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Children born prematurely face up to a 19 times greater risk of retinal detachment later in life
Date:11/7/2013

potential cofounders.

Those born very prematurely (28 to 31 weeks of gestation) between 1973 and 1986 had a four-fold increased risk and those born very prematurely between 1987 and 2008 had a three-fold greater risk than those born at term. Additionally, the researchers found that moderately preterm birth (32 to 36 weeks of gestation) was not associated with an increased risk of retinal detachment.

"We may just be seeing the tip of the iceberg of late ophthalmic complications after preterm birth," said Anna-Karin Edstedt Bonamy, M.D., Ph.D., pediatrician at Karolinska Institutet in Stockholm and the study's lead researcher. "Not only does the risk of retinal detachment increase with age, but there has also been an increase in survival among people born prematurely since the 1970s. This provides opportunities for future research to address if the increased risk persists among those born prematurely as they age."

Clinical studies and care series indicate that individuals born prematurely may be at lifelong risk for ophthalmologic complications other than ROP. This includes an increased risk of subnormal visual acuity, visual perceptual problems, strabismus, refractive errors (particularly high myopia) and reduced contrast sensitivity and visual fields.

The American Academy of Pediatrics, along with the American Academy of Ophthalmology, American Association for Pediatric Ophthalmology and Strabismus and the American Association of Certified Orthoptists recommend screening for ROP in infants born at less than 30 weeks of gestation or those with a birth weight of less than 1500 grams (or those with a birth weight of less than 2000 grams with an unstable clinical course).

Although follow-up guidelines vary from country to country, the researchers recommend that individuals who have been treated for ROP in the neonatal period should continue follow up on a yearly basis.


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Source:Eurekalert

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