Navigation Links
Children with juvenile arthritis have higher rates of bacterial infection
Date:4/30/2012

Children with juvenile idiopathic arthritis (JIA) have higher rates of hospitalized bacterial infection than children without JIA according to an observational study appearing in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR). The findings show that the risk of infection among JIA patients was significantly increased with use of high-dose glucocorticoids (steroids). Methotrexate (MTX) and tumor necrosis factor alpha (TNF) inhibitors were not found to increase infection risk in this pediatric population.

Arthritis is an inflammation of the joints that causes pain, swelling, stiffness and can lead to disability. JIA refers to chronic arthritis diseases that attack young patients and the ACR estimates close to 300,000 children in the U.S are affected. While immunosuppressant therapies such as steroids, MTX, and TNF inhibitors are used to treat JIA, it is unclear how they impact infection risk.

To compare bacterial infection incidence in children with and without JIA, a research team led by Dr. Timothy Beukelman from the University of Alabama at Birmingham used U.S. Medicaid data from 2000 to 2005. The team identified 8,479 JIA patients with 13,003 person-years of follow-up and a group of 360,489 children with attention-deficit hyperactivity disorder (ADHD) for comparison. Pharmacy claims were used to determine exposure to MTX, TNF inhibitors, and oral steroid medications. Infections were identified using hospital discharge diagnoses.

Researchers determined that 42% of JIA patients used MTX and 17% used TNF inhibitors to manage their disease. JIA patients without current exposure to MTX or TNF inhibitors had an increased rate of bacterial infection compared to patients with ADHD, even after adjusting for steroid use. "Patients with JIA who were not currently treated with MTX or TNF inhibitors had a 2-fold increase in hospitalized bacterial infection rates co
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Bullied Children at Greater Risk for Self-Harm, Study Finds
2. Dietary changes help some children with ADHD
3. Leaders in childrens health to gather in Boston
4. U.S. Children Exposed to Hours of Background TV Daily
5. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
6. BASPCAN - UK-wide increase in number of children
7. Out-of-hand tree nut consumption associated with better diet quality in children and adults
8. Supporting LGB children may influence their long-term health, BU study finds
9. Children Born to Obese Moms May Face Higher Autism Risk: Study
10. In children born with severe heart defect, surgical management has little effect on neuro outcomes
11. IntegraGen launches ARISk test, a genetic screening tool for autism in high-risk children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... Consuming too much salt? Overloaded on fats, ... the labels! , Learn to decipher the valuable information ... health during a "Healthy Eating for You: Label Reading" ... 755 Ohltown Road, Austintown. , Registered dietician and community ... answer questions. , The presentation is free and ...
(Date:7/25/2014)... July 25, 2014 Sport Court® ... the recent Nike National Invitational Tournament (NIT) ... United States Junior National Tournament (USJN) in Washington ... The flooring for these prestigious national tournaments included 44 ... square feet of playing surface at McCormick Place for ...
(Date:7/25/2014)... reported by People Magazine in the article Mike 'The ... (7/15), one of the most popular cast stars from ... public about his personal transformation. Now, two years later since ... on with his life was a challenge. He was previously ... and even spent some time in rehab. He took the ...
(Date:7/25/2014)... 25, 2014 (HealthDay News) -- The human brain can ... dehydration, a new study finds. Although dehydration ... England have found that the brain compensates by increasing ... "This research has helped us understand a lot ... exercise in extreme conditions," study first author Steven Trangmar, ...
(Date:7/25/2014)... 25, 2014 Art of Facial Surgery has ... those in Toronto who are looking for minor touch-ups to ... done by the American Academy of Facial Plastic and Reconstructive ... in facial plastic surgery showed a surprising increase between 2012 ... percent, while hair transplants increased by 7 percent and eyelid ...
Breaking Medicine News(10 mins):Health News:Learn to Decipher Food Labels at Humility House 2Health News:Sport Court Provides All Sports Flooring for Basketball Events in Chicago and Washington D.C. 2Health News:'The Situation' Celebrates 8 Months of Sobriety 2Health News:'The Situation' Celebrates 8 Months of Sobriety 3Health News:Human Brain Has Coping Mechanism for Dehydration 2Health News:Art of Facial Surgery Responds to Demand for Facial Plastic Surgery Increase Due to the Popularity of Selfies 2Health News:Art of Facial Surgery Responds to Demand for Facial Plastic Surgery Increase Due to the Popularity of Selfies 3
... 10 The Mobile Massage Team ( www.mobilemassageteam.com ), ... corporate wellness programs, promotional events, and special affairs, today ... Buy Lehigh Valley 2009 Trade Fair ( http://www.lehighvalleychamber.org ) ... 2009, from 12:00 noon - 6:00 pm. Team ...
... 10 Availity, LLC, the industry,s premier ... of Russ Thomas to President and Chief ... playing a major role in health care ... platform to advance health quality and efficiency," ...
... Recovery and Relief Initiative to Help Pennsylvania FamiliesHARRISBURG, ... Web site demonstrated in Harrisburg today will help ... than 300 of the most widely-used prescription medications.The ... by Governor Edward G. Rendell as one of ...
... National Race Provides $3.7 Million Impact on D.C. Breast HealthWASHINGTON, ... and the leaders of Susan G. Komen for the Cure(R) ... United States, at the Italian Embassy to officially kick off ... Race for the Cure(R), which will be held on the ...
... NEW YORK, March 10 /PRNewswire-Asia-FirstCall/ -- Biostar Pharmaceuticals,Inc. ... has acquired 8.6 acres,of land located in Xi,an, ... Yang, China. The property cost was approximately ... the construction of a 6,000,square meter pharmaceutical raw ...
... MIAMI, March 10 Karen Peterson has been ... VITAS Innovative Hospice Care(R), one of the nation,s ... position, Peterson will have oversight for the interdisciplinary ... programs located throughout the country.Peterson most recently was ...
Cached Medicine News:Health News:Availity Promotes Russ Thomas to President and Chief Operating Officer 2Health News:New Web Site Will Help Consumers Find Lowest Local Prices for Prescription Drugs 2Health News:D.C. Mayor Fenty, Italian Ambassador Help Announce First-Ever Susan G. Komen Global Race for the Cure(R) 2Health News:D.C. Mayor Fenty, Italian Ambassador Help Announce First-Ever Susan G. Komen Global Race for the Cure(R) 3Health News:D.C. Mayor Fenty, Italian Ambassador Help Announce First-Ever Susan G. Komen Global Race for the Cure(R) 4Health News:Biostar Pharmaceuticals, Inc. Completes 8.6-Acre Land Purchase to House New Raw Materials Processing Plant 2Health News:Biostar Pharmaceuticals, Inc. Completes 8.6-Acre Land Purchase to House New Raw Materials Processing Plant 3Health News:Biostar Pharmaceuticals, Inc. Completes 8.6-Acre Land Purchase to House New Raw Materials Processing Plant 4Health News:VITAS Innovative Hospice Care(R) Names Karen Peterson Vice President and Chief Nursing Officer 2
(Date:7/25/2014)... N.C. , July 25, 2014  Corporate libraries ... including understanding new advancements in technology and how to ... this, libraries in the pharmaceutical and medical device industries ... of the information and services they provide. ... Practices, LLC there are many forces of change that ...
(Date:7/25/2014)... HILL, N.C. , July 25, 2014  In ... area is costly and challenging - as is managing ... Is it possible - or even ... together? If so, where can you combine resources and ... separated? These are just a few ...
(Date:7/25/2014)... July 25, 2014 /PRNewswire-iReach/ -- "Australia Capsule Endoscopy Systems ... the Australia Capsule Endoscopy Systems market. The report provides ... and average prices (in US dollars) within market segments: ... , Capsule Endoscopes , Capsule Endoscopy Data ... The report also provides company shares and distribution shares ...
Breaking Medicine Technology:Forces of Change Reshaping Corporate Libraries & Information Services 2Using Promotional Efficiency to Support Multiple Products and Indications in the Pharmaceutical Marketplace 2Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 2Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 3Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 4Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 5
... SPRING, Md., Feb. 7, 2011 Today the U.S. Food ... implants to conduct postmarket surveillance studies to determine the length ... to pain or other reasons. (Logo: ... (mandible) to the temporal bone in the skull. A person ...
... Abbott (NYSE: ABT ) announced today that ... designed to detect and distinguish 17 different biothreat pathogens. ... dangerous microorganisms that could pose serious threats to human ... public health officials concerned with bioterrorism and emerging infectious ...
Cached Medicine Technology:FDA Orders Postmarket Surveillance of Certain TMJ Implants 2FDA Orders Postmarket Surveillance of Certain TMJ Implants 3Abbott Introduces Biothreat Assay for PLEX-ID™ System 2Abbott Introduces Biothreat Assay for PLEX-ID™ System 3
... C-18 is made of Kydex ... Front and back sections are ... openings to facilitate air circulation ... lightweight and washable. Model C-18 ...
... ensures comfort and immobilization with ... frame and occipital component. Two-piece ... and easy application. Large trachea ... added comfort, removable, flannel-covered, open-cell ...
Exo-Deluxe Overhead Traction for hospital or home care. Twice the clearance of other units between the patient and supporting wall. 2" nylon pulleys with polypropylene cord, head halter, spreader bar...
... Padding&trade is perfect for use for lightweight ... materials or used to line braces, prosthetics, ... against shock and vibration and conforms to ... and chaffing. It is a 2mm thick ...
Medicine Products: