Navigation Links
Children born prematurely are at higher risk of esophageal inflammation, cancer
Date:12/11/2012

Infants that are born preterm or with impaired growth have an increased risk of developing gastroesophageal reflux disease (GERD), possibly leaving them vulnerable to the development of esophageal adenocarcinoma later in life. Gestational age and size at birth affect the risk of an early diagnosis of esophagitis inflammation of the esophagus according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

"Long-term exposure to reflux is a major risk factor for esophageal cancer. Therefore, those exposed to reflux early in life, such as preterm-born infants and children, may face a higher risk of developing esophageal cancer," said Lina Forssell, MD, of the Karolinska Institutet, Stockholm, Sweden and first author of this study. "Having found an increased risk of esophagitis among those born preterm, it is important that we try to quantify their subsequent risk of developing esophageal cancer."

Researchers analyzed data from the Swedish birth register and patient register to identify birth characteristics of individuals with esophagitis from 1973 to 2007. They found that the risk of esophagitis was increased by 170 and 50 percent among individuals born preterm and small for gestational age, respectively. Being small for gestational age at birth was associated with an increased risk of esophagitis in all age groups, whereas short-duration gestation was strongly associated with an increased risk of esophagitis at age 0 to 9 years, moderately associated at ages 10 to 19 years, and not associated at later ages. The overall association between preterm birth and risk of esophagitis was stronger among males than females.

In conclusion:

  • Being born very preterm (≤ 32 complete weeks) seems to increase the risk of esophagitis almost three-fold, independent of age at diagnosis.

  • Being born very preterm also seems to increase the risk of esophagitis diagnosed before the age of 10 almost seven-fold.

  • The effect of preterm birth on the risk of esophagitis is seemingly stronger among males than females.

Among infants, GERD is very common, but usually disappears by the time they turn a year old. However, some children have continuing problems: about 40 to 77 percent of children below the age of 2 with GERD have esophagitis. GERD is also a known risk factor for esophageal cancer.


'/>"/>

Contact: Alissa Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Related medicine news :

1. Device helps children with disabilities access tablets
2. Intensified chemotherapy shows promise for children with very high risk form of leukemia
3. Wayne State researcher finds possible clue to childrens early antisocial behavior
4. Metformin improves blood glucose levels and BMI in very obese children
5. Beverly Hills Dentist Dr. David Frey raises money for the Jerusalem Dental Center for Children
6. Fasting may benefit patients with epilepsy, Johns Hopkins Childrens Center study suggests
7. Atherosclerosis found in HIV children
8. Children with autism arrive at emergency room for psychiatric crisis 9 times more than peers
9. Childrens Seizures Not Always Damaging, Study Finds
10. Familys economic situation influences brain function in children
11. Study finds alarming 15-fold increase in inflatable bouncer-related injuries among children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the Law ... organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps our ... a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... ... 2017 , ... Ellevate Network, the leading network for professional women, brought together ... equality at their inaugural Summit in New York City in June. The event was ... of over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer ... one of the most popular and least understood books in the Holy Scriptures, Revelation. ... descriptions that have baffled scholars for centuries. Many have tossed it off as mere ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... , Oct. 2, 2017 The Rebound mobile ... the struggle to reverse the tide of prescription drug addiction. ... regulating their medicine intake and stepping down their dosage in ... to launch in December 2017; the first 100,000 people to ... more at http://www.rebound-solution.com/ ...
(Date:9/28/2017)... Cohen Veterans Bioscience and Early Signal Foundation ... and home sensors for real-time monitoring of patients with ... nonprofit organization focused on disruptive health solutions for rare ... system to record and integrate behavioral, cognitive, physiological and ... ...
(Date:9/27/2017)... , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading ... announced that its MyDario product is expected to appear on The Dr. ... The Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. Oz Show ... The segment ...
Breaking Medicine Technology: