Navigation Links
Children with egg allergies can safely receive flu vaccine, U-M study says
Date:1/22/2013

Ann Arbor, Mich. Egg allergic children, including those with a history of anaphylaxis to egg, can safely receive a single dose of the seasonal influenza vaccine, according to a new study from the University of Michigan.

Historically, the CDC recommended that the seasonal influenza vaccine not be administered to egg allergic children. Recent research conducted at the University of Michigan, and elsewhere, helped modify this recommendation in 2011 so that caution was warranted for only those with severe egg allergy.

The new study, published in the Annals of Allergy, Asthma and Immunology, is good news for children who've had severe egg allergies, given the prevalence of the flu this season. In the study, none of the children with severe egg allergies developed an allergic reaction after receiving the vaccine, says Matthew Greenhawt, M.D., M.B.A., MSc, lead author of the study and assistant professor of allergy and immunology at the University of Michigan's C.S. Mott Children's Hospital.

"The flu vaccine is grown in embryonated chicken eggs and contains residual amounts of ovalbumin, a major egg allergen. This has historically raised concern about the safety of the vaccine in children with egg allergies," says Greenhawt.

"But this study shows these children, all of whom either had anaphylaxis or a severe allergic reaction from egg, can tolerate the vaccine. That's important because we know it's crucial that children get a vaccine to avoid the flu, especially this year as we've seen such an increase in cases and severity. The benefits outweigh the risks."

Influenza A is responsible for 21,156 annual hospitalizations of children younger than five years. The CDC reports that influenza activity right now is high and widespread across the nation. Thirty states and New York City were reporting high activity during the week of Jan. 6. As of Jan. 12, the total number of influenza-associated pediatric deaths was 29 for 2012-13. As many as one-third of children with a food allergy have asthma, and this group is particularly susceptible to influenza.

The American College of Allergy, Asthma and Immunology this month announced that administration of the flu vaccine is safe even in children with a history of a severe allergic reaction to eggs. In its recommendation, the College cited the U-M study.

Egg allergy is one of the most common food allergies in children, but by age 16 about 70 percent outgrow the allergy.

The study showed that a single dose is safe, Greenhawt adds, making it unnecessary to administer the dose in two steps, one of the techniques used in the past to minimize the risk of allergic reactions. He adds that skin testing to the vaccine, another technique used in the past to minimize this risk, is also unnecessary, as was proven in a past U of M study in 2009. Such precautions may have served as barriers to vaccination in the past.

Greenhawt says the only precaution needed is that egg-allergic children should be observed for 30 minutes after vaccination in any medical setting, including primary care providers' offices, where an allergic reaction could be recognized and treated should it occur.

"Because of the prevalence of egg allergy in children is approximately 2%, we know there are a significant number of children who don't get the flu vaccine. This study can put parents' fears to rest and hopefully help more kids avoid the flu," he says.


'/>"/>

Contact: Mary F. Masson
mfmasson@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related medicine news :

1. More U.S. Children Diagnosed With ADHD
2. Nearly half of children under 2 years of age receive some vaccinations late
3. Longer CPR extends survival in both children and adults
4. Cohen Children’s Medical Center of New York Promotes Brand and Wellness with Community Play Area Sponsorship
5. Local Chiropractor Hosting Free Community Event and Giving an iPad Mini Away to Raise Funds for Nonprofit Children's Center at her Grand Opening
6. Dog Sniffs Out Breast Cancer of Susan Castriota, Author and Illustrator of Anti Bully Children’s Book as Recently Aired on WTAE Pittsburgh
7. Study findings have potential to prevent,reverse disabilities in children born prematurely
8. U-M to develop guide for parents of children with disorders of sex development
9. For Some Children, Autism Symptoms May Fade With Age
10. Cody Lovaas to Play Free Great Kindness Challenge Show at New Children's Museum 1/22
11. AkAsha International Launches Children's Book Series
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... , ... October 12, 2017 , ... ... Hair Restoration, has recently contributed a medical article to the newly revamped ... Dr. Mohebi’s article spotlights the hair transplant procedure known as Follicular Unit ...
(Date:10/12/2017)... ... ... Leading pediatric oncology experts at Children’s National Health System will join ... International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired by Jeffrey Dome, ... at Children’s National, and Stephen P. Hunger, M.D., Chief of the Division of ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... been named one of Michigan’s 2017 Best and Brightest in Wellness® by Best ... in Wellness® awards program on Friday, Oct. 20 from 7:30 a.m. to 2 ...
(Date:10/12/2017)... BALTIMORE (PRWEB) , ... October 12, 2017 , ... ... average of $3,296 in property taxes a year. In some states—like New York, ... higher. , By contrast, many overseas retirement havens have extremely low property-tax rates, ...
(Date:10/12/2017)... ... 2017 , ... Farm Forward joins Bon Appétit ... institutions in announcing the launch of the Leadership Circle , a program ... raised for food. , Founding members of the Leadership Circle also include Airbnb’s ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017 West ... in innovative solutions for injectable drug administration, today announced ... the market opens on Thursday, October 26, 2017, and ... results and business expectations at 9:00 a.m. Eastern Time. ... or 253-336-8738 (International). The conference ID is 94093362. ...
(Date:10/11/2017)...  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today provided ... Piedras, Puerto Rico , where the ... Following a comprehensive onsite ... structural damage, temporary loss of power and minimal water ... manufacturing operations have resumed, and the company expects to ...
(Date:10/5/2017)... ROSEMONT, Ill. , Oct. 5, 2017 /PRNewswire-USNewswire/ ... American Association of Oral and Maxillofacial Surgeons (AAOMS) ... than opioids – to be used as a ... post-surgical pain. ... relationship, the AAOMS White Paper "Opioid Prescribing: Acute ...
Breaking Medicine Technology: