Navigation Links
Children born prematurely face up to a 19 times greater risk of retinal detachment later in life

SAN FRANCISCO Nov. 7, 2013 Children born extremely prematurely have up to a 19 times greater risk of retinal detachment later in life than peers born at term, according to a Swedish study published this month in Ophthalmology, the journal of the American Academy of Ophthalmology. In the first large population-based, long-term investigation of the association between preterm birth and later retinal detachment, the research determined that birth before 32 weeks is associated with increased risks of retinal detachment in childhood, adolescence and young adult life. The study's findings indicate the need for ophthalmologic follow-up in children and adults born extremely and very prematurely. The United States has the sixth largest number of premature births, with more than 500,000 premature babies born each year.

The researchers used Swedish nationwide population registries of more than three million births from 1973 to 2008 to identify subjects born prematurely (at less than 37 weeks of gestation), who were then separated into two groups: those born between 1973 and 1986, at which point a national retinopathy of prematurity (ROP) screening program was established, and those born between 1987 and 2008. ROP is a condition that causes abnormal blood vessels to grow in the retina (back of the eye) and can cause retinal detachment, which is a major cause of childhood blindness globally. A detached retina may lead to vision loss and even blindness unless it is treated with surgery. Although the connection between retinal detachment and preterm births has been noted in smaller studies, this is the first study to analyze a population of this size.

For those born extremely prematurely (less than 28 weeks of gestation) between 1973 and 1986, the researchers found the risk of retinal detachment was 19 times higher than peers born at term. Those born extremely prematurely between 1987 and 2008 had a nine-fold increase in risk after adjustment for potential cofounders.

Those born very prematurely (28 to 31 weeks of gestation) between 1973 and 1986 had a four-fold increased risk and those born very prematurely between 1987 and 2008 had a three-fold greater risk than those born at term. Additionally, the researchers found that moderately preterm birth (32 to 36 weeks of gestation) was not associated with an increased risk of retinal detachment.

"We may just be seeing the tip of the iceberg of late ophthalmic complications after preterm birth," said Anna-Karin Edstedt Bonamy, M.D., Ph.D., pediatrician at Karolinska Institutet in Stockholm and the study's lead researcher. "Not only does the risk of retinal detachment increase with age, but there has also been an increase in survival among people born prematurely since the 1970s. This provides opportunities for future research to address if the increased risk persists among those born prematurely as they age."

Clinical studies and care series indicate that individuals born prematurely may be at lifelong risk for ophthalmologic complications other than ROP. This includes an increased risk of subnormal visual acuity, visual perceptual problems, strabismus, refractive errors (particularly high myopia) and reduced contrast sensitivity and visual fields.

The American Academy of Pediatrics, along with the American Academy of Ophthalmology, American Association for Pediatric Ophthalmology and Strabismus and the American Association of Certified Orthoptists recommend screening for ROP in infants born at less than 30 weeks of gestation or those with a birth weight of less than 1500 grams (or those with a birth weight of less than 2000 grams with an unstable clinical course).

Although follow-up guidelines vary from country to country, the researchers recommend that individuals who have been treated for ROP in the neonatal period should continue follow up on a yearly basis.


Contact: Media Relations
American Academy of Ophthalmology

Related medicine news :

1. Earth Source Organics Boosts Movement to Promote Healthy Eating in Children
2. Families, Businesses & Special Needs Children Rally to Support America's Special Kidz (A.S.K.)'s First Fundraiser
3. New study assesses injuries seen in the emergency department to children of teenage parents
4. NYC Injury Lawyers Block O'Toole & Murphy Hosted Their 2013 Autumn Wine Tasting Event To Benefit St. Jude Children's Research Hospital And It Was A Huge Success
5. Therapist Introduces iPads as Educational Tool for Children with Special Needs
6. SC&H Group Donates 84 Refurbished Laptop Computers to Children’s Guild and Arc Baltimore
7. MomToMom Has Launched a New iPhone App to Help Moms Find Great Deals on Children's Clothing, Toys and Gear, and Provide Them an Easy Way to Earn Extra Money
8. Founders of World of Children Award Recognized as Most Inspiring Power Couple
9. Everspark Interactive Attending Kids II Strong Legs Run to Benefit Children’s Healthcare of Atlanta
10. Children’s Medical Center of Dallas Retains B. E. Smith to Recruit New Senior Director of Accreditation and Policy Management
11. Double-pronged attack could treat common childrens cancer
Post Your Comments:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer ... they remain in the eye of the beholder, according to experts who offered insights ... American Journal of Managed Care. For the full issue, click here . , ...
(Date:6/26/2016)... ... ... a legally blind and certified personal trainer is helping to develop a weight loss fitness ... to fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to a ... new, often overlooked aspect of head lice: the parasite’s ability to live away from a ... occurrence, but a necessary one in the event that lice have simply gotten out of ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... RIDGE, Ill. and INDIANAPOLIS ... of students receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship ... The 2016 scholarship winners, announced today online at ... to let type 1 diabetes stand in the way ... Diabetes has supported the Foundation,s scholarship program since 2012, ...
(Date:6/23/2016)... June 23, 2016  Guerbet announced today that it ... Supplier Horizon Award . One of 12 ... recognized for its support of Premier members through exceptional ... excellence, and commitment to lower costs. ... recognition of our outstanding customer service from Premier," says ...
(Date:6/23/2016)... 2016  Experian Health, the healthcare industry ... patient payment and care experience, today announced ... and services that will enhance the breadth ... These award-winning solutions will enable healthcare professionals ... in an ever-changing environment and redefine front-office ...
Breaking Medicine Technology: