Navigation Links
Children with hypertension have trouble with thinking, memory
Date:2/24/2009

Children with high blood pressure are not as good at complicated, goal-directed tasks, have more working memory problems and are not as adept at planning as their peers without hypertension, according to recent research. If they are both hypertensive and obese, they are also more likely to have anxiety and depression.

Considering the demands on a child's brain both in continued development and in education and the fact that up to 10 percent of the increasing population of obese children have hypertension, these novel findings could give physicians and parents more impetus to diagnose and treat high blood pressure in children.

"These results were very surprising to me, despite similar findings in adults," said Marc Lande, M.D., a pediatric nephrologist at the University of Rochester Medical Center and author of the paper published in the Journal of Pediatrics this month. "Adults with hypertension often have other problems that might affect cognition such as chronic disease, smoking or alcohol use. However, children with hypertension usually do not have these comorbidities."

In adults, high blood pressure can lead to stroke, heart disease, heart attack, heart failure and kidney failure. Lande postulates that the cognitive changes demonstrated in this study may represent very early manifestations of hypertensive damage to the brain, which may long precede more overt damage such as stroke.

In addition, more than half the children with both hypertension and obesity demonstrated clinically significant anxiety and depression. Lande said he was initially looking at anxiety and depression only to rule out its interplay with executive function, which is a collection of cognitive abilities that help plan for and respond to complex situations; he did not expect to tease out this new finding.

"Children with only obesity or only hypertension did not have the anxiety and depression that children with both obesity and hypertension did," Lande said. "With further study, screening for anxiety and depression could end up being routine when an obese child is diagnosed with hypertension."

Lande said preliminary results suggest that treatment of hypertension in children may improve their cognitive executive functions, indicating that the changes in cognition associated with hypertension may be reversible with treatment to normalize the blood pressure. .

Lande was inspired to conduct the study after finding a correlation between high blood pressure and lower scores on neurocognitive tests in a nationally representative dataset, NHANES III, the National Health and Nutrition Examination Survey conducted from 1988 to 1994. To dig deeper, Lande enrolled 32 newly diagnosed hypertensive children and adolescents (10 to 18 years old) from the Pediatric Hypertension Clinic at the University's Golisano Children's Hospital. Children who didn't have sustained hypertension or had previous medical issues that affected learning or sleeping were excluded. Thirty-two children with normal blood pressure were recruited from the hospital's pediatric practice and other area pediatric practices and were matched with the hypertensive children by age, weight, sex, race IQ and socioeconomic level.

The parents of both sets of 32 children answered a series of surveys to determine their children's executive function. (Testing the children through parental assessments can be a more valid test because these assessments evaluate the child's abilities in real-life situations better than directly testing a child, one-on-one in a lab setting) Although the hypertensive group did not perform poorly enough to require clinical intervention, the results were significantly different than the group without hypertension.

"We don't know the long-term implications of these subtle changes, but the potential for these differences in cognitive function to affect children is certainly concerning enough to warrant further study," Lande said.


'/>"/>

Contact: Heather Hare
heather_hare@urmc.rochester.edu
585-273-2840
University of Rochester Medical Center
Source:Eurekalert

Related medicine news :

1. Children of depressed moms do better when dad is involved, SLU researcher finds
2. High pollution linked to poor lung function growth in children in Mexico City
3. NYC-area 1st: Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement
4. Obese Children Miss More School Days
5. Ultra-Runner to Run 63 Marathons in 63 Days for Children with Incurable Disease
6. Psoriasis Cure Now offers Back to School Resources for Parents of Children with Psoriasis
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Practice-based intervention has sustained benefits for children and families
10. 1.5 million children could be saved
11. Annual flu shot cuts need for doctors visits, hospitalization among children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... ... May 02, 2016 , ... One of Hollywood’s best ... Cosmetic Dermatology Surgery & Laser Center, in Milford, Penn. “Patients with busy lives want ... unwanted fat treated and go home or back to work without having to wear ...
(Date:5/1/2016)... ... May 02, 2016 , ... Avid ... Jimi Hendrix Merriweather Post Pavilion in Columbia, Maryland concert posters. Dail Beeghley hit ... concert was held on August 16. According to Hawley, “The Pavilion was built ...
(Date:5/1/2016)... ... May 01, 2016 , ... Good Circle Insurance Agency of ... chiropractic help. The agency offers a verity of health, life and injury policies and ... Chris Nelson at the firm, “Many insurance plans don’t cover chiropractic care, so we ...
(Date:4/30/2016)... ... 2016 , ... Saturday, April 30, marks World Veterinary Day, ... health. The World Veterinary Association (WVA) and the World Organization for Animal Health ... with a One Health focus, which emphasizes how veterinarians pursue continuing education opportunities ...
(Date:4/29/2016)... ... 30, 2016 , ... World Patent Marketing , a ... an automotive invention that improves the storage features of a pick up truck. ... Scott Cooper, CEO and Creative Director of World Patent Marketing. "Over the next ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)...  Marking its one year anniversary since launching ... risk test, Color Genomics announced a ... impact the most common hereditary cancers affecting both ... analyzes hereditary cancer risks for breast, colorectal, melanoma, ... Color Test is physician ordered and includes genetic ...
(Date:4/28/2016)... YORK , April 28, 2016 ... online consumer insights on healthcare, announced today that it ... their report Cool Vendor in Life Sciences, 2016, ... April 15, 2016.  The report focuses on life-science- oriented ... gain insight from patients and doctors, confirm medication ingestion, ...
(Date:4/28/2016)... Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ) ( ... of oral drug delivery systems, announced today that the Company ... Joseph Gunnar & Co. LLC, taking place on ... Nadav Kidron , CEO of Oramed, will present a ...   PIONEERS 2016, presented by Joseph Gunnar ...
Breaking Medicine Technology: