Navigation Links
Children more vulnerable to harmful effects of lead
Date:5/4/2008

CINCINNATI Contrary to prevailing assumptions, children are more vulnerable to the harmful effects of lead exposure at the age of 6 than they are in early childhood, according to a Cincinnati Childrens Hospital Medical Center study to be presented May 4 at the annual meeting of the Pediatric Academic Societies in Honolulu.

Although we typically worry about protecting toddlers from lead exposure, our study shows that parents and pediatricians should be just as, if not more concerned about lead exposure in school-aged children, says Richard Hornung, Dr.P.H., a researcher in the division of general and community pediatrics at Cincinnati Childrens and the studys main author.

The researchers found that blood lead concentrations (BPb) at age 6, compared to those at younger ages, are more strongly associated with IQ and reduced volume of gray matter in the prefrontal cortex of the brain, which is involved in planning, complex thinking and moderating behavior.

Overall, the childrens average BPb levels peaked at 13.9 micrograms of lead per deciliter of blood at age 2, then declined to an average of 7.3 micrograms per deciliter by age 6. For children, however, with the same average blood lead levels through age 6, those who received more of their exposure at age 6 had substantially greater decrements in intellectual ability than those more heavily exposed at age 2.

Lead toxicity is difficult to recognize in a clinical setting, but it can have devastating effects, says Bruce Lanphear, M.D., director of the Cincinnati Childrens Environmental Health Center and the studys senior author. We found that children may be particularly vulnerable to lead exposure just as the child approaches school age, during a period of rapid cognitive development.

Because IQ tests were not administered to children older than 6, it is unknown whether older children are even more vulnerable to environmental lead exposure, according to Dr. Hornung.

Approximately 310,000 U.S. children age 1 to 5 years have blood lead levels greater than 10 micrograms per deciliter, the level at which the Centers for Disease Control and Prevention recommends public health actions be initiated. But research has consistently shown that blood lead levels considerably lower than 10 micrograms per deciliter are associated with adverse effects.

Federal and state regulatory standards have helped to minimize or eliminate the amount of lead in U.S. consumer products and occupational settings, according to the National Institute of Environmental Health Sciences (NIEHS). Today, the most common sources of lead exposure in the United States are lead-based paint in older homes, contaminated soil, household dust, drinking water, lead crystal and lead-glazed pottery.

While extreme lead exposure can cause a variety of neurological disorders, such as lack of muscular coordination, convulsions and coma, lower lead levels have been associated with measurable deficits in childrens mental development and behavioral problems. These include hyperactivity, or ADHD, lowered performance on intelligence tests, and deficits in fine motor function, hand-eye coordination and reaction time. Chronic lead exposure in adults can result in increased blood pressure, decreased fertility, cataracts, nerve disorders, muscle and joint pain as well as problems with memory or concentration.


'/>"/>

Contact: Jim Feuer
jim.feuer@cchmc.org
513-636-4656
Cincinnati Children's Hospital Medical Center
Source:Eurekalert

Related medicine news :

1. Children of depressed moms do better when dad is involved, SLU researcher finds
2. High pollution linked to poor lung function growth in children in Mexico City
3. NYC-area 1st: Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement
4. Obese Children Miss More School Days
5. Ultra-Runner to Run 63 Marathons in 63 Days for Children with Incurable Disease
6. Psoriasis Cure Now offers Back to School Resources for Parents of Children with Psoriasis
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Practice-based intervention has sustained benefits for children and families
10. 1.5 million children could be saved
11. Annual flu shot cuts need for doctors visits, hospitalization among children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson Insurance and ... and financial preparation services, is providing an update on a charitable event that ... City Rescue is a locally recognized nonprofit that provides shelter and care for ...
(Date:10/13/2017)... ... ... While it’s often important to take certain medications during the night, finding them ... a solution. , She developed a prototype for MOTION LIGHT-UP PILL BOX to provide ... need to turn on a light when taking medication during the night, allowing the ...
(Date:10/13/2017)... IL (PRWEB) , ... October 13, 2017 , ... ... which established the certification process to promote standards of excellence for the field ... Symposium, scheduled for March 22 – 25, 2018 in Orlando, Florida at the ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, ... guideline updates for the primary prevention of cardiovascular diseases during the 15th ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , which specializes ... of the facility as part of a disaster drill on October 3rd. , Apple ... Shelton City Emergency Manager, as well as the Connecticut Long Term Care Mutual ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Divoti USA will engrave and process all non-coated stainless ... FDA requirements, which stipulates new criteria regarding medical device manufacture and ... ID jewelry such as Medical ID Bracelets, can rest assured that ... the new FDA requirements . ... Divoti offers this dark mark fiber laser engraving process with ...
(Date:10/11/2017)... PARK, Calif. , Oct. 11, 2017  BioPharmX ... national scientific team that developed an innovative way to ... quantity of the delivery of new drugs. ... 2017 Fall Clinical Dermatology Conference will show how researchers ... General Hospital, Harvard Medical School used a suite of ...
(Date:10/11/2017)... FRISCO, Texas , Oct. 11, 2017 /PRNewswire/ ... healthcare services, has amplified its effort during National ... patients about hereditary cancer risks. ... Journal of Clinical Oncology calculated that more than ... to have inherited mutations in BRCA1 or BRCA2 and ...
Breaking Medicine Technology: