Navigation Links
Childhood stress such as abuse or emotional neglect can result in structural brain changes
Date:2/25/2010

New research using magnetic resonance imaging (MRI) shows that childhood stress such as abuse or emotional neglect, in particular when combined with genetic factors, can result in structural brain changes, rendering these people more vulnerable to developing depression. The study led by scientists at Trinity College Dublin has just been published in the international scientific journal, Neuropsychopharmacology.

Commenting on the significance of the findings, Trinity's Professor Thomas Frodl at the School of Medicine and Trinity Institute for Neuroscience said: "This improved neurobiological understanding shows how stress and genetic variants interact and affect brain structure and function. In turn it demonstrates how it could affect a person's propensity for depression. These structural alterations of the brain are associated with a higher vulnerability to depression and a more chronic course of the depression might be associated with further structural changes".

"Therefore, early intervention in the case of major depression is necessary to increase the chance of a good disease outcome. Fortunately, depression can be treated very well by psychotherapy and antidepressant medication. Moreover, prevention strategies for childhood neglect and misuse are highly important to increase public health and to avoid in later life for these individuals, the burden of major depression."

The world health organisation (WHO) found that major depression is one of the most important human diseases with a prevalence of about 10% worldwide. Approximately 500,000 people in Ireland have or will develop major depression in their life. The WHO has forecast that major depression will be the second most common cause of disability by 2020. Advances in this area will have a high impact on overall disease costs.

The study was conduceted on a total of 24 patients (aged 18-65 years) being treated as inpatients for major depression. They were investig
'/>"/>

Contact: Caoimhe Ni Lochlainn
communications@tcd.ie
353-896-2310
Trinity College Dublin
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Genetic predisposition increases childhood asthma risk
2. Treating diabetes during pregnancy can break link to childhood obesity
3. Childhood asthma still inappropriately treated in the UK
4. Screening Proposed for Childhood Cholesterol Levels
5. Success of Shape-Up Somerville Childhood Obesity Intervention to be Presented at the Friedman School Symposium at Tufts, October 29-31, 2007 - Boston
6. Success of Shape Up Somerville childhood obesity intervention to be presented
7. Childhood vaccination may protect adult eyes
8. Childhood Obesity Epidemic a Long-Term Challenge
9. New chemotherapy regimen prolongs survival in difficult-to-treat childhood brainstem gliomas
10. Antibiotics Not Always Best Bet for Battling Childhood Ear Infections
11. Childhood TV viewing a risk for behavior problems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... of a gene controlling red blood cell development have ... the globe, according to a new study led by ... of world populations to look for the origin of ... haemoglobin production into adulthood. Fetal haemoglobin is normally found ... blood disorders who are able to keep making it ...
(Date:7/28/2014)... Cancer cells are gluttons. We have long known that ... became clear that some tumor cells are also characterized ... unlikeliness to join in an ordered set. Researchers are ... metastasis. , At EPFL, Etienne Meylan,s research team was ... for sugar and mesenchymal behavior result from the ...
(Date:7/28/2014)... 29, 2014 The “Tissue ... Hybridization, Digital pathology & Workflow, Special Staining), ... Cancer, Non Small Cell Lung Cancer and ... Pharmaceutical companies, Research Laboratories, Contract Research Organizations ... Europe, BRIC, Japan & RoW) - Trends ...
(Date:7/28/2014)... July 28, 2014 A lush green lawn ... during the summer. However, the summer heat, lack of rain, ... become brown, weak and unhealthy. The Grounds Guys recommends these ... Mow a lawn once a week and set the height ... This protects the grass roots from heat and allows roots ...
(Date:7/28/2014)... Sterling Heights, MI (PRWEB) July 28, 2014 ... network UHY, introduces the latest edition of UHY International ... insight, provided by our members, on the most current ... individuals around the world. Issue 29 covers the following ... global growth: Which industry sectors will thrive over the ...
Breaking Medicine News(10 mins):Health News:Study tracks worldwide spread of beneficial blood cell gene variant 2Health News:Study tracks worldwide spread of beneficial blood cell gene variant 3Health News:Cancer: Tumors absorb sugar for mobility 2Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 2Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 3Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 4Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 5Health News:Nurturing Lawns in the Summer Heat: The Grounds Guys® Offers Tips on Caring for Lawns This Summer 2Health News:Uhy International Business Issue 29 Now Available 2Health News:Uhy International Business Issue 29 Now Available 3
... initiative to combat HIV infection among its cadres, the ... in every border outpost along West Bengal's international boundary. ... Project Prahari initiative launched in collaboration with the state ... HIV/AIDS among BSF troopers. ,"We are setting up ...
... Galveston (UTMB) have found a method to detect the proteins ... people. According to their findings, it is now possible to ... causing the disease.// ,The study was reported in ... the study are expected to lead to a much more ...
... doing household activities like cleaning the house and the ... conditions of prehypertension in people. // ,The ... accumulated daily lifestyle physical activity had the effect of ... from hypertensive to prehypertensive and from prehypertensive to normal ...
... Premenstrual syndrome is an endocrine disorder characterized by ... thirst, headache and pelvic congestion. ,For the ... unique progestin and dosing regimen has been found ... (PMDD), the most severe form of premenstrual syndrome. ...
... The immune system has the remarkable ability to discriminate ... functioning of the immune system, the human body would ... leading to death. // ,The immune system ... pathogens and cancer cells, effectively labeling them as "bad" ...
... Ministry of Health is in search of a new cheaper ... Government has reported 200 deaths and 700 patients with infection. ... due to the endemic infection of Encephalitis in Uttar Pradesh. ... 67 patients were admitted in the Government College Hospital in ...
Cached Medicine News:Health News:Free Condom Counters For Border Security Force Cadres 2Health News:They Call It PMS Because Mad Cow Disease Was Already Taken 2Health News:Fighting against disease as easy as eating eggs 2
(Date:7/28/2014)... HOUSTON , July 28, 2014  Houston ... announces that he offers orthodontic treatment with Invisalign. ... area patients can have their teeth straightened without ... same long-term benefits associated with other types of ... enjoy natural looks in addition to better support ...
(Date:7/28/2014)... Fla. , July 28, 2014  TNI ... a biopharmaceutical company focused on the development, marketing ... it has filed definitive proxy materials with the ... 2014 Annual Meeting of Shareholders to be held ... East Standard Time. The record date for determining ...
(Date:7/28/2014)... -- ResMed (NYSE: RMD ), innovatore e ... disturbi respiratori del sonno (SDB) e altre patologie croniche ... contro il produttore Taiwanese di dispositivi medicali, APEX Medical ... indossare in testa, che violano i brevetti, utilizzate con ... della Corte Regionale Distrettuale di Monaco ...
Breaking Medicine Technology:Houston Cosmetic Dentist, Dr. Behzad Nazari, Now Offers Orthodontic Treatment with Invisalign 2TNI BioTech, Inc., Files Definitive Proxy Materials; Mails Letter Urging Shareholders to Vote the Proxy Card 2TNI BioTech, Inc., Files Definitive Proxy Materials; Mails Letter Urging Shareholders to Vote the Proxy Card 3ResMed riceve un'ingiunzione permanente contro APEX in Germania, continua a far valere i propri diritti per i brevetti in Europa 2
... Md., May 24, 2007 /PRNewswire-FirstCall/ -- Iomai,Corporation today ... 1 trial of its patch-based needle-free influenza vaccine,before ... live,webcast will be held at 8:30 a.m. Eastern ... Details , To access the live conference call ...
... Texas--(BUSINESS WIRE)--May 29, 2007 - Introgen,Therapeutics, Inc. ... updated Phase 2 clinical trial results,for its ... upcoming,annual meetings of The American Society of ... Society of Gene Therapy (ASGT) in,Seattle., "We ...
Cached Medicine Technology:Iomai to Announce Results From Phase 1 Influenza Trial and Host,Webcast Tomorrow 2Introgen and Clinical Collaborators to Report New Results with,Advanced-Stage Cancer Therapies at Upcoming Medical Meetings 2Introgen and Clinical Collaborators to Report New Results with,Advanced-Stage Cancer Therapies at Upcoming Medical Meetings 3
The latex free, hydrophilic Self-Cath Plus is designed for single use, intermittent self-catheterization. The unique hydrophilic coating activates immediately upon exposure to water for fast, clean...
... Closed System is a latex-free unisex ... safe, simple catheterization designed to reduce ... It includes a 100% latex-free ... EasyOff tear tab makes it easy ...
... The Self-Cath Closed System is a ... method for safe, simple catheterization designed ... tract infections. It includes a ... The new EasyOff tear tab makes ...
... The Self-Cath family ... offers patients a variety ... self-catheterization. Each catheter ... medical grade PVC and ...
Medicine Products: