Navigation Links
Children born prematurely are at higher risk of esophageal inflammation, cancer
Date:12/11/2012

Infants that are born preterm or with impaired growth have an increased risk of developing gastroesophageal reflux disease (GERD), possibly leaving them vulnerable to the development of esophageal adenocarcinoma later in life. Gestational age and size at birth affect the risk of an early diagnosis of esophagitis inflammation of the esophagus according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

"Long-term exposure to reflux is a major risk factor for esophageal cancer. Therefore, those exposed to reflux early in life, such as preterm-born infants and children, may face a higher risk of developing esophageal cancer," said Lina Forssell, MD, of the Karolinska Institutet, Stockholm, Sweden and first author of this study. "Having found an increased risk of esophagitis among those born preterm, it is important that we try to quantify their subsequent risk of developing esophageal cancer."

Researchers analyzed data from the Swedish birth register and patient register to identify birth characteristics of individuals with esophagitis from 1973 to 2007. They found that the risk of esophagitis was increased by 170 and 50 percent among individuals born preterm and small for gestational age, respectively. Being small for gestational age at birth was associated with an increased risk of esophagitis in all age groups, whereas short-duration gestation was strongly associated with an increased risk of esophagitis at age 0 to 9 years, moderately associated at ages 10 to 19 years, and not associated at later ages. The overall association between preterm birth and risk of esophagitis was stronger among males than females.

In conclusion:

  • Being born very preterm (≤ 32 complete weeks) seems to increase the risk of esophagitis almost three-fold, independent of age at diagnosis.

  • Being born very preterm also seems to increase the risk of esophagitis diagnosed before the age of 10 almost seven-fold.

  • The effect of preterm birth on the risk of esophagitis is seemingly stronger among males than females.

Among infants, GERD is very common, but usually disappears by the time they turn a year old. However, some children have continuing problems: about 40 to 77 percent of children below the age of 2 with GERD have esophagitis. GERD is also a known risk factor for esophageal cancer.


'/>"/>

Contact: Alissa Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Related medicine news :

1. Device helps children with disabilities access tablets
2. Intensified chemotherapy shows promise for children with very high risk form of leukemia
3. Wayne State researcher finds possible clue to childrens early antisocial behavior
4. Metformin improves blood glucose levels and BMI in very obese children
5. Beverly Hills Dentist Dr. David Frey raises money for the Jerusalem Dental Center for Children
6. Fasting may benefit patients with epilepsy, Johns Hopkins Childrens Center study suggests
7. Atherosclerosis found in HIV children
8. Children with autism arrive at emergency room for psychiatric crisis 9 times more than peers
9. Childrens Seizures Not Always Damaging, Study Finds
10. Familys economic situation influences brain function in children
11. Study finds alarming 15-fold increase in inflatable bouncer-related injuries among children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... are unfamiliar with. The article goes on to state that individuals are now more ... these less common operations such as calf and cheek reduction. The Los Angeles area ...
(Date:6/24/2016)... ... , ... June 19, 2016 is World Sickle Cell Observance Day. In an ... of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a ... Cell Disease (SCD) is a disorder of the red blood cells, which can cause ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... and Scientific Sessions in Dallas that it will receive two significant new grants ... grants came as PHA marked its 25th anniversary by recognizing patients, medical professionals ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all ... brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief ... a minimum wage raise to $12 an hour by 2020 and then adjusting it yearly ... lost value of the minimum wage, assure the wage floor does not erode again, and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Research and Markets has announced the addition of the ... to their offering. ... World Market for Companion Diagnostics covers the world market for ... report includes the following: , World IVD ... (N. America, EU, ROW), 2015-2020 , World IVD Companion ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, a ... invasive and more durable cerebrospinal fluid treatments, today ... The Series-A funding is led by Innova Memphis, ... and other private investors.  Arkis, new financing will ... and the market release of its in-licensed Endexo® ...
(Date:6/23/2016)... 2016 Research and Markets has ... by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), ... Parenteral) - Global Forecast to 2021" report to ... The global pharmaceutical excipients market is projected to reach ... 6.1% in the forecast period 2016 to 2021. ...
Breaking Medicine Technology: