA Awards Quality Plus Distinction to Blue Cross and Blue Shield of Minnesota for Physician and Hospital Quality Measures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... The Case Management Society of America has ... Lifetime Achievement Award, to Anne Llewellyn RN-BC, MS, BHSA, ... at the association’s 25th Annual Conference and Expo at ... CMSA Board of Directors awards the Lifetime Achievement Award ... contribution to practice of case management and in support ...
(Date:5/27/2015)... (PRWEB) May 27, 2015 The ... provides comprehensive information on the therapeutic development for ... has an orgasm sooner during intercourse. Premature ejaculation ... strengthens R&D pipelines by identifying new targets and ... report on H1 2015 pipeline review of Premature ...
(Date:5/27/2015)... May 27, 2015 Get Tested ... to ending the spread of HIV, will recognize its ... 1st Annual YesGTCV Social Ambassador Awards, to be held ... p.m. PST. , A first for public health campaigns, ... Valley’s most active online influencers for breaking down stigma, ...
(Date:5/27/2015)... Pistol proudly welcomes two new dealers from the wheelchair ... Store of Lakeland, Florida, is a family-owned business with ... have a team of trained professionals who can help ... or car. Additionally, they provide a variety of mobility ... scooters, and manual wheelchairs. , Located in Sarasota, Florida, ...
(Date:5/27/2015)... 2015 HomeTown Health, along with other ... Georgia cities on May 13 & 14. In each ... to meet with the group of representatives and receive ... office staff attended. , Referred to as the ... bring together Health Information Technology and ICD-10 resources with ...
Breaking Medicine News(10 mins):Health News:CMSA to Present Prestigious Lifetime Achievement Award to Anne Llewellyn RN-BC, MS, BHSA, CCM, CRRN 2Health News:Premature Ejaculation Therapeutic Development and Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 2Health News:Premature Ejaculation Therapeutic Development and Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 3Health News:Premature Ejaculation Therapeutic Development and Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 4Health News:Regional Public Health Campaign to Host 1st Annual YesGTCV Social Ambassador Awards 2Health News:Regional Public Health Campaign to Host 1st Annual YesGTCV Social Ambassador Awards 3Health News:Net Pistol Continues Success Serving Mobility Dealers 2Health News:HomeTown Health Leads Rural Physician Bus Tour; Brings Resources and Education to North Georgia 2Health News:HomeTown Health Leads Rural Physician Bus Tour; Brings Resources and Education to North Georgia 3
... for some patients, study says , WEDNESDAY, June 10 ... gene may show marked resistance to an important chemotherapy ... , Scientists at the U.S. National Cancer Institute (NCI) ... how a patient responds to cyclophosphamide, an agent used ...
... - Four suspects often found at the scene of the crime ... cancer in mice that are resistant to the disease, a team ... Cancer Center reports in the June edition of Cancer Cell ... coincidence the three protein receptors and the enzyme that makes them ...
... family members is warranted: report , WEDNESDAY, June 10 ... can suffer too. , A new report from the ... for health and social service professionals to pay greater ... children. , Rather than treating only the depressed adult, ...
... Medical Services Will Host Free Health and Dental Screenings June ... , PITTSBURGH, June 10 As Pennsylvania and ... many individuals have subsequently faced job loss or the loss ... will help those in need by hosting a day of ...
... China and ROCKVILLE, Md., June 10 /PRNewswire-Asia/ -- Synutra,International, ... infant formula,company in China, and a producer, marketer and ... report results for the fourth quarter,and fiscal year ended ... Form 10-K,with the US Securities and Exchange Commission on ...
... healthier lifestyle, offers chance to win a Whirlpool(R) LATITUDE(TM) ... first step in maintaining a healthy lifestyle starts in ... refrigerator is filled with tempting, empty-calorie foods. The ... Brand Cottage Cheese encourages Americans to freshen up their ...
Cached Medicine News:Health News:Researchers identify four new targets for breast cancer 2Health News:If Mom or Dad Is Depressed, Kids Need Help Too 2Health News:If Mom or Dad Is Depressed, Kids Need Help Too 3Health News:Highmark to Sponsor Partners for a Healthy Community Event in Uniontown 2Health News:Highmark to Sponsor Partners for a Healthy Community Event in Uniontown 3Health News:Synutra International, Inc. Sets the Date for its Fourth Quarter and Fiscal Year Earnings Announcement 2Health News:Daisy Brand(R) Cottage Cheese Invites Americans to Freshen Up Your Fridge 2Health News:Daisy Brand(R) Cottage Cheese Invites Americans to Freshen Up Your Fridge 3
(Date:5/26/2015)... May 26, 2015  AbbVie (NYSE: ABBV ... GIFT-I study of its investigational, all-oral, interferon (IFN)- ... ombitasvir/paritaprevir/ritonavir at the Annual Meeting of the Japan ... . 1 GIFT-I evaluated genotype 1b ... patients, with and without cirrhosis, who were either ...
(Date:5/26/2015)... BRAINTREE, Mass. , May 26, 2015  Haemonetics ... Gerry Gould , Vice President, Investor Relations, will present ... Boston on June 4 th , ... public may access Mr. Gould,s presentation live via webcast ... Haemonetics (NYSE: HAE ) is a global ...
(Date:5/26/2015)... , May 26, 2015  XRpro Sciences, Inc., a ... services which features high throughput transporter and ion channel assays ... present at the 2015 Marcum MicroCap Conference on ... at the Grand Hyatt Hotel. The ... Timothy Tyson , Chairman is scheduled to begin at 1:30 ...
Breaking Medicine Technology:AbbVie Presents New Data for its Investigational Hepatitis C Treatment in Japanese Patients With and Without Cirrhosis 2AbbVie Presents New Data for its Investigational Hepatitis C Treatment in Japanese Patients With and Without Cirrhosis 3AbbVie Presents New Data for its Investigational Hepatitis C Treatment in Japanese Patients With and Without Cirrhosis 4AbbVie Presents New Data for its Investigational Hepatitis C Treatment in Japanese Patients With and Without Cirrhosis 5AbbVie Presents New Data for its Investigational Hepatitis C Treatment in Japanese Patients With and Without Cirrhosis 6XRpro Sciences, Inc. To Present at 2015 Marcum MicroCap Conference 2
... human-animal hybrids to generate stem cells WORCESTER, Mass., ... Sheets: ACTC) and its collaborators reported today that human ... adult human cells. The research, which appears online ahead ... Cells (Editor-in-Chief: Sir Ian Wilmut; published by Mary ...
... Robert C. Gallo Foundation for AIDS and Virus ... as director of international relations. The foundation ... internationally known for expertise in HIV prevention, treatment ... producing groundbreaking HIV research."It is an honor to ...
Cached Medicine Technology:Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs 2Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs 3Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs 4Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs 5Franco Nuschese Tapped by Robert C. Gallo Foundation for AIDS and Virus Research 2
... (ELISA) serves the quantitative,determination of the Retinol ... In a 1 hour incubation step, the ... an,available excess of polyclonal rabbit antibodies against ... the microtitre plates. After a washing step, ...
... ADVIA Centaur delivers a ... It provides the flexibility to ... system, now and in the ... a comprehensive disease-focused menu of ...
The Elisa test is used for the detection and semi-quantitative determination of IgG, antibodies to myeloperoxidase in human sera as an aid to the diagnosis is of microscopic polyangiitis....
... (P-ANCA) is for the specific detection ... myeloperoxidase as antigen. No false-positive results ... elastase in the antigen preparation. MPO ... indirect immunofluorescence; only about 10% of ...
Medicine Products: