Navigation Links
Childhood adversity may promote cellular aging
Date:3/16/2010

Philadelphia, PA, 16 March 2010 - Children who suffer physical or emotional abuse could be faced with accelerated cellular aging as adults, according to new research published by Elsevier in Biological Psychiatry.

It's an easy fact to forget - the aging process begins at birth. Despite this, cellular aging remains somewhat of a mystery, although there is growing evidence that over time, the DNA within cells begins to show signs of aging. One of these signs is the shortening of telomeres, which are DNA "caps" at the end of chromosomes that promote cellular stability.

Telomere length is a measure of biological aging because telomeres shorten progressively with each cell division. Shorter telomere lengths have been linked to a variety of aging-related medical conditions including cardiovascular disease and cancer.

Stress and trauma, such as childhood abuse and neglect, are risk factors for several medical and psychiatric illnesses, and stress is known to promote cellular aging. So, Audrey Tyrka and her colleagues from Butler Hospital and Brown University examined the DNA of healthy adults who had a history of childhood maltreatment and found they had shorter telomeres than those who did not experience child maltreatment.

Dr. Tyrka explained that the findings "suggest the possibility that early developmental experiences may have profound effects on biology that can influence cellular mechanisms at a very basic level and even lead to accelerated aging."

Dr. John Krystal, Editor of Biological Psychiatry, agreed: "This study illustrates a new way that early childhood adversity may leave its mark on traumatized individuals. Our limited insight into the functional significance of telomere shortening makes it difficult to know whether there are some adaptive consequences of these changes. Yet the association of telomere shortening and cellular aging suggests that there might be long-term health implications of exposure to early childhood adversity."


'/>"/>

Contact: Maureen Hunter
m.hunter@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Related medicine news :

1. Genetic predisposition increases childhood asthma risk
2. Treating diabetes during pregnancy can break link to childhood obesity
3. Childhood asthma still inappropriately treated in the UK
4. Screening Proposed for Childhood Cholesterol Levels
5. Success of Shape-Up Somerville Childhood Obesity Intervention to be Presented at the Friedman School Symposium at Tufts, October 29-31, 2007 - Boston
6. Success of Shape Up Somerville childhood obesity intervention to be presented
7. Childhood vaccination may protect adult eyes
8. Childhood Obesity Epidemic a Long-Term Challenge
9. New chemotherapy regimen prolongs survival in difficult-to-treat childhood brainstem gliomas
10. Antibiotics Not Always Best Bet for Battling Childhood Ear Infections
11. Childhood TV viewing a risk for behavior problems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... ... February 12, 2016 , ... The Journal of Pain ... 0.416 in 2013. The SJR uses data taken from the Scopus database (Elsevier B.V.) ... number of citations received by the journal over a three year period and also ...
(Date:2/11/2016)... ... ... Hall Integrative Health and Chiropractic, PC which focuses on ... in March. All seven practices are set to start accepting patients in March ... According to this 2011 CNN article it is possible: http://www.cnn.com/2011/HEALTH/01/28/reverse.diabetes/ . Current ...
(Date:2/11/2016)... DC (PRWEB) , ... February 11, 2016 , ... ... an upcoming Feb. 23 webinar, “Intel’s Direct-to-Employee Benefit Model: A Case Study for ... not-for-profit Catholic health care system that’s partnering with Intel on value-based health benefits ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... as General Counsel. Garrett will focus on contract negotiations, corporate strategy and healthcare ... security law, and best practices in data breaches for the Part D Star ...
(Date:2/11/2016)... , ... February 11, 2016 , ... ... updated its hallmark resource, Infusion Therapy Standards of Practice, to include vascular visualization ... illumination with an estimated 85% share of the market, facilitates adherence to this ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... -- Walgreens has committed to provide drug disposal kiosks ... D.C. as part of a program to combat ... advocacy organization As You Sow. Conrad MacKerron , ... on to unneeded drugs because they lack easily accessible collection ... --> Conrad MacKerron , Senior Vice President at As ...
(Date:2/11/2016)... 11, 2016   Health 2.0 , the premiere ... technologies, announced today " 10 Year Global Retrospective ", ... over the past ten years.   ... Health 2.0 has served as the preeminent thought-leader in ... thousands of technologies, companies, innovators, and patient-activists through an ...
(Date:2/11/2016)... , Feb. 11, 2016  NOIT™ Research LLC, a ... "Gift of Change" campaign to assist needy families in ... such unit sold between February 10, 2016 and March ... a needy family. The NOIT is an auditory stimulus ... individuals develop language skills. Beth Shier ...
Breaking Medicine Technology: