Navigation Links
Children with hypertension have trouble with thinking, memory

Children with high blood pressure are not as good at complicated, goal-directed tasks, have more working memory problems and are not as adept at planning as their peers without hypertension, according to recent research. If they are both hypertensive and obese, they are also more likely to have anxiety and depression.

Considering the demands on a child's brain both in continued development and in education and the fact that up to 10 percent of the increasing population of obese children have hypertension, these novel findings could give physicians and parents more impetus to diagnose and treat high blood pressure in children.

"These results were very surprising to me, despite similar findings in adults," said Marc Lande, M.D., a pediatric nephrologist at the University of Rochester Medical Center and author of the paper published in the Journal of Pediatrics this month. "Adults with hypertension often have other problems that might affect cognition such as chronic disease, smoking or alcohol use. However, children with hypertension usually do not have these comorbidities."

In adults, high blood pressure can lead to stroke, heart disease, heart attack, heart failure and kidney failure. Lande postulates that the cognitive changes demonstrated in this study may represent very early manifestations of hypertensive damage to the brain, which may long precede more overt damage such as stroke.

In addition, more than half the children with both hypertension and obesity demonstrated clinically significant anxiety and depression. Lande said he was initially looking at anxiety and depression only to rule out its interplay with executive function, which is a collection of cognitive abilities that help plan for and respond to complex situations; he did not expect to tease out this new finding.

"Children with only obesity or only hypertension did not have the anxiety and depression that children with both obesity and hypertension did," Lande said. "With further study, screening for anxiety and depression could end up being routine when an obese child is diagnosed with hypertension."

Lande said preliminary results suggest that treatment of hypertension in children may improve their cognitive executive functions, indicating that the changes in cognition associated with hypertension may be reversible with treatment to normalize the blood pressure. .

Lande was inspired to conduct the study after finding a correlation between high blood pressure and lower scores on neurocognitive tests in a nationally representative dataset, NHANES III, the National Health and Nutrition Examination Survey conducted from 1988 to 1994. To dig deeper, Lande enrolled 32 newly diagnosed hypertensive children and adolescents (10 to 18 years old) from the Pediatric Hypertension Clinic at the University's Golisano Children's Hospital. Children who didn't have sustained hypertension or had previous medical issues that affected learning or sleeping were excluded. Thirty-two children with normal blood pressure were recruited from the hospital's pediatric practice and other area pediatric practices and were matched with the hypertensive children by age, weight, sex, race IQ and socioeconomic level.

The parents of both sets of 32 children answered a series of surveys to determine their children's executive function. (Testing the children through parental assessments can be a more valid test because these assessments evaluate the child's abilities in real-life situations better than directly testing a child, one-on-one in a lab setting) Although the hypertensive group did not perform poorly enough to require clinical intervention, the results were significantly different than the group without hypertension.

"We don't know the long-term implications of these subtle changes, but the potential for these differences in cognitive function to affect children is certainly concerning enough to warrant further study," Lande said.


Contact: Heather Hare
University of Rochester Medical Center

Related medicine news :

1. Children of depressed moms do better when dad is involved, SLU researcher finds
2. High pollution linked to poor lung function growth in children in Mexico City
3. NYC-area 1st: Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement
4. Obese Children Miss More School Days
5. Ultra-Runner to Run 63 Marathons in 63 Days for Children with Incurable Disease
6. Psoriasis Cure Now offers Back to School Resources for Parents of Children with Psoriasis
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Practice-based intervention has sustained benefits for children and families
10. 1.5 million children could be saved
11. Annual flu shot cuts need for doctors visits, hospitalization among children
Post Your Comments:
(Date:11/25/2015)... , ... November 25, 2015 , ... Dental professionals who ... Cleveland, OH , are invited to attend Dr. Mark Iacobelli’s Advanced Implant Mentoring (AIM) ... in Cleveland, OH. , As the co-founders of Advanced Implant Mentoring (AIM), Dr. ...
(Date:11/25/2015)... IL (PRWEB) , ... November 25, 2015 , ... The ... announce a recent successful appellate decision obtained by Attorneys Francisco J. Botto and Alex ... Adcock v. Illinois Workers’ Compensation Comm’n, 2015 IL App (2d) 130884WC. , According to ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... ... a double board certified facial plastic surgeon specializing in both surgical and non-surgical ... of The Skin Spa at Hobgood Facial Plastic Surgery. , Highly trained ...
(Date:11/25/2015)... ... November 25, 2015 , ... In an ongoing Clinical Study ... (RMC) in Chicago, IL, UV Angel is evaluating the efficacy of its product and ... care units (totaling 30 beds) from May 2014 through October 2015 at a 360-bed, ...
(Date:11/25/2015)... Missouri (PRWEB) , ... November 25, 2015 , ... ... HEAL, will provide scholarships for people struggling with eating disorders as a result ... from the second annual event, held at Fox Run Golf Club in Eureka, ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... SAN FRANCISCO , November 26, 2015 ... 1.82 billion by 2022, according to a new report by ... as Chronic Kidney Disease (CKD) which demands kidney transplantation is ... convenient and cost effective substitute for organ transplantation. --> ... 1.82 billion by 2022, according to a new report by ...
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Surface Testing Market: Supplier Shares, Competitive ... offering.  --> ) ... "2016 Future Horizons and Growth Strategies ...
(Date:11/26/2015)... , Nov. 26, 2015 Research and Markets ... "Advanced Wound Care Market by Type (Dressings, Therapy ... User (In-Patient Facility, Out-Patient Facility), and Geography - Global ... --> --> The ... definition and forecast of the global advanced wound care ...
Breaking Medicine Technology: