Navigation Links
Childhood cancer survivors are at increased risk for ongoing post-therapy GI complications
Date:5/4/2011

ific combinations of chemotherapy, radiation and surgery have dramatically improved survival, these treatment modalities have the potential to cause significant GI complications. For example, abdominal radiation often results in several acute toxicities, including intestinal inflammation and abnormal movement of the intestinal tract. Chemotherapy is associated with many acute GI toxicities, including nausea, vomiting, diarrhea, constipation and increased susceptibility to GI infections. Intra-abdominal surgery and subsequent GI complications are also contributors to GI toxicity of cancer therapy. Long-term GI consequences, however, have not been extensively studied.

In this study, doctors evaluated the incidence of long-term GI outcomes and identified treatment-related risk factors. The goals of this analysis were to describe the incidence of self-reported adverse GI conditions occurring at least five years after diagnosis and to evaluate the effect of different treatment-associated factors on the risk of developing these GI events.

Upper GI, lower GI and liver adverse outcomes were assessed in cases from participants in the Childhood Cancer Survivor Study, a study of 14,358 survivors of childhood cancer (i.e., leukemias, brain tumors, lymphomas, Wilms tumor, neuroblastoma, sarcomas and bone tumors) who were diagnosed between 1970 and 1986 at one of 26 collaborating institutions in the U.S. and Canada; data were compared with those from randomly selected siblings. The median age at cancer diagnosis was 6.8 years, and the median age at outcome assessment was 23.2 years for survivors and 26.6 years for siblings.


'/>"/>

Contact: Alissa J. Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Biological links found between childhood abuse and adolescent depression
2. Childhood music lessons may provide lifelong boost in brain functioning
3. Minority Kids With Heart Defects More Likely to Die in Childhood
4. Quality of parent-toddler relationship could affect risk for childhood obesity
5. Results on national study of parental concerns about childhood vaccines announced
6. Innovative screening method identifies possible new treatment for fatal childhood disease
7. Minorities born with heart defects at higher risk of dying in early childhood than whites
8. Childhood eczema and hay fever leads to adult allergic asthma
9. Fatigue and sleep woes worsen neurocognitive problems in childhood cancer survivors
10. Sleep Problems May Linger After Childhood Cancer
11. Sleep issues contribute to cognitive problems in childhood cancer survivors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... (PRWEB) , ... August 05, 2015 , ... The ... Pain and Obesity ”. , As corresponding author Professor Akiko Okifuji says “Both obesity ... often, although it is not to say that one causes the other. Rather, there ...
(Date:8/4/2015)... ... August 04, 2015 , ... assistPoint Partners, LLC is ... oncology patient assistance programs. Through a secure web portal, assistPoint connects Life Sciences, ... enterprise level, cloud-based application and workflow solution. This provides cancer center patient advocates, ...
(Date:8/4/2015)... FL (PRWEB) , ... August 04, 2015 , ... ... testing organization which provides vascular, electrocardiogram (EKG), echocardiogram, and NCV testing, announced their ... has been successfully identifying previously undiagnosed cardiovascular abnormalities one program at a time. ...
(Date:8/4/2015)... ... August 04, 2015 , ... Bayco Products, Inc. announces a new industrial-grade LED ... on hard hats that have a flip-up face shield. The sleek contours of the ... without having to remove their headlamp when raising or lowering their face shield or ...
(Date:8/4/2015)... ... August 04, 2015 , ... Worldwide ... Power Products is expanding its reach in Texas. Effective July 1st of this ... North Texas generator division. With the North Texas acquisition, Worldwide Power Products ...
Breaking Medicine News(10 mins):Health News:The Association between Chronic Pain and Obesity published by Dove Medical Press 2Health News:assistPoint.com Web Site Launched 2Health News:Colleges and High Schools Across the Country Are Joining the Wimbledon U Team Uncovering Unknown Cardiac Conditions and Promoting Heart Healthy Athletes 2Health News:Colleges and High Schools Across the Country Are Joining the Wimbledon U Team Uncovering Unknown Cardiac Conditions and Promoting Heart Healthy Athletes 3Health News:New Nightstick® NSP-4614B Dual-LightTM Headlamp fits more functionality into more places 2Health News:New Nightstick® NSP-4614B Dual-LightTM Headlamp fits more functionality into more places 3Health News:North Texas Acquisition Press Release 2
... News) -- Simple precautions will help keep you safe and ... for winter or put up holiday decorations, experts say. ... treated in U.S. emergency departments for holiday decorating-related falls, according ... of those injuries were caused by falls from ladders. ...
... find out whether a new drug or treatment makes ... life, according to a commentary published online December 3rd ... . Instead, most trials now are designed to detect ... which may not be clinically meaningful, write Alberto Ocana, ...
... -- New research explains why immune function actually improves in a ... cases, the virus has mutations that protect it against some HIV ... the researchers at the Mayo Clinic in Rochester, Minn. This ... equally bad for the immune system, the authors noted. "These ...
... leads to a decrease in adult stem cells and ... the offspring, according to new research from the University ... annual Society for Neuroscience meeting in San Diego in ... for behavioral problems such as attention-deficit hyperactivity disorder (ADHD) ...
... FRIDAY, Dec. 3 (HealthDay News) -- The impending extinction ... remove an important buffer against the transmission of infectious ... by the U.S. National Science Foundation and National Institutes ... the U.S. Environmental Protection Agency, focused on how the ...
... quarter of Americans live in rural areas, which consistently ... areas. Among the complex causes for this disparity is that ... almost 4 out of 10 rural residents live at ... the time, transportation, and financial resources for travel to urban ...
Cached Medicine News:Health News:Assessing positive outcomes of phase III trials 2Health News:Nicotine exposure in pregnant rats puts offspring at risk for learning disabilities 2Health News:Species Extinctions May Spell Trouble for Human Health 2Health News:ALBERT EINSTEIN COLLEGE OF MEDICINE HELPS ADDRESS NEED FOR IMPROVED CANCER CARE IN RURAL AMERICA 2
(Date:8/4/2015)... JOLLA, Calif., Aug. 4, 2015   Regulus ... biopharmaceutical company leading the discovery and development of ... and highlights for the quarter ended June 30, ... highlights.  "The second quarter of ... of progression for Regulus," said Paul Grint, M.D., ...
(Date:8/4/2015)... , Aug. 4, 2015 Levi & Korsinsky ... ("Biogen" or the "Company") (NASDAQGS: BIIB) for possible violations ... and certain of its officers and/or directors have violated ... of 1934.  On Friday, July 24, 2015, prior to ... quarter 2015 financial results. Among other things, the Company ...
(Date:8/4/2015)... Aug. 4, 2015  Sutro Biopharma today announced ... Ph.D., as vice president of alliance and project ... in the management of Sutro,s collaborative partnerships and ... antibody-drug conjugates, bispecific antibodies and antibody-based therapeutics targeting ... than 22 years of experience in the biopharmaceutical ...
Breaking Medicine Technology:Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 2Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 3Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 4Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 5Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 6Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 7Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 8Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 9Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights 10SHAREHOLDER ALERT: Levi & Korsinsky, LLP Announces an Investigation of Biogen Inc. and Its Board of Directors in Connection with Possible Violations of Federal Securities Laws -- BIIB 2Sutro Biopharma Appoints Nicki Vasquez, Ph.D. as VP of Alliance and Project Management 2
... 2012 Ziehm Imaging, leading developer, ... award-winning product portfolio at this year,s Charing Cross ... ), its UK distribution partner, Ziehm Imaging showcases ... cardiologists to provide them with a flexible, cost-efficient ...
...  NxStage Medical, Inc. (Nasdaq: NXTM ), a ... to release its financial results for the first quarter ... before the opening of the financial markets. ... also host a conference call at 9:00 a.m. Eastern ...
Cached Medicine Technology:CX 2012: Elevating the Boundaries of Interventional Imaging with Mobile C-arms 2NxStage® to Report First Quarter Fiscal 2012 Financial Results 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: